Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   SNAG_RS06265 Genome accession   NZ_AP017652
Coordinates   1202875..1203525 (-) Length   216 a.a.
NCBI ID   WP_096407600.1    Uniprot ID   A0A1E1GBE8
Organism   Streptococcus sp. NPS 308     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1197875..1208525
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SNAG_RS06240 (SNAG_1220) - 1198817..1199197 (-) 381 WP_096407595.1 VOC family protein -
  SNAG_RS06245 (SNAG_1221) rplT 1199256..1199615 (-) 360 WP_000124832.1 50S ribosomal protein L20 -
  SNAG_RS06250 (SNAG_1222) rpmI 1199667..1199867 (-) 201 WP_001125942.1 50S ribosomal protein L35 -
  SNAG_RS06255 (SNAG_1223) infC 1199900..1200430 (-) 531 WP_000848184.1 translation initiation factor IF-3 -
  SNAG_RS06260 (SNAG_1224) comEC/celB 1200651..1202891 (-) 2241 WP_096407597.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SNAG_RS06265 (SNAG_1225) comEA/celA/cilE 1202875..1203525 (-) 651 WP_096407600.1 helix-hairpin-helix domain-containing protein Machinery gene
  SNAG_RS06270 (SNAG_1226) - 1203592..1204161 (-) 570 WP_096407603.1 GNAT family N-acetyltransferase -
  SNAG_RS06275 (SNAG_1227) ald 1204341..1205453 (+) 1113 WP_096407605.1 alanine dehydrogenase -
  SNAG_RS06280 (SNAG_1228) - 1205504..1206490 (-) 987 WP_049550008.1 PhoH family protein -
  SNAG_RS06285 (SNAG_1229) - 1206571..1206786 (-) 216 WP_001232084.1 YozE family protein -
  SNAG_RS06290 (SNAG_1230) - 1206783..1207388 (-) 606 WP_096407608.1 GrpB family protein -
  SNAG_RS06295 (SNAG_1231) cvfB 1207400..1208254 (-) 855 WP_096407610.1 RNA-binding virulence regulatory protein CvfB -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23255.51 Da        Isoelectric Point: 5.9312

>NTDB_id=68356 SNAG_RS06265 WP_096407600.1 1202875..1203525(-) (comEA/celA/cilE) [Streptococcus sp. NPS 308]
MEVIIEKIKEYKIIVICAGLGLALGGFFLLKPSTQKSVTETNLQAEVAAVSKDSSSEKEVKKEEKEEPLEQELITVDVKG
AVKSPGIYDLPVGSRVHDAVQKAGGLTEEADSKSLNLAQKVSDEALVYVPTKGEEAASQQATSGTTPSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHRETNGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=68356 SNAG_RS06265 WP_096407600.1 1202875..1203525(-) (comEA/celA/cilE) [Streptococcus sp. NPS 308]
ATGGAAGTCATTATCGAGAAAATCAAAGAGTATAAAATCATTGTCATATGTGCTGGTTTGGGTTTGGCCTTGGGCGGATT
TTTCTTGCTAAAGCCATCTACGCAAAAATCCGTCACAGAAACAAATTTGCAGGCTGAAGTCGCGGCCGTTTCAAAGGATT
CATCGTCTGAAAAAGAAGTGAAGAAGGAGGAAAAGGAAGAGCCTCTTGAACAAGAGCTGATTACAGTAGATGTCAAAGGT
GCTGTCAAATCACCGGGGATCTATGACTTGCCAGTAGGAAGTCGGGTCCATGATGCTGTTCAGAAAGCTGGTGGATTGAC
AGAGGAAGCAGATAGTAAGTCGCTCAATCTAGCACAGAAAGTCAGTGACGAGGCTCTTGTCTATGTTCCAACTAAGGGAG
AAGAAGCAGCTAGTCAGCAGGCTACCTCTGGAACGACTCCTTCGACAAGTAAAGAAAAGAAGGTCAACCTCAATAAAGCT
AGTCTGGAAGAACTCAAGCAGGTCAAAGGCTTGGGAGGAAAACGAGCCCAGGATATTATCGACCATCGTGAGACGAATGG
CAAATTCAAGTCGGTGGATGAGTTAAAGAAAGTTTCTGGCATTGGCGCTAAGACCATAGAAAAGTTAAAAGACTATGTTA
CGGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-126)

Helix-hairpin-helix motif (HHH_3)

(151-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E1GBE8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

91.204

100

0.912
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

90.741

100

0.907
  comEA/celA/cilE Streptococcus pneumoniae D39

88.889

100

0.889
  comEA/celA/cilE Streptococcus pneumoniae R6

88.889

100

0.889
  comEA/celA/cilE Streptococcus pneumoniae Rx1

88.889

100

0.889
  comEA/celA/cilE Streptococcus mitis SK321

86.574

100

0.866
  comEA Lactococcus lactis subsp. cremoris KW2

40

100

0.417
  comEA Latilactobacillus sakei subsp. sakei 23K

33.476

100

0.361

Multiple sequence alignment