Detailed information NTG0671507

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: OHA26_RS28390
• Genome accession: NZ_CP109136
• Coordinates: 6211262..6211924 (+)
• Length: 220 a.a.
• NCBI ID: WP_326627196.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_01751
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 6206262..6216924

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHA26_RS28365 (OHA26_28380)	mce	6207685..6208113 (-)	429	WP_030916038.1	methylmalonyl-CoA epimerase	-
OHA26_RS28370 (OHA26_28385)	-	6208249..6209451 (+)	1203	WP_326627202.1	acetyl-CoA C-acetyltransferase	-
OHA26_RS28375 (OHA26_28390)	meaB	6209496..6210452 (+)	957	WP_326605810.1	methylmalonyl Co-A mutase-associated GTPase MeaB	-
OHA26_RS28380 (OHA26_28395)	-	6210562..6210711 (+)	150	WP_326815023.1	hypothetical protein	-
OHA26_RS28385 (OHA26_28400)	-	6210712..6211140 (-)	429	WP_326605812.1	PepSY domain-containing protein	-
OHA26_RS28390 (OHA26_28405)	ciaR	6211262..6211924 (+)	663	WP_326627196.1	response regulator transcription factor	Regulator
OHA26_RS28395 (OHA26_28410)	-	6211921..6213411 (+)	1491	WP_326815024.1	HAMP domain-containing sensor histidine kinase	-
OHA26_RS28400 (OHA26_28415)	-	6213572..6214048 (-)	477	WP_326605815.1	MarR family transcriptional regulator	-
OHA26_RS28405 (OHA26_28420)	-	6214186..6214968 (-)	783	WP_326817771.1	AIM24 family protein	-
OHA26_RS28410 (OHA26_28425)	-	6214965..6215615 (-)	651	WP_326817772.1	AIM24 family protein	-
OHA26_RS28415 (OHA26_28430)	-	6215615..6216247 (-)	633	WP_037689357.1	AIM24 family protein	-
OHA26_RS28420 (OHA26_28435)	-	6216459..6216809 (+)	351	WP_326627189.1	DUF3817 domain-containing protein	-

Sequence

Protein

• Length: 220 a.a.
• Molecular weight: 23876.42 Da
• Isoelectric Point: 5.6818

>NTDB_id=671507 OHA26_RS28390 WP_326627196.1 6211262..6211924(+) (ciaR) [Streptomyces sp. NBC_01751]
MRLLIVEDEKRLATSLARGLTAEGFAVDVVHDGLEGLHRAAEGAYDLVVLDIMLPGMNGYRVCAALRAAGHEVPILMLTA
KDGEYDEAEGLDTGADDYLTKPFSYVVLVARIRALLRRRGGGSASPVLTVGSLRMDTAARRVHLGEDEVTLTAKEFAVLE
QLALRAGRVVSKADILEHVWDFAYDGDPNIVEVYVSALRRKLSASAIRTVRGAGYRLEAL

Nucleotide

• Length: 663 bp

>NTDB_id=671507 OHA26_RS28390 WP_326627196.1 6211262..6211924(+) (ciaR) [Streptomyces sp. NBC_01751]
ATGCGTCTGTTGATCGTGGAGGACGAGAAGCGGCTGGCGACGTCTCTGGCCAGGGGACTCACCGCCGAGGGCTTCGCCGT
GGACGTCGTGCACGACGGCCTCGAAGGGCTGCACCGGGCGGCCGAAGGGGCGTACGACCTCGTCGTCCTCGACATCATGC
TGCCGGGGATGAACGGCTACCGGGTCTGCGCCGCTCTGCGCGCCGCCGGCCACGAGGTGCCGATCCTGATGCTGACGGCG
AAGGACGGGGAGTACGACGAGGCGGAGGGGCTGGACACCGGCGCCGACGACTATCTGACCAAGCCGTTCTCGTACGTGGT
GCTGGTCGCCCGGATCCGGGCACTCTTGCGGCGCCGGGGCGGCGGTTCGGCCTCACCCGTGCTCACCGTCGGCTCACTGC
GGATGGACACCGCCGCCCGCCGCGTCCACCTCGGAGAGGACGAAGTCACGCTCACTGCCAAGGAGTTCGCCGTGCTGGAG
CAGCTGGCCCTGCGGGCGGGACGGGTGGTCAGCAAGGCGGACATCCTGGAACACGTCTGGGACTTCGCGTACGACGGGGA
CCCGAACATCGTCGAGGTGTACGTGAGCGCGCTGCGGCGCAAACTCTCCGCCTCGGCCATCCGTACGGTGCGCGGCGCCG
GCTACCGGCTGGAGGCGCTGTGA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (147-217)

• Response regulator receiver domain (Response_reg) (4-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	41.256	100	0.418
vicR	Streptococcus mutans UA159	38.362	100	0.405
covR	Lactococcus lactis subsp. lactis strain DGCC12653	39.819	100	0.4
covR	Streptococcus salivarius strain HSISS4	39.189	100	0.395
ciaR	Streptococcus pneumoniae D39	39.013	100	0.395
ciaR	Streptococcus pneumoniae Rx1	39.013	100	0.395
ciaR	Streptococcus pneumoniae R6	39.013	100	0.395
ciaR	Streptococcus pneumoniae TIGR4	39.013	100	0.395
micA	Streptococcus pneumoniae Cp1015	36.596	100	0.391