Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   H020_RS14605 Genome accession   NZ_AKVY01000001
Coordinates   511870..512883 (-) Length   337 a.a.
NCBI ID   WP_307772067.1    Uniprot ID   -
Organism   Streptococcus pneumoniae TIGR4     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 506870..517883
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H020_RS0102565 - 507145..507483 (+) 339 WP_000876675.1 LytTR family DNA-binding domain-containing protein -
  H020_RS0102570 comE/blpR 507488..508225 (+) 738 WP_001219120.1 response regulator transcription factor Regulator
  H020_RS0102575 - 508239..509579 (+) 1341 WP_001017646.1 sensor histidine kinase -
  H020_RS0102580 blpC 509650..509778 (-) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  H020_RS0102585 - 509835..511196 (-) 1362 WP_001069075.1 bacteriocin secretion accessory protein -
  H020_RS14600 comA/nlmT 511207..511854 (-) 648 WP_078064020.1 ATP-binding cassette domain-containing protein Regulator
  H020_RS14605 comA/nlmT 511870..512883 (-) 1014 WP_307772067.1 ABC transporter transmembrane domain-containing protein Regulator
  H020_RS14610 comA/nlmT 512777..513364 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  H020_RS0102605 blpI 513646..513843 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  H020_RS0102610 blpJ 514310..514579 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  H020_RS0102615 blpU 514648..514878 (+) 231 WP_000379967.1 bacteriocin-like peptide BlpU -
  H020_RS0102620 - 514881..515000 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  H020_RS12495 - 515297..515461 (+) 165 WP_000727118.1 hypothetical protein -
  H020_RS0102635 - 515458..515862 (+) 405 WP_000846943.1 hypothetical protein -
  H020_RS12500 - 516065..516869 (+) 805 WP_100214365.1 IS5 family transposase -
  H020_RS0102650 blpM 517019..517273 (+) 255 WP_000379879.1 two-peptide bacteriocin subunit BlpM -
  H020_RS0102655 blpN 517289..517492 (+) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -

Sequence

Protein


Download         Length: 337 a.a.        Molecular weight: 38280.73 Da        Isoelectric Point: 5.1196

>NTDB_id=64985 H020_RS14605 WP_307772067.1 511870..512883(-) (comA/nlmT) [Streptococcus pneumoniae TIGR4]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFG

Nucleotide


Download         Length: 1014 bp        

>NTDB_id=64985 H020_RS14605 WP_307772067.1 511870..512883(-) (comA/nlmT) [Streptococcus pneumoniae TIGR4]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGTCAGAGATTAAGTATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGATTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGAGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGATGA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.997

100

0.73
  comA Streptococcus gordonii str. Challis substr. CH1

67.16

100

0.674
  comA Streptococcus mitis NCTC 12261

66.766

100

0.668
  comA Streptococcus pneumoniae Rx1

66.469

100

0.665
  comA Streptococcus pneumoniae D39

66.469

100

0.665
  comA Streptococcus pneumoniae R6

66.469

100

0.665
  comA Streptococcus pneumoniae TIGR4

66.172

100

0.662
  comA Streptococcus mitis SK321

66.172

100

0.662

Multiple sequence alignment