Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG537_RS33690 Genome accession   NZ_CP108102
Coordinates   7558279..7558920 (+) Length   213 a.a.
NCBI ID   WP_266767280.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00228     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7553279..7563920
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG537_RS33670 (OG537_33640) - 7554124..7554879 (-) 756 WP_328832307.1 transglycosylase SLT domain-containing protein -
  OG537_RS33675 (OG537_33645) - 7555178..7556263 (-) 1086 WP_328934546.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OG537_RS33680 (OG537_33650) - 7556260..7556955 (-) 696 WP_328934547.1 SDR family NAD(P)-dependent oxidoreductase -
  OG537_RS33685 (OG537_33655) - 7557141..7558286 (+) 1146 WP_328934548.1 GAF domain-containing sensor histidine kinase -
  OG537_RS33690 (OG537_33660) vraR 7558279..7558920 (+) 642 WP_266767280.1 response regulator transcription factor Regulator
  OG537_RS33695 (OG537_33665) - 7559101..7559340 (+) 240 WP_266767279.1 chaplin -
  OG537_RS33700 (OG537_33670) - 7559555..7559794 (+) 240 WP_266767278.1 chaplin family protein -
  OG537_RS33705 (OG537_33675) - 7560055..7560843 (-) 789 WP_328934549.1 hypothetical protein -
  OG537_RS33710 (OG537_33680) - 7560976..7561767 (+) 792 WP_200690084.1 ABC transporter ATP-binding protein -
  OG537_RS33715 (OG537_33685) - 7561844..7562278 (+) 435 WP_328832313.1 NfeD family protein -
  OG537_RS33720 (OG537_33690) - 7562431..7563396 (+) 966 WP_266767274.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23112.51 Da        Isoelectric Point: 5.3797

>NTDB_id=653795 OG537_RS33690 WP_266767280.1 7558279..7558920(+) (vraR) [Streptomyces sp. NBC_00228]
MADPIKVLIVDDHQVVRRGLRTFLEVQDDIEVVGEAADGAEGVARTEELKPDVVLMDVKMPGMDGIDALRRLRELDLPAR
VLIVTSFTEQRTVIPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVAGVLLSQEESNSGQGRGGSLTEREREVL
GLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALFAVRHGLTR

Nucleotide


Download         Length: 642 bp        

>NTDB_id=653795 OG537_RS33690 WP_266767280.1 7558279..7558920(+) (vraR) [Streptomyces sp. NBC_00228]
GTGGCTGATCCGATCAAGGTCCTCATCGTCGACGACCACCAGGTCGTCCGCCGGGGCCTGCGCACCTTCCTGGAGGTGCA
GGACGACATCGAGGTCGTCGGCGAGGCGGCCGACGGCGCCGAAGGAGTCGCCCGCACCGAGGAGCTCAAGCCCGACGTCG
TCCTCATGGACGTCAAGATGCCGGGCATGGACGGCATCGACGCGCTGCGCAGACTCCGCGAACTCGACCTCCCCGCGCGC
GTGTTGATCGTCACCAGCTTCACCGAACAGCGCACGGTGATCCCGGCCCTGCGCGCGGGCGCCGCCGGTTACGTCTACAA
GGACGTGGACCCGGACGCCCTGGCCGGCGCCATCCGTTCCGTGCACGCGGGCCACATCCTGCTCCAACCCGAGGTCGCCG
GCGTCCTGTTGTCCCAGGAGGAGTCCAATTCGGGTCAGGGGAGAGGCGGTTCGCTCACGGAGCGGGAGCGCGAGGTGCTC
GGCCTGATCGCCGACGGCCGCTCCAACCGCGAGATAGCCCGCGCCCTGGTGCTCTCCGAGAAGACGGTCAAGACCCACGT
CTCGAACATCCTGATGAAGCTCGACCTGGCGGACCGCACCCAGGCCGCCCTGTTCGCCGTACGCCACGGTCTGACGCGGT
GA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(151-206)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.948

100

0.469
  degU Bacillus subtilis subsp. subtilis str. 168

38.288

100

0.399