Detailed information NTG0068670

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: KK0981_RS02660
• Genome accession: NZ_AP017971
• Coordinates: 492813..494489 (-)
• Length: 558 a.a.
• NCBI ID: WP_319014187.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain KK0981
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 487813..499489

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KK0981_RS02630 (KK0981_25240)	-	488148..488477 (-)	330	WP_000132572.1	hypothetical protein	-
KK0981_RS02635 (KK0981_25250)	-	488753..489091 (+)	339	WP_000682118.1	LytTR family DNA-binding domain-containing protein	-
KK0981_RS02640 (KK0981_25260)	comE/blpR	489096..489833 (+)	738	WP_001219145.1	response regulator transcription factor	Regulator
KK0981_RS02645 (KK0981_25270)	-	489847..491187 (+)	1341	WP_001017624.1	sensor histidine kinase	-
KK0981_RS02650 (KK0981_25280)	blpC	491229..491384 (-)	156	WP_000358817.1	quorum-sensing system pheromone BlpC	-
KK0981_RS02655 (KK0981_25290)	-	491441..492802 (-)	1362	WP_001069090.1	bacteriocin secretion accessory protein	-
KK0981_RS02660 (KK0981_25300)	comA/nlmT	492813..494489 (-)	1677	WP_319014187.1	peptide cleavage/export ABC transporter	Regulator
KK0981_RS12655 (KK0981_25310)	comA/nlmT	494383..494970 (-)	588	WP_050201397.1	cysteine peptidase family C39 domain-containing protein	Regulator
KK0981_RS02665 (KK0981_25320)	blpI	495268..495465 (+)	198	WP_001093259.1	bacteriocin-like peptide BlpI	-
KK0981_RS02675 (KK0981_25340)	blpJ	495932..496201 (+)	270	WP_001093248.1	bacteriocin-like peptide BlpJ	-
KK0981_RS02680 (KK0981_25350)	blpU	496270..496500 (+)	231	WP_000379964.1	bacteriocin-like peptide BlpU	-
KK0981_RS02685	-	496503..496622 (+)	120	WP_000346298.1	PncF family bacteriocin immunity protein	-
KK0981_RS02690 (KK0981_25360)	-	496919..497083 (+)	165	WP_000727118.1	hypothetical protein	-
KK0981_RS02695 (KK0981_25370)	-	497080..497484 (+)	405	WP_000846943.1	hypothetical protein	-
KK0981_RS02700	-	497687..498491 (+)	805	Protein_503	IS5 family transposase	-
KK0981_RS12580 (KK0981_25400)	blpM	498641..498889 (+)	249	Protein_504	two-peptide bacteriocin subunit BlpM	-
KK0981_RS12795	blpN	498878..498988 (+)	111	Protein_505	two-peptide bacteriocin subunit BlpN	-
KK0981_RS02715 (KK0981_25410)	cipB	499232..499381 (+)	150	WP_001818346.1	bacteriocin-like peptide BlpO	Regulator

Sequence

Protein

• Length: 558 a.a.
• Molecular weight: 62921.27 Da
• Isoelectric Point: 7.3451

>NTDB_id=68670 KK0981_RS02660 WP_319014187.1 492813..494489(-) (comA/nlmT) [Streptococcus pneumoniae strain KK0981]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIENINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKS
PVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIKVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 1677 bp

>NTDB_id=68670 KK0981_RS02660 WP_319014187.1 492813..494489(-) (comA/nlmT) [Streptococcus pneumoniae strain KK0981]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAAATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGAT
TAGTCAAGAAGATATTCTAAAAGCTTGTGAAGTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCT
CCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTAAAGTTGGTAGCCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (10-279)

• ABC transporter (ABC_tran) (341-490)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.352	99.821	0.722
comA	Streptococcus mitis NCTC 12261	66.667	100	0.667
comA	Streptococcus pneumoniae D39	66.308	100	0.663
comA	Streptococcus pneumoniae R6	66.308	100	0.663
comA	Streptococcus pneumoniae Rx1	66.308	100	0.663
comA	Streptococcus gordonii str. Challis substr. CH1	66.011	100	0.661
comA	Streptococcus mitis SK321	66.129	100	0.661
comA	Streptococcus pneumoniae TIGR4	65.95	100	0.66