Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   SCAZ3_RS09905 Genome accession   NZ_AIDX01000001
Coordinates   2044244..2044918 (+) Length   224 a.a.
NCBI ID   WP_003048303.1    Uniprot ID   A0A2D4DMP2
Organism   Streptococcus canis FSL Z3-227     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 2039244..2049918
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCAZ3_RS09890 (SCAZ3_05580) pstB 2039808..2040566 (+) 759 WP_003048297.1 phosphate ABC transporter ATP-binding protein PstB -
  SCAZ3_RS09895 (SCAZ3_05585) phoU 2040645..2041298 (+) 654 WP_003048299.1 phosphate signaling complex protein PhoU -
  SCAZ3_RS09900 (SCAZ3_05590) - 2041504..2044041 (+) 2538 WP_003048301.1 M1 family metallopeptidase -
  SCAZ3_RS09905 (SCAZ3_05595) ciaR 2044244..2044918 (+) 675 WP_003048303.1 response regulator transcription factor Regulator
  SCAZ3_RS09910 (SCAZ3_05600) ciaH 2044911..2046221 (+) 1311 WP_003048304.1 sensor histidine kinase Regulator
  SCAZ3_RS09915 (SCAZ3_05605) rpsT 2046667..2046915 (-) 249 WP_009881183.1 30S ribosomal protein S20 -
  SCAZ3_RS09920 (SCAZ3_05610) coaA 2046969..2047889 (-) 921 WP_003048306.1 type I pantothenate kinase -
  SCAZ3_RS09925 (SCAZ3_05615) - 2048157..2048756 (+) 600 WP_003048308.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25693.73 Da        Isoelectric Point: 4.4740

>NTDB_id=64803 SCAZ3_RS09905 WP_003048303.1 2044244..2044918(+) (ciaR) [Streptococcus canis FSL Z3-227]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KESIDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFTDKNLSFGNVVVDLRRKEVQVDGEPIELLGKEFDLLVY
ILQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTGFVDKLQTLRSVGYILKNNE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=64803 SCAZ3_RS09905 WP_003048303.1 2044244..2044918(+) (ciaR) [Streptococcus canis FSL Z3-227]
ATGATAAAAATATTATTAGTAGAAGATGACTTGAGTTTATCGAATTCCATTTTTGATTTTTTAGATGATTTTGCAGACGT
GATGCAAGTTTTTGATGGCGATGAAGGCTTATATGAAGCAGAAAGTGGTATTTATGATTTGATTTTGTTAGATCTCATGT
TACCAGAAAAAAATGGCTTTCAAGTCTTAAAAGAATTGCGGGAAAAAGATATTAAAATTCCAGTTTTGATTATGACAGCC
AAAGAAAGCATAGATGATAAGGGACATGGGTTTGAACTAGGAGCAGATGATTATCTAACCAAGCCGTTTTACCTTGAAGA
ATTAAAGATGCGCATCCAGGCCCTGTTAAAACGTACGGGCAAATTCACTGATAAAAATCTAAGTTTTGGTAATGTGGTGG
TGGATTTAAGACGAAAAGAAGTTCAAGTCGATGGGGAACCCATTGAGCTATTAGGAAAAGAGTTCGACTTATTGGTTTAC
ATATTGCAAAACCAAAATGTGATCTTACCCAAGACCCAAATTTTTGATCGCTTATGGGGGTTTGACAGCGACACGACAAT
CTCAGTTGTAGAGGTTTATGTCTCTAAAATTAGAAAAAAATTAAAAGGTACTGGTTTTGTTGATAAACTCCAAACCCTGA
GAAGTGTAGGTTATATTCTAAAAAACAATGAGTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2D4DMP2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

84.685

99.107

0.839
  ciaR Streptococcus pneumoniae D39

84.685

99.107

0.839
  ciaR Streptococcus pneumoniae R6

84.685

99.107

0.839
  ciaR Streptococcus pneumoniae TIGR4

84.685

99.107

0.839
  ciaR Streptococcus mutans UA159

83.333

99.107

0.826
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.222

100

0.384
  covR Streptococcus salivarius strain HSISS4

36.726

100

0.371
  micA Streptococcus pneumoniae Cp1015

34.615

100

0.362
  vicR Streptococcus mutans UA159

34.615

100

0.362

Multiple sequence alignment