Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   MP387_RS05565 Genome accession   NZ_CP094226
Coordinates   1136357..1138597 (-) Length   746 a.a.
NCBI ID   WP_242745650.1    Uniprot ID   -
Organism   Streptococcus oralis strain 1648     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1131357..1143597
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP387_RS05545 (MP387_05545) - 1133123..1134787 (-) 1665 WP_242745648.1 molecular chaperone HscC -
  MP387_RS05550 (MP387_05550) rplT 1134963..1135322 (-) 360 WP_000124830.1 50S ribosomal protein L20 -
  MP387_RS05555 (MP387_05555) rpmI 1135374..1135574 (-) 201 WP_001125942.1 50S ribosomal protein L35 -
  MP387_RS05560 (MP387_05560) infC 1135607..1136137 (-) 531 WP_007521573.1 translation initiation factor IF-3 -
  MP387_RS05565 (MP387_05565) comEC/celB 1136357..1138597 (-) 2241 WP_242745650.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  MP387_RS05570 (MP387_05570) comEA/celA/cilE 1138581..1139231 (-) 651 WP_242745652.1 helix-hairpin-helix domain-containing protein Machinery gene
  MP387_RS05575 (MP387_05575) - 1139298..1139867 (-) 570 WP_242745654.1 GNAT family N-acetyltransferase -
  MP387_RS05580 (MP387_05580) ald 1140043..1141155 (+) 1113 WP_242745655.1 alanine dehydrogenase -
  MP387_RS05585 (MP387_05585) - 1141344..1143176 (-) 1833 WP_242745657.1 G5 domain-containing protein -

Sequence

Protein


Download         Length: 746 a.a.        Molecular weight: 84715.83 Da        Isoelectric Point: 8.7008

>NTDB_id=668111 MP387_RS05565 WP_242745650.1 1136357..1138597(-) (comEC/celB) [Streptococcus oralis strain 1648]
MLQWIKNFPIPLIYLSFLLLWLYYAIFGASYLALLGFVFLLVCLFFQFSWKSAGKVLAICGVFGFWFLFQTWQQTQASQN
LVDSVERVRILPDTIKVNGDSLSFRGKAEGRTFQVYYKLQSEEEKEQFQTLTDLHEIELEGKLSEPEGQRNFGGFDYQAY
LKTQGIYQTLTIKSIQSMKKISSWDIGENLSSLRRKAVVWIKMHFPDSMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDAFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLSQHGVKGLDNFALTILVLFII
MPNFFLTAGGVLSCAYAFILTMTSKEGDGLKAVARESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDVVFLPLLSI
LFILSFIYPVTQFNFVFEWLEGVIRLVSQLASRPLVLGQPTTWLLILLLVSLALVYDMRKNIKRLAVFSLFIVGLFILTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESDKKIEAWQEKSTTSNAQRTLIPYLKSRGVDKIDQLILTNTDK
EHVGDLLEVTKAFHVGEILVSKGSLTQKEFVAGLEASQNKVRSVTAGEYFPIFGSYLELLSPRQIGDGDRDDSLVLYGKL
LDKHFLFTGNLKEKGEKDLLKQYPDLEVDVLKAGQHGAKTSSNSAFLEQLKPEFTLISVGKSNRAKLPHQETLTQLENIK
SKIYRTDQQGAIRFKGWNSWRIETVR

Nucleotide


Download         Length: 2241 bp        

>NTDB_id=668111 MP387_RS05565 WP_242745650.1 1136357..1138597(-) (comEC/celB) [Streptococcus oralis strain 1648]
ATGTTACAGTGGATTAAGAATTTCCCTATTCCTCTAATCTATCTGAGCTTTCTGTTGCTCTGGCTTTACTATGCCATTTT
TGGAGCGTCCTATCTCGCACTGCTAGGTTTTGTTTTTTTGCTCGTCTGTCTCTTTTTTCAATTTTCTTGGAAATCTGCTG
GAAAAGTTCTAGCGATTTGTGGAGTTTTTGGATTTTGGTTTCTGTTTCAAACTTGGCAACAGACACAAGCTAGTCAAAAC
CTAGTGGATTCTGTTGAAAGGGTACGGATTTTACCAGATACCATCAAAGTCAATGGAGACAGTCTGTCCTTTCGGGGCAA
GGCTGAGGGCCGCACCTTCCAAGTTTACTATAAACTCCAGTCCGAGGAGGAGAAAGAGCAATTTCAAACCTTGACAGACC
TTCATGAGATAGAACTAGAAGGAAAACTTTCCGAGCCAGAAGGCCAGAGAAATTTTGGTGGCTTTGACTACCAAGCCTAT
CTGAAAACTCAGGGGATTTACCAAACTTTGACTATCAAGAGTATCCAGTCAATGAAAAAGATTAGCAGTTGGGATATAGG
AGAAAATCTGTCCAGTTTACGTCGAAAGGCTGTCGTTTGGATCAAGATGCACTTTCCAGATTCTATGCGCAATTATATGA
CAGGTCTTCTTTTAGGACATTTGGACACGGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTTGGAATTATCCATCTC
TTTGCCTTGTCGGGTATGCAAGTGGGCTTCTTTATGGATGCCTTTAAGAAACTCCTCTTACGATTGGGCTTGACCCAAGA
AAAGTTGAAGTGGCTGACCTATCCCTTTTCCCTTATCTATGCAGGTCTGACAGGATTTTCAGCTTCGGTCATTCGCAGTC
TCTTGCAAAAGTTACTATCCCAACATGGTGTTAAAGGTTTGGATAATTTTGCCTTGACGATCCTTGTCCTTTTTATCATT
ATGCCCAACTTTTTCCTAACTGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCTTGACCATGACTAGCAAAGAAGG
CGATGGGCTCAAGGCTGTTGCCAGAGAAAGTTTGGTCATTTCTTTGGGAATATTGCCCATTCTATCCTTCTATTTTGCAG
AATTTCAGCCTTGGTCTATTCTTTTGACCTTTGTTTTTTCCTTTCTGTTTGATGTGGTATTCTTACCGCTTTTGTCCATC
TTATTCATTCTGTCTTTTATTTACCCAGTCACTCAGTTTAACTTTGTCTTTGAGTGGTTAGAGGGCGTCATTCGCTTGGT
ATCGCAGCTGGCAAGTAGGCCCCTGGTCCTTGGTCAACCCACCACATGGCTGTTGATTCTCCTCTTAGTTTCATTAGCCT
TGGTCTATGATATGAGGAAAAACATTAAAAGACTAGCAGTATTCAGTCTCTTTATTGTGGGGCTCTTTATCTTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTGACTGGGAAAAC
TATTCTCATAGATGTAGGTGGTAAGGCAGAATCTGATAAGAAAATCGAGGCTTGGCAAGAAAAGTCGACGACCAGCAATG
CCCAGAGAACCTTGATTCCCTATCTTAAAAGTCGAGGAGTAGACAAGATTGACCAGCTGATTTTGACAAATACAGATAAG
GAGCATGTTGGTGATTTACTGGAGGTGACCAAGGCTTTCCATGTCGGGGAGATTTTAGTATCAAAAGGAAGTCTGACACA
GAAGGAATTTGTAGCGGGACTAGAAGCAAGTCAAAACAAGGTACGTAGTGTGACAGCTGGGGAGTATTTCCCGATTTTTG
GCAGTTACTTAGAACTTCTATCTCCAAGGCAGATTGGAGATGGGGACCGTGATGATTCTCTGGTTCTTTATGGAAAACTT
TTGGATAAGCACTTTCTCTTCACAGGAAATTTGAAAGAGAAGGGAGAGAAGGATCTTCTAAAGCAATACCCTGACTTAGA
GGTGGATGTCCTGAAAGCAGGCCAACATGGTGCTAAAACATCATCCAATTCAGCTTTCCTAGAACAGCTCAAACCTGAGT
TCACTCTCATTTCAGTTGGAAAGAGCAATCGAGCAAAACTCCCTCATCAGGAAACCTTGACACAACTGGAAAATATCAAG
AGTAAGATTTACAGAACTGACCAGCAAGGGGCTATCCGCTTTAAAGGATGGAATAGTTGGAGAATTGAAACGGTTCGATA
A

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(31-176)

Metallo-beta-lactamase superfamily (Lactamase_B)

(492-631)

Competence protein (Competence)

(216-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

88.74

100

0.887
  comEC/celB Streptococcus mitis NCTC 12261

87.785

99.866

0.877
  comEC/celB Streptococcus pneumoniae TIGR4

86.461

100

0.865
  comEC/celB Streptococcus pneumoniae D39

86.327

100

0.863
  comEC/celB Streptococcus pneumoniae Rx1

86.327

100

0.863
  comEC/celB Streptococcus pneumoniae R6

86.327

100

0.863
  comEC Lactococcus lactis subsp. cremoris KW2

44.939

99.33

0.446

Multiple sequence alignment