Detailed information NTG0064807

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: SRA_RS01760
• Genome accession: NZ_AJTZ01000004
• Coordinates: 24706..25620 (-)
• Length: 304 a.a.
• NCBI ID: WP_003090542.1
• Uniprot ID: -
• Organism: Streptococcus ratti FA-1 = DSM 20564 strain FA-1
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 19706..30620

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SRA_RS01740 (SRA_01799)	-	20679..22463 (-)	1785	WP_003086923.1	acyltransferase family protein	-
SRA_RS01745 (SRA_01804)	-	22460..22840 (-)	381	WP_003090541.1	hypothetical protein	-
SRA_RS01750 (SRA_01809)	-	22907..23329 (-)	423	WP_003086927.1	low molecular weight protein-tyrosine-phosphatase	-
SRA_RS01755 (SRA_01814)	ruvB	23360..24361 (-)	1002	WP_003086929.1	Holliday junction branch migration DNA helicase RuvB	-
-	comS	24587..24637 (-)	51	-	-	Regulator
SRA_RS01760 (SRA_01824)	comR	24706..25620 (-)	915	WP_003090542.1	helix-turn-helix domain-containing protein	Regulator
SRA_RS01765 (SRA_01829)	purB	25761..27059 (-)	1299	WP_003086936.1	adenylosuccinate lyase	-
SRA_RS01770 (SRA_01834)	-	27063..27860 (-)	798	WP_225310761.1	hypothetical protein	-
SRA_RS10510	-	27883..27936 (-)	54	WP_162129578.1	hypothetical protein	-
SRA_RS01775 (SRA_01839)	-	27938..28339 (-)	402	WP_003086941.1	SRPBCC family protein	-
SRA_RS01780 (SRA_01844)	-	28372..28983 (-)	612	WP_003086942.1	CPBP family intramembrane glutamic endopeptidase	-
SRA_RS01785 (SRA_01849)	-	29048..29740 (-)	693	WP_003086943.1	aspartate/glutamate racemase family protein	-
SRA_RS01790 (SRA_01854)	-	29751..30500 (-)	750	WP_003086944.1	hypothetical protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 36059.40 Da
• Isoelectric Point: 4.6051

>NTDB_id=64807 SRA_RS01760 WP_003090542.1 24706..25620(-) (comR) [Streptococcus ratti FA-1 = DSM 20564 strain FA-1]
MLEDFGERVKRLRLEKGLTKEVFCQDESELSMRQLTRIESGESVPTLRKAVYIAERLGVTLDYLTDGRNIDLPNRYKELK
YLLLRTPTYGDQEKLAEREVYFDEIFNHFYDTLPEEEQLVIDALQSKLDIHLSQNIDFGVGILNDYFDQILMRKRYQVND
LIIIDLYFSCLTISDLRMDIFDLDKYHKLMQVLLKQSDYLPVEDLFVLNNVLLNNFGILLLLEKYDIIKELIAVANDIMV
RTSDFQKKPIVSILEWKYYLLAENNEAEARKSYDSAILFAKLTENTTLREKLEREWQKDYQNRT

Nucleotide

• Length: 915 bp

>NTDB_id=64807 SRA_RS01760 WP_003090542.1 24706..25620(-) (comR) [Streptococcus ratti FA-1 = DSM 20564 strain FA-1]
ATTTTAGAAGATTTTGGGGAGAGAGTAAAACGTCTGCGGTTAGAAAAGGGACTGACCAAAGAAGTTTTCTGTCAAGATGA
GTCTGAGCTGTCTATGCGGCAGCTGACAAGGATTGAGTCGGGGGAATCAGTGCCTACGCTCAGAAAGGCTGTTTATATTG
CTGAGCGCTTAGGTGTAACACTGGATTATCTGACGGATGGAAGAAATATTGATCTGCCGAACCGTTACAAGGAACTGAAA
TATCTGTTGCTGAGAACACCGACCTACGGCGATCAGGAAAAGCTGGCTGAAAGGGAGGTTTATTTTGATGAGATTTTTAA
TCATTTTTATGACACCCTGCCTGAGGAAGAGCAGCTTGTGATTGATGCTCTTCAGTCAAAATTAGATATTCATTTGAGCC
AAAATATTGATTTTGGGGTCGGAATTTTAAACGATTACTTTGATCAGATTTTAATGCGCAAACGCTATCAGGTGAATGAT
TTAATCATCATTGATCTTTATTTTTCCTGCCTAACGATCAGTGATTTACGTATGGATATTTTTGATTTGGATAAGTATCA
TAAGCTGATGCAGGTCCTTTTAAAACAGAGTGATTACCTGCCCGTGGAAGATTTATTTGTGCTGAATAACGTTTTATTAA
ATAATTTTGGCATTCTCCTTCTTTTAGAAAAATATGACATTATCAAGGAGCTGATTGCAGTTGCCAATGATATCATGGTA
AGGACCTCTGATTTTCAAAAGAAACCCATTGTCAGTATACTTGAATGGAAGTATTATCTGTTGGCAGAGAATAATGAAGC
AGAAGCAAGAAAAAGCTATGACTCGGCTATTTTGTTTGCGAAATTAACTGAAAATACCACATTAAGAGAAAAGTTAGAAA
GAGAGTGGCAGAAGGACTACCAAAACAGGACATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (9-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	74.013	100	0.74
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	50.347	94.737	0.477
comR	Streptococcus pyogenes MGAS315	45.485	98.355	0.447
comR	Streptococcus pyogenes MGAS8232	44.04	99.342	0.438
comR	Streptococcus suis P1/7	43.813	98.355	0.431
comR	Streptococcus suis 05ZYH33	43.813	98.355	0.431
comR	Streptococcus suis D9	40.532	99.013	0.401