NTDB

Overview

Name	clpP	Type	Regulator
Locus tag	MK860_RS16310	Genome accession	NZ_CP092829
Coordinates	3176583..3177179 (+)	Length	198 a.a.
NCBI ID	WP_003212962.1	Uniprot ID	A0A081LFM4
Organism	Bacillus pumilus strain MS32
Function	degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3171583..3182179

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MK860_RS16290 (MK860_16225)	abc-f	3171621..3173180 (-)	1560	WP_278179613.1	ABC-F type ribosomal protection protein	-
MK860_RS16295 (MK860_16230)	-	3173672..3174841 (-)	1170	WP_044139005.1	macrolide family glycosyltransferase	-
MK860_RS16300 (MK860_16235)	-	3175010..3175900 (-)	891	WP_260564454.1	ABC transporter substrate-binding protein	-
MK860_RS16310 (MK860_16245)	clpP	3176583..3177179 (+)	597	WP_003212962.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
MK860_RS16315 (MK860_16250)	-	3177239..3177817 (-)	579	WP_044139006.1	TIGR00730 family Rossman fold protein	-
MK860_RS16320 (MK860_16255)	-	3177954..3178270 (+)	317	Protein_3157	MazG-like family protein	-
MK860_RS16325 (MK860_16260)	-	3178310..3179932 (-)	1623	WP_106066199.1	SulP family inorganic anion transporter	-
MK860_RS16330 (MK860_16265)	-	3179970..3180551 (-)	582	WP_065097977.1	carbonic anhydrase	-
MK860_RS16335 (MK860_16270)	-	3181103..3182080 (+)	978	WP_065097976.1	D-glycerate dehydrogenase	-

Sequence

Protein

Download Length: 198 a.a. Molecular weight: 21816.00 Da Isoelectric Point: 4.6905

                                >NTDB_id=660616 MK860_RS16310 WP_003212962.1 3176583..3177179(+) (clpP) [Bacillus pumilus strain MS32]

MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLEAEDPEKDISIYINSPGGSITAGMAIYDT

MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILSLRDKLNQVLAERTGQ

PIEVIERDTDRDNFKTAEEALQYGLIDKVLTRNAEEQK

Nucleotide

Download Length: 597 bp

                                >NTDB_id=660616 MK860_RS16310 WP_003212962.1 3176583..3177179(+) (clpP) [Bacillus pumilus strain MS32]

ATGAATTTAATACCTACAGTCATTGAGCAAACAAATCGTGGGGAAAGAGCTTACGACATTTATTCTCGTCTTTTAAAAGA

CCGTATTATCATGCTTGGTTCTGCGATCGATGACAATGTTGCCAACTCCATCGTGTCACAGCTGCTTTTCTTAGAAGCTG

AAGATCCAGAAAAAGATATTTCTATCTACATTAACAGCCCTGGCGGTTCAATCACAGCTGGTATGGCCATTTACGATACG

ATGCAATTTATTAAACCAAAGGTATCAACCATTTGTATTGGTATGGCTGCATCTATGGGTGCGTTCCTGCTTGCTGCTGG

TGAAAAAGGTAAGCGTTATGCTCTTCCAAACAGTGAAGTCATGATTCACCAACCACTAGGTGGTGCCCAAGGTCAAGCAA

CAGAAATTGAAATTGCGGCAAAACGAATCCTTTCTTTACGCGATAAACTGAACCAAGTACTTGCTGAACGTACTGGTCAG

CCAATCGAAGTGATTGAGCGCGATACAGATCGTGACAACTTCAAAACAGCAGAAGAAGCACTTCAATACGGACTCATTGA

CAAAGTCTTGACCCGTAATGCAGAAGAACAAAAATAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A081LFM4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
clpP	Bacillus subtilis subsp. subtilis str. 168	92.386	99.495	0.919
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	67.539	96.465	0.652
clpP	Streptococcus thermophilus LMG 18311	58.549	97.475	0.571
clpP	Streptococcus thermophilus LMD-9	58.549	97.475	0.571
clpP	Lactococcus lactis subsp. cremoris KW2	56.186	97.98	0.551
clpP	Streptococcus pneumoniae Rx1	55.67	97.98	0.545
clpP	Streptococcus pneumoniae D39	55.67	97.98	0.545
clpP	Streptococcus pneumoniae R6	55.67	97.98	0.545
clpP	Streptococcus pneumoniae TIGR4	55.67	97.98	0.545
clpP	Streptococcus pyogenes JRS4	55.44	97.475	0.54
clpP	Streptococcus pyogenes MGAS315	55.44	97.475	0.54
clpP	Streptococcus mutans UA159	54.639	97.98	0.535
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	54.124	97.98	0.53

Detailed information NTG0660616