Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   SITYG_RS10225 Genome accession   NZ_AP014880
Coordinates   2002394..2003719 (-) Length   441 a.a.
NCBI ID   WP_221761483.1    Uniprot ID   -
Organism   Streptococcus intermedius strain TYG1620     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1997394..2008719
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SITYG_RS10205 (SITYG_20140) - 1998745..2001321 (+) 2577 WP_096363304.1 YfhO family protein -
  SITYG_RS10220 (SITYG_20150) comE 2001645..2002394 (-) 750 WP_096363305.1 competence system response regulator transcription factor ComE Regulator
  SITYG_RS10225 (SITYG_20160) comD/comD1 2002394..2003719 (-) 1326 WP_221761483.1 GHKL domain-containing protein Regulator
  SITYG_RS10230 (SITYG_20170) - 2003736..2003882 (-) 147 WP_003075491.1 bacteriocin -
  SITYG_RS10240 (SITYG_20180) rlmH 2004159..2004638 (-) 480 WP_096363307.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SITYG_RS10245 (SITYG_20190) htrA 2004842..2006032 (+) 1191 WP_020999302.1 S1C family serine protease Regulator
  SITYG_RS10250 (SITYG_20200) spo0J 2006087..2006854 (+) 768 WP_096363308.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 51882.73 Da        Isoelectric Point: 8.7063

>NTDB_id=67293 SITYG_RS10225 WP_221761483.1 2002394..2003719(-) (comD/comD1) [Streptococcus intermedius strain TYG1620]
MVKIEFIYWVIFSIIEAISVVYCYKKISRVNKVNIHFTLLCLGIVFLTDFTTIIHYSVRYIMFFIQPLFFYLYFVKVKKV
KKHSSLFLALFLSLAVSGSETFFSVIISSVTGDKFVDRYWGLFYIFINIISLVFILKAIDYFKFNFKYFKKIDFKENIVQ
LNFYLLFIHLLLNVSHWLSNMKNLNSFSSMIATICFLMFMSILFYLQSIREKYEKEEQIKQKEQEQLQLQKYTDEIVNLY
NEIRGFRHDYGGMLASFQSAIHTGDIKEVERIYQEVLVNANLQLRSDKYTYFDLNNVGDSALRSVMTQTLFKARDYNIEL
TFEVKDFVKPLPIKLLDLVRMTSVLLNNAIEGAAESYQKTMNVSLVDLDTETILVIQNSRKKRPLDLEEIYQTDFSTKGV
GRGLGLSNIKEIINNYEGIILDTKIEDEYFIQAMRVRKEGL

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=67293 SITYG_RS10225 WP_221761483.1 2002394..2003719(-) (comD/comD1) [Streptococcus intermedius strain TYG1620]
ATGGTGAAAATAGAATTTATATATTGGGTTATATTCTCCATTATAGAAGCTATTTCTGTTGTATATTGTTATAAGAAGAT
AAGTAGAGTGAATAAAGTGAATATTCACTTTACTTTATTATGTTTAGGAATTGTATTTTTGACTGATTTTACTACAATAA
TACATTATTCGGTTAGATATATAATGTTTTTTATTCAACCATTATTTTTTTATTTATACTTTGTTAAAGTAAAAAAAGTT
AAAAAACATTCGTCTTTATTTTTAGCACTATTTTTATCTTTAGCTGTATCAGGTTCTGAAACCTTCTTTTCAGTTATTAT
TTCTTCTGTTACAGGTGATAAGTTTGTTGATAGATATTGGGGATTGTTCTATATTTTTATTAATATTATTTCTTTAGTTT
TCATTTTAAAAGCAATTGATTATTTTAAGTTTAATTTTAAATATTTTAAAAAGATAGATTTTAAAGAAAATATTGTACAA
TTAAATTTTTATCTATTATTTATTCATCTTTTATTAAATGTATCGCATTGGCTTAGTAACATGAAAAATTTAAATAGTTT
TTCTAGTATGATTGCTACAATTTGCTTTTTAATGTTTATGTCAATTTTATTCTACTTACAATCTATTCGCGAAAAATATG
AAAAAGAAGAACAAATTAAGCAAAAAGAACAGGAACAACTGCAATTACAAAAATATACAGATGAAATTGTTAATCTGTAT
AATGAAATTCGAGGTTTTCGTCATGATTATGGTGGGATGTTGGCAAGTTTTCAATCAGCTATTCATACAGGTGATATAAA
AGAAGTGGAGCGAATCTATCAGGAGGTTCTCGTAAATGCTAATTTACAGCTTCGTTCTGATAAATATACGTATTTTGATT
TAAATAATGTTGGAGATTCAGCACTTAGAAGTGTTATGACGCAAACATTGTTTAAGGCACGAGATTACAATATAGAATTA
ACATTTGAAGTAAAAGATTTTGTTAAACCTTTGCCAATTAAATTGTTAGATTTGGTTAGAATGACAAGTGTCCTTTTAAA
TAATGCAATAGAGGGAGCGGCAGAGAGTTATCAAAAAACGATGAATGTTTCTTTAGTAGATCTGGATACAGAAACGATCT
TAGTTATTCAAAATTCACGTAAGAAAAGACCTCTAGATTTGGAAGAAATATACCAAACTGATTTTTCAACAAAGGGTGTG
GGACGCGGTTTAGGTTTAAGTAATATTAAAGAAATTATTAATAACTATGAAGGAATTATTCTGGATACTAAAATCGAAGA
TGAATATTTTATACAAGCAATGAGAGTAAGGAAAGAAGGTTTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(334-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

54.566

99.32

0.542
  comD/comD2 Streptococcus gordonii strain NCTC7865

54.072

100

0.542
  comD Streptococcus mitis SK321

47.194

88.889

0.42
  comD/comD2 Streptococcus pneumoniae TIGR4

48.138

85.261

0.41
  comD Streptococcus mitis NCTC 12261

48.138

85.261

0.41
  comD/comD1 Streptococcus pneumoniae Rx1

47.606

85.261

0.406
  comD/comD1 Streptococcus pneumoniae D39

47.606

85.261

0.406
  comD/comD1 Streptococcus pneumoniae R6

47.606

85.261

0.406

Multiple sequence alignment