Detailed information NTG0064986

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: H020_RS14610
• Genome accession: NZ_AKVY01000001
• Coordinates: 512777..513364 (-)
• Length: 195 a.a.
• NCBI ID: WP_000205166.1
• Uniprot ID: Q9ETN5
• Organism: Streptococcus pneumoniae TIGR4
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 507777..518364

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H020_RS0102575	-	508239..509579 (+)	1341	WP_001017646.1	sensor histidine kinase	-
H020_RS0102580	blpC	509650..509778 (-)	129	WP_000358815.1	quorum-sensing system pheromone BlpC	-
H020_RS0102585	-	509835..511196 (-)	1362	WP_001069075.1	bacteriocin secretion accessory protein	-
H020_RS14600	comA/nlmT	511207..511854 (-)	648	WP_078064020.1	ATP-binding cassette domain-containing protein	Regulator
H020_RS14605	comA/nlmT	511870..512883 (-)	1014	WP_307772067.1	ABC transporter transmembrane domain-containing protein	Regulator
H020_RS14610	comA/nlmT	512777..513364 (-)	588	WP_000205166.1	cysteine peptidase family C39 domain-containing protein	Regulator
H020_RS0102605	blpI	513646..513843 (+)	198	WP_001093259.1	bacteriocin-like peptide BlpI	-
H020_RS0102610	blpJ	514310..514579 (+)	270	WP_001093248.1	bacteriocin-like peptide BlpJ	-
H020_RS0102615	blpU	514648..514878 (+)	231	WP_000379967.1	bacteriocin-like peptide BlpU	-
H020_RS0102620	-	514881..515000 (+)	120	WP_000346296.1	PncF family bacteriocin immunity protein	-
H020_RS12495	-	515297..515461 (+)	165	WP_000727118.1	hypothetical protein	-
H020_RS0102635	-	515458..515862 (+)	405	WP_000846943.1	hypothetical protein	-
H020_RS12500	-	516065..516869 (+)	805	WP_100214365.1	IS5 family transposase	-
H020_RS0102650	blpM	517019..517273 (+)	255	WP_000379879.1	two-peptide bacteriocin subunit BlpM	-
H020_RS0102655	blpN	517289..517492 (+)	204	WP_001099492.1	two-peptide bacteriocin subunit BlpN	-
H020_RS0102660	cipB	517736..517885 (+)	150	WP_001818346.1	bacteriocin-like peptide BlpO	Regulator
H020_RS0102665	-	517989..518108 (+)	120	WP_000346296.1	PncF family bacteriocin immunity protein	-

Sequence

Protein

• Length: 195 a.a.
• Molecular weight: 22270.71 Da
• Isoelectric Point: 9.6188

>NTDB_id=64986 H020_RS14610 WP_000205166.1 512777..513364(-) (comA/nlmT) [Streptococcus pneumoniae TIGR4]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide

• Length: 588 bp

>NTDB_id=64986 H020_RS14610 WP_000205166.1 512777..513364(-) (comA/nlmT) [Streptococcus pneumoniae TIGR4]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

3D structure

• AlphaFold DB: Q9ETN5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	59.89	93.333	0.559
comA	Streptococcus mitis NCTC 12261	54.891	94.359	0.518
comA	Streptococcus mitis SK321	54.348	94.359	0.513
comA	Streptococcus pneumoniae TIGR4	53.804	94.359	0.508
comA	Streptococcus pneumoniae Rx1	53.804	94.359	0.508
comA	Streptococcus pneumoniae D39	53.804	94.359	0.508
comA	Streptococcus pneumoniae R6	53.804	94.359	0.508
comA	Streptococcus gordonii str. Challis substr. CH1	52.717	94.359	0.497