Detailed information NTG0068678

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: KK0981_RS04680
• Genome accession: NZ_AP017971
• Coordinates: 870157..870807 (+)
• Length: 216 a.a.
• NCBI ID: WP_000387330.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain KK0981
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 865157..875807

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KK0981_RS04650 (KK0981_29150)	pyrH	865881..866618 (+)	738	WP_000002997.1	UMP kinase	-
KK0981_RS04655 (KK0981_29160)	frr	866627..867184 (+)	558	WP_000024409.1	ribosome recycling factor	-
KK0981_RS04660 (KK0981_29170)	cvfB	867244..868098 (+)	855	WP_001095450.1	RNA-binding virulence regulatory protein CvfB	-
KK0981_RS04665 (KK0981_29180)	-	868107..868322 (+)	216	WP_001232082.1	YozE family protein	-
KK0981_RS04670 (KK0981_29190)	-	868408..869412 (+)	1005	WP_000658177.1	PhoH family protein	-
KK0981_RS04675 (KK0981_29200)	-	869520..870089 (+)	570	WP_000443770.1	GNAT family N-acetyltransferase	-
KK0981_RS04680 (KK0981_29210)	comEA/celA/cilE	870157..870807 (+)	651	WP_000387330.1	ComEA family DNA-binding protein	Machinery gene
KK0981_RS04685 (KK0981_29220)	comEC/celB	870791..873031 (+)	2241	WP_000942411.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
KK0981_RS04690 (KK0981_29230)	-	873075..874028 (-)	954	WP_001155321.1	IS30-like element ISSpn8 family transposase	-
KK0981_RS04695 (KK0981_29240)	infC	874515..875045 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
KK0981_RS04700 (KK0981_29250)	rpmI	875078..875278 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
KK0981_RS04705 (KK0981_29260)	rplT	875330..875689 (+)	360	WP_000124836.1	50S ribosomal protein L20	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23229.65 Da
• Isoelectric Point: 5.5171

>NTDB_id=68678 KK0981_RS04680 WP_000387330.1 870157..870807(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain KK0981]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=68678 KK0981_RS04680 WP_000387330.1 870157..870807(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain KK0981]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTCGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGCCAACAGACTGGTTTGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (151-214)

• SLBB domain (SLBB) (76-126)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	100	100	1
comEA/celA/cilE	Streptococcus pneumoniae D39	100	100	1
comEA/celA/cilE	Streptococcus pneumoniae R6	100	100	1
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	97.222	100	0.972
comEA/celA/cilE	Streptococcus mitis NCTC 12261	96.296	100	0.963
comEA/celA/cilE	Streptococcus mitis SK321	90.278	100	0.903
comEA	Lactococcus lactis subsp. cremoris KW2	43.172	100	0.454
comEA	Bacillus subtilis subsp. subtilis str. 168	41.579	87.963	0.366
comEA	Latilactobacillus sakei subsp. sakei 23K	33.476	100	0.361