Detailed information NTG0064573

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: SPB_RS09965
• Genome accession: NZ_AEUT02000001
• Coordinates: 1972400..1973608 (-)
• Length: 402 a.a.
• NCBI ID: WP_003108843.1
• Uniprot ID: A0A0E2UDP0
• Organism: Streptococcus parauberis NCFD 2020
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1967400..1978608

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPB_RS09940 (SPB_2051)	-	1967904..1968272 (-)	369	WP_003103744.1	helix-turn-helix domain-containing protein	-
SPB_RS09945 (SPB_2052)	-	1968393..1968590 (-)	198	WP_003104619.1	DUF951 domain-containing protein	-
SPB_RS09950 (SPB_2053)	dnaN	1968661..1969797 (-)	1137	WP_003103000.1	DNA polymerase III subunit beta	-
SPB_RS09955 (SPB_2054)	dnaA	1969953..1971314 (-)	1362	WP_003103926.1	chromosomal replication initiator protein DnaA	-
SPB_RS09960 (SPB_2055)	spo0J	1971551..1972324 (-)	774	WP_003102468.1	ParB/RepB/Spo0J family partition protein	Regulator
SPB_RS09965 (SPB_2056)	htrA	1972400..1973608 (-)	1209	WP_003108843.1	S1C family serine protease	Regulator
SPB_RS09970 (SPB_2057)	rlmH	1973812..1974291 (+)	480	WP_013794545.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
SPB_RS09990 (SPB_2061)	-	1974819..1977398 (-)	2580	WP_003106083.1	YfhO family protein	-

Sequence

Protein

• Length: 402 a.a.
• Molecular weight: 42581.09 Da
• Isoelectric Point: 4.9341

>NTDB_id=64573 SPB_RS09965 WP_003108843.1 1972400..1973608(-) (htrA) [Streptococcus parauberis NCFD 2020]
MSKLKSVLKVFLYLLAGFIGGVMAFFIMNSIKPTQQSDNDNVSKTTSTSKVTYNNTTSTTKAVKKVQDAVVSVINYQKID
TASSDNYNSLFGDSSESKQTDDGLAIFSEGSGVIYKKDGKDAYIVTNNHVIDGAKRIEILLADGSKIVGTLIGSDTYSDL
AVVKVSSEKIKSVAKFADSTKINIGEVAIAIGSPLGTEYANSVTEGIVSSLSRTVTLKNEEGKTVSTNAIQTDAAINPGN
SGGALINVEGQVIGINSSKISSTNEAGGAVEGMGFAIPSNDVVKIINQLEEKGEVIRPALGISMVNLGDLSTSALSQLNV
PKEVTSGIVVATVTEDMPATDKLKQYDIITAIDGEEVKTTSDLQSALYGHDINDEVKITFYRGNEKKTVTVKLTKTTKDL
EK

Nucleotide

• Length: 1209 bp

>NTDB_id=64573 SPB_RS09965 WP_003108843.1 1972400..1973608(-) (htrA) [Streptococcus parauberis NCFD 2020]
GTGTCAAAATTAAAAAGTGTTCTGAAAGTATTTCTTTATTTATTAGCTGGATTTATAGGGGGAGTAATGGCGTTCTTTAT
CATGAATTCTATTAAACCAACGCAACAATCAGATAATGATAATGTTTCAAAAACAACCAGCACAAGTAAAGTTACCTATA
ATAATACGACAAGTACTACTAAAGCAGTTAAGAAAGTTCAAGATGCAGTTGTTTCTGTTATCAACTATCAAAAGATAGAT
ACTGCTTCATCTGATAACTACAATAGTCTTTTTGGAGATAGTAGTGAATCTAAACAAACTGATGATGGTTTAGCAATTTT
CAGTGAAGGATCTGGAGTTATCTACAAAAAAGATGGTAAAGATGCTTATATCGTTACCAATAATCACGTTATTGATGGTG
CAAAACGGATTGAAATTTTACTTGCAGATGGCTCTAAAATCGTAGGTACACTCATCGGTTCAGATACTTATTCAGATTTA
GCAGTTGTAAAAGTGTCTTCAGAAAAAATCAAATCAGTTGCTAAATTTGCTGACTCAACAAAAATTAATATTGGAGAAGT
TGCCATTGCAATTGGTAGCCCTCTTGGAACAGAATATGCAAACTCAGTTACTGAGGGGATTGTTTCAAGTTTAAGTCGTA
CTGTTACCTTGAAAAATGAAGAAGGTAAAACCGTTTCAACAAATGCTATCCAAACGGACGCAGCTATTAACCCAGGTAAT
TCTGGAGGAGCACTTATTAATGTTGAAGGACAAGTAATTGGAATTAACTCAAGTAAAATTTCATCAACAAATGAAGCTGG
TGGAGCAGTTGAAGGTATGGGATTTGCAATTCCTTCTAATGATGTTGTCAAAATTATTAATCAACTTGAAGAAAAAGGTG
AAGTTATTAGACCAGCCCTTGGTATCTCAATGGTAAATCTTGGTGATCTTTCTACAAGTGCTTTATCGCAATTAAATGTA
CCTAAAGAAGTTACAAGTGGTATCGTCGTAGCAACTGTTACTGAAGATATGCCTGCTACTGATAAACTTAAACAATATGA
TATCATTACAGCTATTGACGGTGAAGAAGTTAAAACAACAAGTGATTTACAAAGTGCTCTTTACGGCCATGATATCAATG
ATGAGGTAAAAATCACCTTCTATCGTGGTAATGAAAAGAAAACTGTTACTGTTAAATTAACTAAAACAACTAAAGATTTA
GAAAAATAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (110-255)

• PDZ domain (PDZ_2) (298-393)

3D structure

• AlphaFold DB: A0A0E2UDP0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.224	97.512	0.597
htrA	Streptococcus gordonii str. Challis substr. CH1	55.416	98.756	0.547
htrA	Streptococcus mitis NCTC 12261	53.431	100	0.542
htrA	Streptococcus pneumoniae Rx1	53.448	100	0.54
htrA	Streptococcus pneumoniae D39	53.448	100	0.54
htrA	Streptococcus pneumoniae R6	53.448	100	0.54
htrA	Streptococcus pneumoniae TIGR4	53.448	100	0.54