Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   L1A18_RS09575 Genome accession   NZ_CP090887
Coordinates   1861233..1862249 (-) Length   338 a.a.
NCBI ID   WP_074017570.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NP7536     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1856233..1867249
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A18_RS10695 - 1856310..1856441 (-) 132 WP_000768904.1 hypothetical protein -
  L1A18_RS09535 (L1A18_09535) - 1856442..1857632 (-) 1191 WP_000167765.1 acetate kinase -
  L1A18_RS09540 (L1A18_09540) comYH 1857683..1858636 (-) 954 WP_000345099.1 class I SAM-dependent methyltransferase Machinery gene
  L1A18_RS09545 (L1A18_09545) - 1858697..1859291 (-) 595 Protein_1870 methyltransferase domain-containing protein -
  L1A18_RS09550 (L1A18_09550) comGG/cglG 1859428..1859841 (-) 414 WP_000265624.1 competence type IV pilus minor pilin ComGG Machinery gene
  L1A18_RS09555 (L1A18_09555) comGF/cglF 1859819..1860280 (-) 462 WP_000250542.1 competence type IV pilus minor pilin ComGF Machinery gene
  L1A18_RS09560 (L1A18_09560) comGE/cglE 1860243..1860545 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  L1A18_RS09565 (L1A18_09565) comGD/cglD 1860508..1860912 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  L1A18_RS09570 (L1A18_09570) comGC/cglC 1860905..1861231 (-) 327 WP_000738636.1 comG operon protein ComGC Machinery gene
  L1A18_RS09575 (L1A18_09575) comGB/cglB 1861233..1862249 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  L1A18_RS09580 (L1A18_09580) comGA/cglA/cilD 1862197..1863138 (-) 942 WP_000249552.1 competence type IV pilus ATPase ComGA Machinery gene
  L1A18_RS09585 (L1A18_09585) - 1863214..1863579 (-) 366 WP_000286415.1 DUF1033 family protein -
  L1A18_RS09590 (L1A18_09590) - 1863730..1864788 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  L1A18_RS09595 (L1A18_09595) nagA 1864951..1866102 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38482.48 Da        Isoelectric Point: 9.6162

>NTDB_id=646010 L1A18_RS09575 WP_074017570.1 1861233..1862249(-) (comGB/cglB) [Streptococcus pneumoniae strain NP7536]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=646010 L1A18_RS09575 WP_074017570.1 1861233..1862249(-) (comGB/cglB) [Streptococcus pneumoniae strain NP7536]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATAGGAGTTCCTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGTACAGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTACCATT
GTCACTCAGTTATCTCTAGCTGAAGTTCATGGCAATCTTCACCTGAGTTTGGGAAAGATAGAAGAATATCTAGACAATCT
GGCCAAGGTCAAGAAAAAGTTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

98.521

100

0.985
  comGB/cglB Streptococcus pneumoniae D39

98.521

100

0.985
  comGB/cglB Streptococcus pneumoniae R6

98.521

100

0.985
  comGB/cglB Streptococcus pneumoniae TIGR4

98.521

100

0.985
  comGB/cglB Streptococcus mitis SK321

94.97

100

0.95
  comGB/cglB Streptococcus mitis NCTC 12261

94.083

100

0.941
  comYB Streptococcus gordonii str. Challis substr. CH1

70.536

99.408

0.701
  comYB Streptococcus mutans UA140

58.176

94.083

0.547
  comYB Streptococcus mutans UA159

58.176

94.083

0.547
  comGB Lactococcus lactis subsp. cremoris KW2

50.898

98.817

0.503