Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   MRS49_RS06335 Genome accession   NZ_CP094294
Coordinates   1215163..1215759 (+) Length   198 a.a.
NCBI ID   WP_003151513.1    Uniprot ID   I2CAH7
Organism   Bacillus velezensis strain AP3     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 1210163..1220759
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MRS49_RS06310 - 1210185..1210496 (+) 312 WP_007613966.1 hypothetical protein -
  MRS49_RS06320 - 1210838..1212307 (-) 1470 WP_032876285.1 glycoside hydrolase family 32 protein -
  MRS49_RS06325 - 1212322..1213554 (-) 1233 WP_007613980.1 MFS transporter -
  MRS49_RS06330 - 1213945..1214919 (+) 975 WP_032876282.1 LacI family DNA-binding transcriptional regulator -
  MRS49_RS06335 clpP 1215163..1215759 (+) 597 WP_003151513.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  MRS49_RS06340 pgmB 1215804..1216493 (-) 690 WP_032876279.1 beta-phosphoglucomutase -
  MRS49_RS06345 - 1216490..1218175 (-) 1686 WP_032876276.1 alpha-glucosidase -
  MRS49_RS06350 - 1218168..1220441 (-) 2274 WP_032876272.1 glycoside hydrolase family 65 protein -

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21831.06 Da        Isoelectric Point: 4.6982

>NTDB_id=668652 MRS49_RS06335 WP_003151513.1 1215163..1215759(+) (clpP) [Bacillus velezensis strain AP3]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLEAEDPEKDISIYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSADEALEYGLIDKVLTRNTEDQK

Nucleotide


Download         Length: 597 bp        

>NTDB_id=668652 MRS49_RS06335 WP_003151513.1 1215163..1215759(+) (clpP) [Bacillus velezensis strain AP3]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGAGAAAGAGCTTATGATATTTACTCCCGTCTTTTGAAGGA
CCGTATTATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCCTTGAAGCGG
AAGACCCTGAAAAAGATATTTCCATTTACATTAACAGCCCTGGCGGATCAATCACTGCCGGTATGGCAATCTATGATACA
ATGCAGTTCATTAAACCGAAAGTATCCACGATCTGCATCGGTATGGCCGCTTCTATGGGAGCATTTTTACTTGCAGCCGG
AGAAAAAGGCAAACGTTACGCGCTTCCTAACAGTGAAGTTATGATTCACCAGCCGCTTGGCGGAGCGCAAGGACAGGCGA
CAGAAATTGAAATCGCTGCAAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTGCTTGCTGAACGTACCGGCCAG
CCGCTTGAAGTCATTGAGCGCGATACAGACCGCGACAACTTCAAATCAGCTGATGAAGCCTTAGAATACGGCTTAATCGA
TAAAGTGCTGACACGCAATACAGAAGACCAGAAGTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2CAH7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

95.96

100

0.96
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

68.586

96.465

0.662
  clpP Streptococcus thermophilus LMG 18311

58.549

97.475

0.571
  clpP Streptococcus thermophilus LMD-9

58.549

97.475

0.571
  clpP Streptococcus pneumoniae D39

57.216

97.98

0.561
  clpP Streptococcus pneumoniae Rx1

57.216

97.98

0.561
  clpP Streptococcus pneumoniae R6

57.216

97.98

0.561
  clpP Streptococcus pneumoniae TIGR4

57.216

97.98

0.561
  clpP Lactococcus lactis subsp. cremoris KW2

56.701

97.98

0.556
  clpP Streptococcus pyogenes JRS4

55.44

97.475

0.54
  clpP Streptococcus pyogenes MGAS315

55.44

97.475

0.54
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

54.639

97.98

0.535
  clpP Streptococcus mutans UA159

54.639

97.98

0.535

Multiple sequence alignment