Detailed information NTG0646006

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: L1A18_RS09555
• Genome accession: NZ_CP090887
• Coordinates: 1859819..1860280 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250542.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain NP7536
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1854819..1865280

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L1A18_RS09525 (L1A18_09525)	-	1855123..1855947 (-)	825	WP_001809383.1	membrane protein insertase YidC	-
L1A18_RS09530 (L1A18_09530)	rnpA	1855922..1856293 (-)	372	WP_000739244.1	ribonuclease P protein component	-
L1A18_RS10695	-	1856310..1856441 (-)	132	WP_000768904.1	hypothetical protein	-
L1A18_RS09535 (L1A18_09535)	-	1856442..1857632 (-)	1191	WP_000167765.1	acetate kinase	-
L1A18_RS09540 (L1A18_09540)	comYH	1857683..1858636 (-)	954	WP_000345099.1	class I SAM-dependent methyltransferase	Machinery gene
L1A18_RS09545 (L1A18_09545)	-	1858697..1859291 (-)	595	Protein_1870	methyltransferase domain-containing protein	-
L1A18_RS09550 (L1A18_09550)	comGG/cglG	1859428..1859841 (-)	414	WP_000265624.1	competence type IV pilus minor pilin ComGG	Machinery gene
L1A18_RS09555 (L1A18_09555)	comGF/cglF	1859819..1860280 (-)	462	WP_000250542.1	competence type IV pilus minor pilin ComGF	Machinery gene
L1A18_RS09560 (L1A18_09560)	comGE/cglE	1860243..1860545 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
L1A18_RS09565 (L1A18_09565)	comGD/cglD	1860508..1860912 (-)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
L1A18_RS09570 (L1A18_09570)	comGC/cglC	1860905..1861231 (-)	327	WP_000738636.1	comG operon protein ComGC	Machinery gene
L1A18_RS09575 (L1A18_09575)	comGB/cglB	1861233..1862249 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
L1A18_RS09580 (L1A18_09580)	comGA/cglA/cilD	1862197..1863138 (-)	942	WP_000249552.1	competence type IV pilus ATPase ComGA	Machinery gene
L1A18_RS09585 (L1A18_09585)	-	1863214..1863579 (-)	366	WP_000286415.1	DUF1033 family protein	-
L1A18_RS09590 (L1A18_09590)	-	1863730..1864788 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17918.53 Da
• Isoelectric Point: 9.3137

>NTDB_id=646006 L1A18_RS09555 WP_000250542.1 1859819..1860280(-) (comGF/cglF) [Streptococcus pneumoniae strain NP7536]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=646006 L1A18_RS09555 WP_000250542.1 1859819..1860280(-) (comGF/cglF) [Streptococcus pneumoniae strain NP7536]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGATCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae D39	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae R6	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae TIGR4	96.078	100	0.961
comGF/cglF	Streptococcus mitis SK321	92.157	100	0.922
comGF/cglF	Streptococcus mitis NCTC 12261	90.85	100	0.909