Detailed information    

insolico Bioinformatically predicted

Overview


Name   comA/nlmT   Type   Regulator
Locus tag   L1A15_RS10495 Genome accession   NZ_CP090884
Coordinates   521190..521678 (-) Length   162 a.a.
NCBI ID   WP_307774349.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain MD5403     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context


Location: 516190..526678
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A15_RS02715 (L1A15_02715) - 516525..516854 (-) 330 WP_000132570.1 hypothetical protein -
  L1A15_RS02720 (L1A15_02720) - 517130..517468 (+) 339 WP_000682119.1 LytTR family DNA-binding domain-containing protein -
  L1A15_RS02725 (L1A15_02725) comE/blpR 517473..518210 (+) 738 WP_001219127.1 response regulator transcription factor Regulator
  L1A15_RS02730 (L1A15_02730) - 518224..519564 (+) 1341 WP_001017622.1 sensor histidine kinase -
  L1A15_RS02735 (L1A15_02735) blpC 519606..519761 (-) 156 WP_000358813.1 quorum-sensing system pheromone BlpC -
  L1A15_RS02740 (L1A15_02740) - 519818..521179 (-) 1362 WP_001069092.1 bacteriocin secretion accessory protein -
  L1A15_RS10495 comA/nlmT 521190..521678 (-) 489 WP_307774349.1 ATP-binding cassette domain-containing protein Regulator
  L1A15_RS10500 comA/nlmT 521662..522102 (-) 441 WP_001808911.1 ATP-binding cassette domain-containing protein Regulator
  L1A15_RS10505 comA/nlmT 522092..522817 (-) 726 WP_167750760.1 ABC transporter transmembrane domain-containing protein Regulator
  L1A15_RS10510 comA/nlmT 522762..523349 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  L1A15_RS02750 (L1A15_02750) blpI 523631..523828 (+) 198 WP_001093258.1 bacteriocin-like peptide BlpI -
  L1A15_RS02755 (L1A15_02755) cipB 524295..524444 (+) 150 WP_001808912.1 bacteriocin-like peptide BlpO Regulator
  L1A15_RS02760 (L1A15_02760) - 524548..524667 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  L1A15_RS02765 (L1A15_02765) - 525453..525836 (+) 384 WP_000877381.1 hypothetical protein -
  L1A15_RS02770 (L1A15_02770) - 525888..526577 (+) 690 WP_000760526.1 CPBP family intramembrane glutamic endopeptidase -

Sequence


Protein


Download         Length: 162 a.a.        Molecular weight: 18195.07 Da        Isoelectric Point: 7.0620

>NTDB_id=645803 L1A15_RS10495 WP_307774349.1 521190..521678(-) (comA/nlmT) [Streptococcus pneumoniae strain MD5403]
MRRHINYLPQQAYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARAL
LTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGIHQELMQAQGFYHHLF
NK

Nucleotide


Download         Length: 489 bp        

>NTDB_id=645803 L1A15_RS10495 WP_307774349.1 521190..521678(-) (comA/nlmT) [Streptococcus pneumoniae strain MD5403]
TTGCGCCGTCATATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGG
TAATCATATGATTAGTCAAGAAGATATTCTAAAAGCTTGTGAAGTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTA
TGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATCGCTCTCGCTCGTGCTCTT
TTAACTAAATCTCCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAA
TCTTATGTCCCTAACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTG
TTCTTGACCAGGGGAAAATCATTGAAGTTGGTATCCACCAAGAGTTAATGCAAGCGCAAGGTTTCTACCATCATCTATTC
AATAAATAA

Domains


Predicted by InterproScan.

(2-94)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.05

99.383

0.716

  comA Streptococcus gordonii str. Challis substr. CH1

70.37

100

0.704

  comA Streptococcus mitis NCTC 12261

68.519

100

0.685

  comA Streptococcus pneumoniae Rx1

68.519

100

0.685

  comA Streptococcus pneumoniae D39

68.519

100

0.685

  comA Streptococcus pneumoniae R6

68.519

100

0.685

  comA Streptococcus mitis SK321

67.901

100

0.679

  comA Streptococcus pneumoniae TIGR4

67.901

100

0.679

  rcrQ Streptococcus mutans UA159

40.645

95.679

0.389