Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   SITYG_RS04260 Genome accession   NZ_AP014880
Coordinates   850771..851472 (+) Length   233 a.a.
NCBI ID   WP_003025150.1    Uniprot ID   A0A2I1UXK8
Organism   Streptococcus intermedius strain TYG1620     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 845771..856472
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SITYG_RS04240 (SITYG_08270) ccpA 846694..847698 (+) 1005 WP_020998737.1 catabolite control protein A Regulator
  SITYG_RS04245 (SITYG_08280) - 847791..848789 (+) 999 WP_096362761.1 glycosyltransferase family 4 protein -
  SITYG_RS04250 (SITYG_08290) - 848791..850104 (+) 1314 WP_096362762.1 glycosyltransferase family 4 protein -
  SITYG_RS04255 (SITYG_08300) - 850131..850472 (+) 342 WP_096362763.1 hypothetical protein -
  SITYG_RS04260 (SITYG_08310) micA 850771..851472 (+) 702 WP_003025150.1 response regulator YycF Regulator
  SITYG_RS04265 (SITYG_08320) micB 851465..852817 (+) 1353 WP_096362764.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SITYG_RS04270 (SITYG_08330) vicX 852819..853622 (+) 804 WP_003075634.1 MBL fold metallo-hydrolase Regulator
  SITYG_RS04275 (SITYG_08340) - 853631..853990 (+) 360 WP_096362765.1 YbaN family protein -
  SITYG_RS04280 (SITYG_08350) rnc 854379..855077 (+) 699 WP_003072976.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26887.86 Da        Isoelectric Point: 4.6824

>NTDB_id=67254 SITYG_RS04260 WP_003025150.1 850771..851472(+) (micA) [Streptococcus intermedius strain TYG1620]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAERPDILILDLMLPEMDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAAPTEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=67254 SITYG_RS04260 WP_003025150.1 850771..851472(+) (micA) [Streptococcus intermedius strain TYG1620]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAACCAATCTCAGATATTATAAAGTTTAACATGGTAAAAGAAGGTTATGA
AGTAGTGACTGCCTTCGACGGTCGCGAAGCGTTAGAAATGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGACTTAA
TGTTGCCCGAAATGGACGGCTTAGAGGTGGCGAGAACGATTCGGAAAACGAGTAATGTGCCAATCATCGTTCTTTCTGCC
AAAGACAGTGAGTTTGACAAAGTTATTGGTCTTGAGATTGGTGCAGATGACTATATGACAAAGCCTTTCTCTAATCGTGA
GTTGCAGGCGCGTGTCAAAGCTATTTTGCGTCGCACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGCTCCGACAG
AAATTGTGATTGGAGATTTGCAGATTTTGACCGATGCTTTTGTCGTGAAAAAGCATGGCGAAGAATTAGATTTAACACAC
CGTGAGTTTGAATTGCTCCACCATTTGGCAACGCATATCGGGCAAGTGATGACGCGTGAACATCTACTAGAAACGGTGTG
GGGTTATGATTATTTTGGAGATGTGCGGACTGTTGATGTGACAATTCGTCGTTTGAGAGAAAAGATAGAGGATATTCCTA
GCCGACCAGAGTACATTTTAACGCGGCGCGGCGTTGGATATTACATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2I1UXK8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.833

100

0.828
  vicR Streptococcus mutans UA159

79.237

100

0.803
  covR Streptococcus salivarius strain HSISS4

45.217

98.712

0.446
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.541

98.283

0.438
  scnR Streptococcus mutans UA159

36.052

100

0.361

Multiple sequence alignment