Detailed information NTG0687021

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: M3I20_RS02360
• Genome accession: NZ_CP097093
• Coordinates: 532117..532851 (+)
• Length: 244 a.a.
• NCBI ID: WP_106056499.1
• Uniprot ID: A0A2S0L2R0
• Organism: MAG: Mogibacterium diversum isolate JCVI-JB-Md32
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 527117..537851

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M3I20_RS02345 (M3I20_02345)	-	527382..528065 (+)	684	WP_106056493.1	helix-turn-helix transcriptional regulator	-
M3I20_RS02350 (M3I20_02350)	-	528371..530041 (+)	1671	WP_106056495.1	formate--tetrahydrofolate ligase	-
M3I20_RS02355 (M3I20_02355)	-	530170..531960 (+)	1791	WP_273135538.1	aminopeptidase P family N-terminal domain-containing protein	-
M3I20_RS02360 (M3I20_02360)	comE/blpR	532117..532851 (+)	735	WP_106056499.1	response regulator transcription factor	Regulator
M3I20_RS02365 (M3I20_02365)	-	532874..534175 (+)	1302	WP_273067160.1	sensor histidine kinase	-
M3I20_RS02370 (M3I20_02370)	-	534392..535063 (+)	672	WP_106056501.1	ABC transporter ATP-binding protein	-
M3I20_RS02375 (M3I20_02375)	-	535068..535781 (+)	714	WP_106056503.1	ABC transporter	-
M3I20_RS02380 (M3I20_02380)	-	536007..537566 (-)	1560	WP_106056505.1	hypothetical protein	-

Sequence

Protein

• Length: 244 a.a.
• Molecular weight: 28309.62 Da
• Isoelectric Point: 5.0906

>NTDB_id=687021 M3I20_RS02360 WP_106056499.1 532117..532851(+) (comE/blpR) [MAG: Mogibacterium diversum isolate JCVI-JB-Md32]
MINIFILEDEILQQSRIDNIIREVIDQKDLKCKTPEIFSSPKQMLDNISEFGSHQLFFLDIEIKGEEQKGLDIAKEIRSR
DPNATIVFVTTHTEFMPVTFKYKVAALDFIDKALDEELFKERVCSAIEYTICKVGSNIAQDSFAIETSMARVQVPFNNIL
YFETSPMIHKVILHTKDERMEFYGSIADVEKADSRLYRCHRSFVVNPDNIIKIDKESKIALFENGESCLISRMKYRGLLE
KLNY

Nucleotide

• Length: 735 bp

>NTDB_id=687021 M3I20_RS02360 WP_106056499.1 532117..532851(+) (comE/blpR) [MAG: Mogibacterium diversum isolate JCVI-JB-Md32]
ATGATTAATATATTCATTTTAGAAGATGAGATACTGCAGCAATCACGAATCGACAATATAATCAGGGAAGTGATTGACCA
GAAAGATTTGAAGTGCAAAACTCCAGAAATTTTTAGCAGTCCGAAGCAGATGCTAGATAATATCTCAGAATTCGGTTCCC
ATCAACTGTTTTTCCTTGATATCGAGATTAAGGGAGAAGAACAGAAGGGACTGGATATTGCTAAGGAAATTCGTAGCCGA
GATCCTAATGCGACAATCGTATTTGTAACAACGCATACAGAGTTTATGCCTGTTACGTTTAAATATAAAGTAGCTGCGCT
AGATTTTATCGATAAAGCACTTGATGAAGAGTTATTCAAAGAGCGAGTGTGCTCGGCTATCGAGTACACTATCTGCAAGG
TTGGATCAAACATAGCTCAAGATTCGTTCGCTATTGAAACATCCATGGCACGTGTACAGGTACCGTTTAATAATATATTG
TATTTCGAGACTTCTCCGATGATCCACAAAGTAATTTTGCATACTAAAGATGAACGTATGGAGTTTTATGGTAGCATCGC
TGATGTTGAGAAGGCTGATAGTCGCCTCTACCGCTGTCACCGATCATTTGTAGTTAATCCTGATAATATAATTAAGATAG
ATAAGGAGAGCAAGATTGCTCTGTTTGAAAATGGAGAGAGCTGTCTGATATCAAGGATGAAGTACAGAGGTCTTCTTGAA
AAACTCAATTATTAG

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (152-242)

• Response regulator receiver domain (Response_reg) (4-122)

3D structure

• AlphaFold DB: A0A2S0L2R0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	52.301	97.951	0.512
comE/comE1	Streptococcus equinus JB1	46.748	100	0.471
comE/comE2	Streptococcus gordonii strain NCTC7865	39.286	100	0.406
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	39.286	100	0.406
comE/comE2	Streptococcus equinus JB1	38.017	99.18	0.377
comE	Streptococcus mitis SK321	37.037	99.59	0.369
comE	Streptococcus mitis NCTC 12261	37.037	99.59	0.369