Detailed information NTG0067253

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SITYG_RS04240
• Genome accession: NZ_AP014880
• Coordinates: 846694..847698 (+)
• Length: 334 a.a.
• NCBI ID: WP_020998737.1
• Uniprot ID: D6RVW8
• Organism: Streptococcus intermedius strain TYG1620
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 841694..852698

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SITYG_RS04220 (SITYG_08230)	rfbB	842081..843127 (+)	1047	WP_096362757.1	dTDP-glucose 4,6-dehydratase	-
SITYG_RS04225 (SITYG_08240)	galE	843162..844181 (+)	1020	WP_096362758.1	UDP-glucose 4-epimerase GalE	-
SITYG_RS04230 (SITYG_08250)	-	844500..845081 (+)	582	WP_096362759.1	class I SAM-dependent methyltransferase	-
SITYG_RS04235 (SITYG_08260)	-	845348..846430 (-)	1083	WP_096362760.1	M24 family metallopeptidase	-
SITYG_RS04240 (SITYG_08270)	ccpA	846694..847698 (+)	1005	WP_020998737.1	catabolite control protein A	Regulator
SITYG_RS04245 (SITYG_08280)	-	847791..848789 (+)	999	WP_096362761.1	glycosyltransferase family 4 protein	-
SITYG_RS04250 (SITYG_08290)	-	848791..850104 (+)	1314	WP_096362762.1	glycosyltransferase family 4 protein	-
SITYG_RS04255 (SITYG_08300)	-	850131..850472 (+)	342	WP_096362763.1	hypothetical protein	-
SITYG_RS04260 (SITYG_08310)	micA	850771..851472 (+)	702	WP_003025150.1	response regulator YycF	Regulator

Sequence

Protein

• Length: 334 a.a.
• Molecular weight: 36810.90 Da
• Isoelectric Point: 5.5316

>NTDB_id=67253 SITYG_RS04240 WP_020998737.1 846694..847698(+) (ccpA) [Streptococcus intermedius strain TYG1620]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITSSYFA
TLAKGIDDIAEMYKYNIVLANSDEDDDKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATMDAVECLAKGNRKIAFVSGPLVDDINGKIRLAGYKEALKKAKCSYSEGLVFESKYSYDDGYQLAERVIASK
ATAAFVTGDELAAGLLNGLSDKGVNVPEDFEIITSDDSQVARFTRPNLTTIGQPLYDLGAISMRMLTKIMHKEELEEREV
VLAHGLIERCSTRK

Nucleotide

• Length: 1005 bp

>NTDB_id=67253 SITYG_RS04240 WP_020998737.1 846694..847698(+) (ccpA) [Streptococcus intermedius strain TYG1620]
ATGAACACAGACGATACTGTAACAATTTATGATGTCGCCCGTGAAGCGGGAGTTTCAATGGCGACCGTTAGCCGTGTAGT
AAACGGTAATAAAAATGTAAAGGAAAACACAAGAAAAAAAGTCTTAGAAGTCATTGACCGCCTTGACTATCGACCAAATG
CGGTAGCACGTGGACTTGCCAGCAAGAAAACGACTACAGTAGGAGTTGTCATTCCAAACATCACTAGCAGTTATTTTGCA
ACACTTGCGAAAGGAATTGATGATATTGCAGAGATGTATAAGTATAATATTGTCCTAGCTAATAGTGATGAAGATGATGA
CAAGGAAGTCTCTGTTGTTAATACGCTGTTTTCAAAGCAAGTAGATGGTATTATCTTTATGGGTTATCATCTGACAGAAA
AAATTCGTTCTGAGTTTTCTCGTTCAAGGACGCCAGTTGTACTTGCAGGAACAGTTGACGTTGAACATCAATTGCCAAGT
GTTAATATTGATTACAAACAAGCAACTATGGATGCGGTAGAATGTCTTGCAAAAGGCAACCGAAAAATTGCTTTTGTAAG
TGGACCTTTGGTAGATGATATTAATGGTAAGATTCGCTTGGCTGGCTACAAAGAAGCTTTGAAAAAAGCAAAATGTTCTT
ATAGCGAAGGGTTAGTCTTTGAGTCTAAATATAGTTATGATGATGGTTATCAATTAGCAGAACGCGTTATTGCTTCTAAA
GCAACGGCAGCTTTTGTGACTGGTGATGAGCTGGCAGCTGGACTGTTGAATGGCTTATCAGATAAAGGTGTGAATGTACC
AGAAGATTTTGAAATCATTACCAGTGATGATTCTCAGGTAGCACGTTTTACTCGCCCAAATTTGACAACTATTGGTCAGC
CCTTGTATGACCTTGGTGCAATTAGTATGCGTATGTTGACAAAGATTATGCACAAAGAAGAATTAGAAGAACGCGAAGTG
GTATTGGCACATGGTCTGATTGAGCGTTGTTCAACAAGGAAATAA

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-332)

3D structure

• AlphaFold DB: D6RVW8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	90.419	100	0.904
ccpA	Streptococcus pneumoniae D39	88.623	100	0.886
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	58.006	99.102	0.575