Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHN38_RS30975 Genome accession   NZ_CP107765
Coordinates   6729964..6730590 (-) Length   208 a.a.
NCBI ID   WP_330283921.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00588     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6724964..6735590
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHN38_RS30950 (OHN38_30925) - 6725184..6725834 (+) 651 WP_016435969.1 acetate uptake transporter family protein -
  OHN38_RS30955 (OHN38_30930) acs 6725831..6727822 (+) 1992 WP_330283917.1 acetate--CoA ligase -
  OHN38_RS30960 (OHN38_30935) - 6727876..6728352 (-) 477 WP_330283918.1 GNAT family N-acetyltransferase -
  OHN38_RS30965 (OHN38_30940) - 6728367..6728966 (-) 600 WP_330283919.1 gamma carbonic anhydrase family protein -
  OHN38_RS30970 (OHN38_30945) - 6729162..6729923 (+) 762 WP_330283920.1 nucleotidyltransferase domain-containing protein -
  OHN38_RS30975 (OHN38_30950) vraR 6729964..6730590 (-) 627 WP_330283921.1 response regulator transcription factor Regulator
  OHN38_RS30980 (OHN38_30955) - 6730587..6731789 (-) 1203 WP_330283922.1 sensor histidine kinase -
  OHN38_RS30985 (OHN38_30960) - 6731965..6732738 (+) 774 WP_016435976.1 class I SAM-dependent methyltransferase -
  OHN38_RS30990 (OHN38_30965) - 6732764..6733729 (-) 966 WP_330283923.1 endonuclease/exonuclease/phosphatase family protein -
  OHN38_RS30995 (OHN38_30970) - 6733867..6735219 (+) 1353 WP_330283924.1 amidohydrolase -
  OHN38_RS31000 (OHN38_30975) - 6735335..6735550 (+) 216 WP_242712040.1 hypothetical protein -

Sequence

Protein


Download         Length: 208 a.a.        Molecular weight: 22121.48 Da        Isoelectric Point: 6.7310

>NTDB_id=645893 OHN38_RS30975 WP_330283921.1 6729964..6730590(-) (vraR) [Streptomyces sp. NBC_00588]
MSAPVRLLLCDDHAVVRAGLRALLSSADGIEVVGEAGSGEEALAMAGRLQPDVVLMDLQLGEGMDGVTATRRLTAQGGTR
VLVLTMFDTDADITRAIEAGATGYLLKAERPDELFAAIHSAASGRTALSAPVADRLLARMRSPRPTLSDREQEILAQLAR
GLGNREIARALFISEATVKTHLGRIYAKLEVETRTGAVAVAKERRLLP

Nucleotide


Download         Length: 627 bp        

>NTDB_id=645893 OHN38_RS30975 WP_330283921.1 6729964..6730590(-) (vraR) [Streptomyces sp. NBC_00588]
GTGAGCGCGCCCGTACGTCTGCTCCTGTGCGACGACCATGCGGTGGTACGGGCCGGCCTGCGCGCCCTGCTGTCGAGCGC
CGACGGCATCGAGGTGGTCGGCGAGGCGGGCAGCGGGGAGGAGGCGCTCGCCATGGCGGGGCGCCTGCAGCCGGACGTCG
TCCTGATGGACCTGCAGCTCGGCGAGGGCATGGACGGGGTGACGGCGACCCGACGGCTGACCGCTCAAGGCGGCACGCGC
GTCCTGGTGTTGACGATGTTCGACACCGACGCCGACATCACCCGCGCCATCGAGGCGGGCGCCACGGGGTATCTGCTCAA
GGCGGAGCGCCCGGACGAGCTCTTCGCCGCGATCCACAGTGCCGCGTCGGGCCGTACGGCGCTGTCGGCCCCGGTGGCCG
ACCGTCTCCTCGCCCGGATGCGCAGCCCCCGCCCCACCCTGTCCGACCGCGAGCAGGAGATCCTCGCCCAGCTCGCCCGC
GGCCTCGGCAACCGCGAGATCGCCCGCGCCCTGTTCATCAGCGAGGCGACGGTGAAGACCCATCTCGGCCGGATCTACGC
CAAGTTGGAGGTGGAGACCCGGACGGGCGCGGTGGCGGTGGCGAAGGAGCGACGGCTGCTGCCGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(8-118)

Bacterial regulatory proteins, luxR family (GerE)

(146-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.58

99.519

0.404
  degU Bacillus subtilis subsp. subtilis str. 168

34.862

100

0.365