Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   MUB28_RS03840 Genome accession   NZ_CP094945
Coordinates   728694..728855 (-) Length   53 a.a.
NCBI ID   WP_014727422.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain VHProbi R08     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 707926..736609 728694..728855 within 0


Gene organization within MGE regions


Location: 707926..736609
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUB28_RS03755 (MUB28_03755) - 707926..708516 (+) 591 WP_011227082.1 thymidine kinase -
  MUB28_RS03760 (MUB28_03760) prfA 708559..709638 (+) 1080 WP_002948472.1 peptide chain release factor 1 -
  MUB28_RS03765 (MUB28_03765) prmC 709635..710468 (+) 834 WP_011681016.1 peptide chain release factor N(5)-glutamine methyltransferase -
  MUB28_RS03770 (MUB28_03770) - 710455..711060 (+) 606 WP_002948474.1 L-threonylcarbamoyladenylate synthase -
  MUB28_RS03775 (MUB28_03775) glyA 711155..712405 (+) 1251 WP_014727417.1 serine hydroxymethyltransferase -
  MUB28_RS03780 (MUB28_03780) - 712412..713389 (+) 978 WP_014608183.1 nucleoid-associated protein -
  MUB28_RS03785 (MUB28_03785) - 713391..714002 (+) 612 WP_041827329.1 lysozyme family protein -
  MUB28_RS03790 (MUB28_03790) - 714035..715774 (+) 1740 WP_011681019.1 ABC transporter ATP-binding protein -
  MUB28_RS03795 (MUB28_03795) - 715764..717512 (+) 1749 WP_011681020.1 ABC transporter ATP-binding protein -
  MUB28_RS03800 (MUB28_03800) - 717690..717821 (+) 132 WP_002885174.1 teichoic acid D-Ala incorporation-associated protein DltX -
  MUB28_RS03805 (MUB28_03805) dltA 717830..719380 (+) 1551 WP_011681022.1 D-alanine--poly(phosphoribitol) ligase subunit DltA -
  MUB28_RS03810 (MUB28_03810) dltB 719377..720624 (+) 1248 WP_014608186.1 D-alanyl-lipoteichoic acid biosynthesis protein DltB -
  MUB28_RS03815 (MUB28_03815) dltC 720642..720881 (+) 240 WP_002950439.1 D-alanine--poly(phosphoribitol) ligase subunit DltC -
  MUB28_RS03820 (MUB28_03820) dltD 720874..722142 (+) 1269 WP_011681024.1 D-alanyl-lipoteichoic acid biosynthesis protein DltD -
  MUB28_RS03825 (MUB28_03825) - 722195..723544 (-) 1350 Protein_705 IS3 family transposase -
  MUB28_RS03830 (MUB28_03830) - 723743..726379 (-) 2637 WP_014727421.1 calcium-translocating P-type ATPase, PMCA-type -
  MUB28_RS03835 (MUB28_03835) pabB 726556..728274 (-) 1719 WP_014608193.1 aminodeoxychorismate synthase component I -
  MUB28_RS03840 (MUB28_03840) prx 728694..728855 (-) 162 WP_014727422.1 hypothetical protein Regulator
  MUB28_RS03845 (MUB28_03845) - 729339..729614 (-) 276 WP_014727423.1 hypothetical protein -
  MUB28_RS03850 (MUB28_03850) - 729631..729813 (-) 183 WP_014727424.1 hypothetical protein -
  MUB28_RS03855 (MUB28_03855) - 730142..731215 (-) 1074 WP_014727425.1 VapE domain-containing protein -
  MUB28_RS03860 (MUB28_03860) - 731551..732408 (-) 858 WP_014727426.1 primase alpha helix C-terminal domain-containing protein -
  MUB28_RS03865 (MUB28_03865) - 732423..732695 (-) 273 WP_011227098.1 MerR family transcriptional regulator -
  MUB28_RS03870 (MUB28_03870) - 732697..733038 (-) 342 WP_224102964.1 hypothetical protein -
  MUB28_RS03875 (MUB28_03875) - 733025..733261 (-) 237 WP_014727428.1 hypothetical protein -
  MUB28_RS03880 (MUB28_03880) - 733275..733469 (-) 195 WP_014727429.1 hypothetical protein -
  MUB28_RS03885 (MUB28_03885) - 733473..733778 (-) 306 WP_014727430.1 hypothetical protein -
  MUB28_RS03890 (MUB28_03890) - 733998..734195 (-) 198 WP_014727431.1 helix-turn-helix transcriptional regulator -
  MUB28_RS03895 (MUB28_03895) - 734358..734876 (+) 519 WP_002948197.1 helix-turn-helix transcriptional regulator -
  MUB28_RS03900 (MUB28_03900) - 734992..736158 (+) 1167 WP_014727432.1 site-specific integrase -
  MUB28_RS03905 (MUB28_03905) - 736274..736609 (+) 336 WP_011225805.1 hypothetical protein -

Sequence

Protein


Download         Length: 53 a.a.        Molecular weight: 6084.95 Da        Isoelectric Point: 4.2412

>NTDB_id=674404 MUB28_RS03840 WP_014727422.1 728694..728855(-) (prx) [Streptococcus thermophilus strain VHProbi R08]
MLTYDEFKEAMDKGFIKGDTVQIVRLDGEQVEPREILSLEKVSDIIKELGKDN

Nucleotide


Download         Length: 162 bp        

>NTDB_id=674404 MUB28_RS03840 WP_014727422.1 728694..728855(-) (prx) [Streptococcus thermophilus strain VHProbi R08]
ATGCTGACTTATGATGAATTTAAAGAGGCAATGGACAAGGGTTTTATTAAAGGTGATACTGTCCAGATTGTCCGATTAGA
CGGTGAACAAGTTGAGCCACGCGAAATATTGAGCTTAGAAAAGGTATCGGATATAATAAAGGAACTAGGCAAGGACAACT
AA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS8232

48.333

100

0.547
  prx Streptococcus pyogenes MGAS315

46.667

100

0.528
  prx Streptococcus pyogenes MGAS315

46.667

100

0.528
  prx Streptococcus pyogenes MGAS315

45

100

0.509
  prx Streptococcus pyogenes MGAS315

56.818

83.019

0.472
  prx Streptococcus pyogenes MGAS315

57.143

79.245

0.453
  prx Streptococcus pyogenes MGAS315

60.526

71.698

0.434