Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   L1A17_RS02830 Genome accession   NZ_CP090886
Coordinates   559484..560809 (+) Length   441 a.a.
NCBI ID   WP_015511364.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NP7513     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 554484..565809
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A17_RS02800 (L1A17_02800) dnaA 554822..556183 (-) 1362 WP_000660615.1 chromosomal replication initiator protein DnaA -
  L1A17_RS02805 (L1A17_02805) spo0J 556396..557154 (-) 759 WP_000410383.1 ParB/RepB/Spo0J family partition protein Regulator
  L1A17_RS02810 (L1A17_02810) htrA 557212..558393 (-) 1182 WP_000681597.1 trypsin-like peptidase domain-containing protein Regulator
  L1A17_RS02815 (L1A17_02815) rlmH 558576..559055 (+) 480 WP_000695929.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  L1A17_RS02825 (L1A17_02825) comC/comC1 559338..559463 (+) 126 WP_000799689.1 competence-stimulating peptide ComC Regulator
  L1A17_RS02830 (L1A17_02830) comD/comD1 559484..560809 (+) 1326 WP_015511364.1 competence system sensor histidine kinase ComD Regulator
  L1A17_RS02835 (L1A17_02835) comE 560806..561558 (+) 753 WP_000866065.1 competence system response regulator transcription factor ComE Regulator
  L1A17_RS02850 (L1A17_02850) - 561801..562343 (-) 543 WP_001158266.1 TetR/AcrR family transcriptional regulator -
  L1A17_RS10580 - 562522..564125 (+) 1604 Protein_563 YhgE/Pip domain-containing protein -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 51187.66 Da        Isoelectric Point: 6.9339

>NTDB_id=645895 L1A17_RS02830 WP_015511364.1 559484..560809(+) (comD/comD1) [Streptococcus pneumoniae strain NP7513]
MDLFGFGTVIVHFLIISHSYHLICKGQINRKELFVFGAYTLLTEIVFDFPLYILYLDGLGIATFLFPLGLYSYFRWIKQY
ERDRGLFLSLLLSLLYESTHNFLSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIALKQKKFEQKHLQNYTDEIVGLY
NEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEVLVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEF
TLEVKDTITKLPIELLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFALGFSTKGR
NRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=645895 L1A17_RS02830 WP_015511364.1 559484..560809(+) (comD/comD1) [Streptococcus pneumoniae strain NP7513]
ATGGATTTATTTGGATTTGGGACAGTTATTGTTCATTTTTTAATTATTAGTCACAGCTACCATTTAATTTGTAAAGGTCA
AATAAATAGAAAAGAATTATTCGTTTTTGGTGCTTATACATTACTAACAGAAATAGTATTTGATTTTCCCTTATATATTC
TATATTTAGATGGGTTAGGGATTGCAACATTTTTATTTCCTTTGGGCCTATATTCCTATTTTCGATGGATAAAACAGTAT
GAGAGGGATAGAGGACTATTCCTAAGTTTACTACTATCTCTTTTATATGAGAGCACTCATAACTTTCTGTCCGTAACTTT
CTCCTCTATAACAGGAGATAATTTTGTTTTACAATATCATTTCCCATTCTTTTTCGTTGTGACGGTGTTGACCTATTTTG
TTACATTAAAAATCATTTATTATTTCCATTTGGAACTAGCCTATTTTGACAAGGACTACCTTTATCCTTTCTTGAAAAAA
GTATTTTTTGCTTTACTATTGCTACATATTGTATCTTTCGTTTCAGATATGGTAAGTACGATTAAACATTTGAATAGTTT
TGGAAGTATTTTGTCATCTATTGTCTTTATCTCTCTCCTTTTGACCTTCTTTGCAATGAATTCTCATAAAGTTCAAATGG
AGAAAGAGATTGCTTTGAAGCAGAAGAAATTTGAACAGAAACATTTACAGAATTACACAGATGAAATTGTTGGTCTGTAT
AATGAAATCCGTGGTTTTCGACATGATTATGCTGGAATGCTTGTCAGCATGCAGATGGCAATTGACAGTGGTAATTTACA
GGAAATTGACAGAATTTACAATGAAGTTTTAGTCAAAGCAAATCATAAATTGCGTTCAGATAAGTACACTTACTTTGATT
TGAACAACATAGAAGACTCAGCTTTACGAAGTTTGGTTGCTCAGTCAATTGTCTATGCTCGAAATAATGGTGTAGAGTTT
ACACTGGAAGTAAAAGATACGATTACCAAGCTTCCAATTGAACTATTGGATTTGGTTCGTATCATGAGCGTTTTATTGAA
TAATGCTGTCGAAGGATCGGCTGATAGCTATAAAAAGCAGATGGAAGTAGCAGTTATTAAGATGGAAACTGAAACAGTTA
TTGTGATTCAGAATTCATGTAAAATGACGATGACTCCTTCAGGAGATCTATTTGCCTTAGGATTCTCCACTAAGGGAAGA
AATCGCGGAGTCGGATTAAATAATGTGAAAGAACTACTAGATAAGTACAACAATATTATTTTAGAAACAGAGATGGAAGG
CAGTACATTTAGACAAATCATTAGATTTAAGAGGGAATTTGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(334-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus pneumoniae Rx1

98.866

100

0.989
  comD/comD1 Streptococcus pneumoniae D39

98.866

100

0.989
  comD/comD1 Streptococcus pneumoniae R6

98.866

100

0.989
  comD/comD2 Streptococcus pneumoniae TIGR4

96.599

100

0.966
  comD Streptococcus mitis SK321

92.744

100

0.927
  comD Streptococcus mitis NCTC 12261

86.621

100

0.866
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

49.468

85.261

0.422
  comD/comD2 Streptococcus gordonii strain NCTC7865

49.202

85.261

0.42