Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC   Type   Machinery gene
Locus tag   MUA12_RS07000 Genome accession   NZ_CP095104
Coordinates   1379508..1379837 (-) Length   109 a.a.
NCBI ID   WP_107548333.1    Uniprot ID   -
Organism   Staphylococcus simulans strain IVB6179     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1374508..1384837
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA12_RS06975 (MUA12_06935) gcvPA 1375019..1376368 (-) 1350 WP_057510473.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -
  MUA12_RS06980 (MUA12_06940) gcvT 1376390..1377484 (-) 1095 WP_262576874.1 glycine cleavage system aminomethyltransferase GcvT -
  MUA12_RS06985 (MUA12_06945) - 1377663..1378202 (-) 540 WP_002481034.1 shikimate kinase -
  MUA12_RS06990 (MUA12_06950) comGF 1378367..1378861 (-) 495 WP_002481036.1 competence type IV pilus minor pilin ComGF -
  MUA12_RS06995 (MUA12_06955) comGD 1379080..1379505 (-) 426 WP_002481037.1 competence type IV pilus minor pilin ComGD -
  MUA12_RS07000 (MUA12_06960) comGC 1379508..1379837 (-) 330 WP_107548333.1 competence type IV pilus major pilin ComGC Machinery gene
  MUA12_RS07005 (MUA12_06965) comGB 1379855..1380928 (-) 1074 WP_262576876.1 competence type IV pilus assembly protein ComGB -
  MUA12_RS07010 (MUA12_06970) comGA 1380900..1381874 (-) 975 WP_002481040.1 competence type IV pilus ATPase ComGA Machinery gene
  MUA12_RS07015 (MUA12_06975) - 1381931..1382554 (-) 624 WP_057510470.1 MBL fold metallo-hydrolase -
  MUA12_RS07020 (MUA12_06980) - 1382554..1382883 (-) 330 WP_002481042.1 MTH1187 family thiamine-binding protein -
  MUA12_RS07025 (MUA12_06985) - 1382883..1383869 (-) 987 WP_002481043.1 ROK family glucokinase -
  MUA12_RS07030 (MUA12_06990) - 1383869..1384069 (-) 201 WP_002481044.1 YqgQ family protein -

Sequence

Protein


Download         Length: 109 a.a.        Molecular weight: 12084.23 Da        Isoelectric Point: 9.6828

>NTDB_id=675461 MUA12_RS07000 WP_107548333.1 1379508..1379837(-) (comGC) [Staphylococcus simulans strain IVB6179]
MKNLVKNLKHKYIRAFTLLEMLLVLLVISVLLILIIPNIAKQSKHVQDTGCEAQQKMVNSQIEAFTLNKNRAPSSIDELV
SEGFLKEGQKTCKSGKTITISDGEATVSQ

Nucleotide


Download         Length: 330 bp        

>NTDB_id=675461 MUA12_RS07000 WP_107548333.1 1379508..1379837(-) (comGC) [Staphylococcus simulans strain IVB6179]
ATGAAAAACCTTGTCAAAAACTTAAAACATAAATATATACGAGCATTTACTTTACTAGAAATGCTTTTAGTTCTTTTAGT
TATCAGTGTTTTATTGATACTCATTATTCCAAATATTGCTAAACAATCTAAGCATGTTCAAGATACTGGGTGTGAAGCAC
AACAAAAAATGGTGAATAGCCAAATAGAAGCTTTTACTCTAAATAAAAATAGAGCGCCTTCTTCAATCGATGAATTAGTT
AGTGAAGGATTTTTAAAAGAAGGTCAAAAAACATGTAAATCTGGAAAAACGATTACAATCAGCGACGGCGAAGCTACCGT
TAGTCAATAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(13-35)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Staphylococcus aureus N315

72.632

87.156

0.633
  comGC Staphylococcus aureus MW2

72.632

87.156

0.633
  comGC/cglC Streptococcus pneumoniae TIGR4

41.905

96.33

0.404
  comGC Bacillus subtilis subsp. subtilis str. 168

42.708

88.073

0.376
  comGC/cglC Streptococcus mitis SK321

46.067

81.651

0.376
  comGC/cglC Streptococcus mitis NCTC 12261

46.067

81.651

0.376
  comGC/cglC Streptococcus pneumoniae D39

44.944

81.651

0.367
  comGC/cglC Streptococcus pneumoniae Rx1

44.944

81.651

0.367
  comGC/cglC Streptococcus pneumoniae R6

44.944

81.651

0.367