Detailed information NTG0673473

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: OG784_RS27295
• Genome accession: NZ_CP109298
• Coordinates: 5996930..5997592 (+)
• Length: 220 a.a.
• NCBI ID: WP_329451009.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_01617
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 5991930..6002592

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG784_RS27275 (OG784_27280)	mce	5993347..5993775 (-)	429	WP_030916038.1	methylmalonyl-CoA epimerase	-
OG784_RS27280 (OG784_27285)	-	5993911..5995113 (+)	1203	WP_030971497.1	acetyl-CoA C-acetyltransferase	-
OG784_RS27285 (OG784_27290)	meaB	5995158..5996114 (+)	957	WP_313939238.1	methylmalonyl Co-A mutase-associated GTPase MeaB	-
OG784_RS27290 (OG784_27295)	-	5996351..5996809 (-)	459	WP_406326656.1	PepSY domain-containing protein	-
OG784_RS27295 (OG784_27300)	ciaR	5996930..5997592 (+)	663	WP_329451009.1	response regulator transcription factor	Regulator
OG784_RS27300 (OG784_27305)	-	5997589..5999097 (+)	1509	WP_406326659.1	ATP-binding protein	-
OG784_RS27305 (OG784_27310)	-	5999194..5999670 (-)	477	WP_313939242.1	MarR family transcriptional regulator	-
OG784_RS27310 (OG784_27315)	-	5999807..6000589 (-)	783	WP_313939243.1	AIM24 family protein	-
OG784_RS27315 (OG784_27320)	-	6000586..6001236 (-)	651	WP_030916049.1	AIM24 family protein	-
OG784_RS27320 (OG784_27325)	-	6001236..6001868 (-)	633	WP_037689357.1	AIM24 family protein	-
OG784_RS27325 (OG784_27330)	-	6002080..6002430 (+)	351	WP_030971481.1	DUF3817 domain-containing protein	-
OG784_RS27330 (OG784_27335)	-	6002427..6002561 (+)	135	Protein_5388	MTH1187 family thiamine-binding protein	-

Sequence

Protein

• Length: 220 a.a.
• Molecular weight: 23589.19 Da
• Isoelectric Point: 5.1360

>NTDB_id=673473 OG784_RS27295 WP_329451009.1 5996930..5997592(+) (ciaR) [Streptomyces sp. NBC_01617]
MRLLIVEDEKRLAMSLAGGLTAEGFAVDVVHDGLEGLHRAGGGAYDLVVLDIMLPGLNGYRVCAALRAAGHEVPILMLTA
KDGEYDEAEGLDTGADDYLTKPFSYVVLVARIRALLRRRGGGSASPVLTVGALRMDTAARRVLLGEDEVALTAKEFAVLE
QLALRAGQVVSKADILEHVWDFAYDGDPNIVEVYVSALRRKLSAAAIRTVRGAGYRLEAL

Nucleotide

• Length: 663 bp

>NTDB_id=673473 OG784_RS27295 WP_329451009.1 5996930..5997592(+) (ciaR) [Streptomyces sp. NBC_01617]
ATGCGTCTGTTGATAGTGGAGGACGAGAAGCGGCTGGCGATGTCCCTGGCCGGGGGGCTCACCGCCGAGGGCTTCGCCGT
GGACGTCGTGCACGACGGGCTCGAAGGGCTGCACCGGGCGGGCGGAGGGGCGTACGACCTCGTCGTTCTCGACATCATGC
TGCCGGGGTTGAACGGCTACCGGGTCTGCGCCGCCCTGCGCGCCGCCGGCCACGAGGTGCCGATCCTGATGCTGACGGCC
AAGGACGGGGAGTACGACGAGGCGGAGGGGCTGGACACCGGCGCCGACGACTATCTGACCAAGCCGTTCTCGTACGTGGT
GCTGGTCGCCCGGATCCGGGCACTGCTGCGGCGCCGGGGCGGCGGTTCCGCCTCGCCCGTGCTCACCGTCGGCGCGCTGA
GGATGGATACCGCTGCTCGCCGCGTCCTCCTCGGTGAGGACGAAGTCGCCCTCACCGCCAAGGAGTTCGCCGTGCTGGAG
CAGCTGGCCCTGCGGGCGGGACAGGTGGTCAGCAAGGCGGACATCCTGGAACACGTCTGGGACTTCGCGTACGACGGGGA
CCCGAACATCGTCGAGGTGTACGTGAGCGCGCTGCGGCGCAAGCTCTCCGCCGCGGCCATCCGTACGGTGCGCGGCGCCG
GCTACCGGCTGGAGGCGCTGTGA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (147-217)

• Response regulator receiver domain (Response_reg) (4-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	41.256	100	0.418
vicR	Streptococcus mutans UA159	38.793	100	0.409
micA	Streptococcus pneumoniae Cp1015	37.021	100	0.395
ciaR	Streptococcus pneumoniae Rx1	39.013	100	0.395
ciaR	Streptococcus pneumoniae D39	39.013	100	0.395
ciaR	Streptococcus pneumoniae R6	39.013	100	0.395
ciaR	Streptococcus pneumoniae TIGR4	39.013	100	0.395
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.914	100	0.391
covR	Streptococcus salivarius strain HSISS4	38.288	100	0.386