Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   L1A18_RS09540 Genome accession   NZ_CP090887
Coordinates   1857683..1858636 (-) Length   317 a.a.
NCBI ID   WP_000345099.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NP7536     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1852683..1863636
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A18_RS09515 (L1A18_09515) - 1853444..1854067 (-) 624 WP_000932635.1 hypothetical protein -
  L1A18_RS09520 (L1A18_09520) jag 1854118..1855104 (-) 987 WP_044811864.1 RNA-binding cell elongation regulator Jag/EloR -
  L1A18_RS09525 (L1A18_09525) - 1855123..1855947 (-) 825 WP_001809383.1 membrane protein insertase YidC -
  L1A18_RS09530 (L1A18_09530) rnpA 1855922..1856293 (-) 372 WP_000739244.1 ribonuclease P protein component -
  L1A18_RS10695 - 1856310..1856441 (-) 132 WP_000768904.1 hypothetical protein -
  L1A18_RS09535 (L1A18_09535) - 1856442..1857632 (-) 1191 WP_000167765.1 acetate kinase -
  L1A18_RS09540 (L1A18_09540) comYH 1857683..1858636 (-) 954 WP_000345099.1 class I SAM-dependent methyltransferase Machinery gene
  L1A18_RS09545 (L1A18_09545) - 1858697..1859291 (-) 595 Protein_1870 methyltransferase domain-containing protein -
  L1A18_RS09550 (L1A18_09550) comGG/cglG 1859428..1859841 (-) 414 WP_000265624.1 competence type IV pilus minor pilin ComGG Machinery gene
  L1A18_RS09555 (L1A18_09555) comGF/cglF 1859819..1860280 (-) 462 WP_000250542.1 competence type IV pilus minor pilin ComGF Machinery gene
  L1A18_RS09560 (L1A18_09560) comGE/cglE 1860243..1860545 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  L1A18_RS09565 (L1A18_09565) comGD/cglD 1860508..1860912 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  L1A18_RS09570 (L1A18_09570) comGC/cglC 1860905..1861231 (-) 327 WP_000738636.1 comG operon protein ComGC Machinery gene
  L1A18_RS09575 (L1A18_09575) comGB/cglB 1861233..1862249 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  L1A18_RS09580 (L1A18_09580) comGA/cglA/cilD 1862197..1863138 (-) 942 WP_000249552.1 competence type IV pilus ATPase ComGA Machinery gene
  L1A18_RS09585 (L1A18_09585) - 1863214..1863579 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35718.89 Da        Isoelectric Point: 4.2474

>NTDB_id=646004 L1A18_RS09540 WP_000345099.1 1857683..1858636(-) (comYH) [Streptococcus pneumoniae strain NP7536]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELEQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=646004 L1A18_RS09540 WP_000345099.1 1857683..1858636(-) (comYH) [Streptococcus pneumoniae strain NP7536]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAGACTGAGCTAGAACAGGTCAAAGACAACAATC
AGACCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTACTTTTGGTGTTTATTGTGGAAGAGCTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTTTGGGCGCTACTTTCTTGACCTCGCTTACTAAAA
AGGTGGATTATTTGGGAATGGAAGTGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAATAGCAGTGGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.952

98.738

0.543
  comYH Streptococcus mutans UA159

54.633

98.738

0.539