Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   MP387_RS05570 Genome accession   NZ_CP094226
Coordinates   1138581..1139231 (-) Length   216 a.a.
NCBI ID   WP_242745652.1    Uniprot ID   -
Organism   Streptococcus oralis strain 1648     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1133581..1144231
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP387_RS05550 (MP387_05550) rplT 1134963..1135322 (-) 360 WP_000124830.1 50S ribosomal protein L20 -
  MP387_RS05555 (MP387_05555) rpmI 1135374..1135574 (-) 201 WP_001125942.1 50S ribosomal protein L35 -
  MP387_RS05560 (MP387_05560) infC 1135607..1136137 (-) 531 WP_007521573.1 translation initiation factor IF-3 -
  MP387_RS05565 (MP387_05565) comEC/celB 1136357..1138597 (-) 2241 WP_242745650.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  MP387_RS05570 (MP387_05570) comEA/celA/cilE 1138581..1139231 (-) 651 WP_242745652.1 helix-hairpin-helix domain-containing protein Machinery gene
  MP387_RS05575 (MP387_05575) - 1139298..1139867 (-) 570 WP_242745654.1 GNAT family N-acetyltransferase -
  MP387_RS05580 (MP387_05580) ald 1140043..1141155 (+) 1113 WP_242745655.1 alanine dehydrogenase -
  MP387_RS05585 (MP387_05585) - 1141344..1143176 (-) 1833 WP_242745657.1 G5 domain-containing protein -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23132.32 Da        Isoelectric Point: 7.1712

>NTDB_id=668112 MP387_RS05570 WP_242745652.1 1138581..1139231(-) (comEA/celA/cilE) [Streptococcus oralis strain 1648]
MKAIIEKIKEYKILVICAGLGLALGGFFLLKPTSQTSVKESNLQAEVAAVSKDSSSEKEVKKEEKDESPEQDLITVDVKG
AVKSPGIYDLPVGSRVHDAVQKAGGLTEEADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTASGTTSSTSKDKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=668112 MP387_RS05570 WP_242745652.1 1138581..1139231(-) (comEA/celA/cilE) [Streptococcus oralis strain 1648]
ATGAAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCCTTGTCATTTGTGCTGGTTTAGGTTTGGCCTTGGGCGGATT
TTTCCTACTAAAGCCAACTTCACAAACATCTGTAAAAGAATCAAATTTGCAGGCTGAAGTCGCAGCTGTTTCAAAGGATT
CATCGTCTGAAAAAGAAGTGAAGAAGGAAGAAAAGGACGAGTCTCCTGAACAAGATTTGATTACGGTAGATGTCAAAGGT
GCTGTTAAATCGCCAGGGATTTATGATTTACCAGTAGGGAGTCGTGTTCATGATGCCGTTCAGAAGGCGGGTGGATTGAC
AGAGGAAGCAGATAGTAAGTCGCTCAATCTAGCACAGAAAGTCAGTGACGAGGCTCTTGTCTATGTTCCAACTAAGGGAG
AAGAAGCAGTGAGTCAGCAGACTGCCTCTGGAACGACTTCTTCGACAAGTAAAGATAAGAAGGTCAACCTAAATAAAGCT
AGTCTGGAAGAACTCAAGCAGGTCAAAGGCTTGGGAGGAAAACGAGCCCAGGATATTATCGATCATCGTGAGGCAAATGG
CAAGTTCAAGTCGGTTGATGAATTAAAGAAGGTCTCTGGTATTGGCGCTAAGACCATAGAAAAGCTAAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(152-214)

SLBB domain (SLBB)

(76-126)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

91.204

100

0.912
  comEA/celA/cilE Streptococcus mitis NCTC 12261

89.815

100

0.898
  comEA/celA/cilE Streptococcus pneumoniae D39

89.352

100

0.894
  comEA/celA/cilE Streptococcus pneumoniae R6

89.352

100

0.894
  comEA/celA/cilE Streptococcus pneumoniae Rx1

89.352

100

0.894
  comEA/celA/cilE Streptococcus mitis SK321

87.037

100

0.87
  comEA Lactococcus lactis subsp. cremoris KW2

43.478

100

0.463
  comEA Latilactobacillus sakei subsp. sakei 23K

33.476

100

0.361

Multiple sequence alignment