Detailed information NTG0067294

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: SITYG_RS10245
• Genome accession: NZ_AP014880
• Coordinates: 2004842..2006032 (+)
• Length: 396 a.a.
• NCBI ID: WP_020999302.1
• Uniprot ID: -
• Organism: Streptococcus intermedius strain TYG1620
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1999842..2011032

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SITYG_RS10220 (SITYG_20150)	comE	2001645..2002394 (-)	750	WP_096363305.1	competence system response regulator transcription factor ComE	Regulator
SITYG_RS10225 (SITYG_20160)	comD/comD1	2002394..2003719 (-)	1326	WP_221761483.1	GHKL domain-containing protein	Regulator
SITYG_RS10230 (SITYG_20170)	-	2003736..2003882 (-)	147	WP_003075491.1	bacteriocin	-
SITYG_RS10240 (SITYG_20180)	rlmH	2004159..2004638 (-)	480	WP_096363307.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
SITYG_RS10245 (SITYG_20190)	htrA	2004842..2006032 (+)	1191	WP_020999302.1	S1C family serine protease	Regulator
SITYG_RS10250 (SITYG_20200)	spo0J	2006087..2006854 (+)	768	WP_096363308.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 396 a.a.
• Molecular weight: 41833.94 Da
• Isoelectric Point: 10.1393

>NTDB_id=67294 SITYG_RS10245 WP_020999302.1 2004842..2006032(+) (htrA) [Streptococcus intermedius strain TYG1620]
MKNSSNFTKKFLWLFMVLAIGFIGGLLGNVTSSKLNKNNTTTTKVNHVTTSYKNTNSTTQAVNKVKDAVVSVITYANNKS
QNSIFGNDDFNSNNNNSQRVASEGSGVIYKKDSKYAYLVTNTHVINGASKVDIRLADGNKVPGEIVGSDTYSDISVVRIS
ASKVKSVAEFGDSSKLTVGETAIAIGSPLGSNYANTVTQGIISSLNRNVSLKSEDGQTISTQAIQTDTAINPGNSGGPLV
NIQGQVIGITSSKIASNRGTSVEGLGFAIPSNDVTNIISQLESNGAVTRPALGIQMIDISNLSSSDLSRLKLPAKVTAGV
VVRSAQSGMPAAGKLQKYDVITKIDGKDISSANDLQSALYKHSIGDDIKITFYRNGKETTTTIKLTKSTKDLNSNN

Nucleotide

• Length: 1191 bp

>NTDB_id=67294 SITYG_RS10245 WP_020999302.1 2004842..2006032(+) (htrA) [Streptococcus intermedius strain TYG1620]
ATGAAAAACTCTTCAAATTTCACAAAAAAATTCTTATGGCTTTTCATGGTCTTAGCTATAGGTTTTATTGGTGGTTTATT
AGGAAATGTAACTTCTTCAAAATTAAATAAAAACAACACAACTACTACTAAGGTTAACCATGTTACTACATCTTATAAAA
ATACCAATTCTACAACACAGGCGGTCAATAAAGTAAAGGATGCTGTTGTTTCTGTTATTACCTATGCTAATAATAAATCT
CAAAATAGCATTTTTGGAAATGATGACTTTAATAGTAACAATAATAACTCACAAAGAGTAGCAAGCGAAGGTTCAGGGGT
TATTTATAAAAAAGACAGTAAGTATGCCTATCTTGTAACTAATACTCATGTTATTAATGGTGCTAGTAAAGTGGATATTC
GTTTAGCGGATGGTAACAAAGTTCCAGGAGAAATCGTAGGCTCAGATACTTACTCAGATATTTCTGTCGTCCGTATTAGT
GCAAGCAAAGTCAAGTCAGTTGCTGAATTTGGTGATTCTAGTAAATTAACTGTTGGAGAAACTGCTATTGCTATTGGTAG
CCCACTTGGATCAAATTATGCAAATACTGTTACTCAAGGAATTATTTCTAGCTTAAATCGTAATGTGTCTTTAAAATCTG
AAGATGGTCAAACTATCTCTACTCAGGCTATTCAAACAGATACAGCGATTAATCCTGGGAATTCTGGTGGTCCACTTGTA
AATATCCAAGGGCAAGTTATTGGTATTACTTCAAGTAAAATTGCTAGTAATCGTGGAACATCTGTAGAGGGATTAGGTTT
TGCTATTCCATCTAATGATGTCACCAACATCATCAGCCAATTGGAATCAAACGGAGCAGTTACGCGACCAGCTTTAGGAA
TTCAAATGATTGATATTAGTAATCTATCTAGTTCTGATTTATCACGTTTGAAACTTCCAGCAAAAGTGACTGCAGGAGTT
GTTGTTCGTTCAGCTCAGTCTGGAATGCCTGCAGCAGGAAAACTTCAAAAATATGATGTTATTACAAAGATAGATGGAAA
AGACATTTCCTCAGCAAATGATTTACAATCTGCTTTATACAAACATTCAATTGGTGATGATATAAAAATTACATTTTATC
GTAATGGAAAAGAAACAACCACCACCATTAAACTTACAAAATCTACAAAAGATTTAAATTCAAATAATTGA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (290-385)

• Trypsin-like peptidase domain (Trypsin_2) (104-249)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	74.442	100	0.758
htrA	Streptococcus mitis NCTC 12261	71.537	100	0.717
htrA	Streptococcus pneumoniae D39	71.285	100	0.715
htrA	Streptococcus pneumoniae TIGR4	71.285	100	0.715
htrA	Streptococcus pneumoniae R6	71.285	100	0.715
htrA	Streptococcus pneumoniae Rx1	71.285	100	0.715
htrA	Streptococcus mutans UA159	57.033	98.737	0.563