Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   KK0981_RS06470 Genome accession   NZ_AP017971
Coordinates   1218332..1219180 (-) Length   282 a.a.
NCBI ID   WP_000705309.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain KK0981     
Function   ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology)   
DNA processing Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1216833..1218181 1218332..1219180 flank 151


Gene organization within MGE regions


Location: 1216833..1219180
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KK0981_RS06465 - 1216833..1218181 (-) 1349 Protein_1230 IS3 family transposase -
  KK0981_RS06470 (KK0981_32670) dprA/cilB/dalA 1218332..1219180 (-) 849 WP_000705309.1 DNA-processing protein DprA Machinery gene

Sequence

Protein


Download         Length: 282 a.a.        Molecular weight: 31060.71 Da        Isoelectric Point: 5.2064

>NTDB_id=68685 KK0981_RS06470 WP_000705309.1 1218332..1219180(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain KK0981]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDYLALSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide


Download         Length: 849 bp        

>NTDB_id=68685 KK0981_RS06470 WP_000705309.1 1218332..1219180(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain KK0981]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATCTCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGTATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAACAAACGCTTGCAAGACTACATCGGCAATGA
CTATCTGGCTCTAAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACGTGTGAGCGAGCAATGGAAGAA
GGACGCGATGTCTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(75-271)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(3-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

99.291

100

0.993
  dprA/cilB/dalA Streptococcus pneumoniae D39

99.291

100

0.993
  dprA/cilB/dalA Streptococcus pneumoniae R6

99.291

100

0.993
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

99.291

100

0.993
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

97.872

100

0.979
  dprA/cilB/dalA Streptococcus mitis SK321

97.163

100

0.972
  dprA Streptococcus mutans UA159

62.857

99.291

0.624
  dprA Lactococcus lactis subsp. cremoris KW2

55.357

99.291

0.55
  dprA Staphylococcus aureus N315

37.456

100

0.376
  dprA Haemophilus influenzae Rd KW20

38.202

94.681

0.362

Multiple sequence alignment