Detailed information NTG0064554

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: SPB_RS07340
• Genome accession: NZ_AEUT02000001
• Coordinates: 1467186..1467776 (-)
• Length: 196 a.a.
• NCBI ID: WP_003104338.1
• Uniprot ID: A0A0E2U9G5
• Organism: Streptococcus parauberis NCFD 2020
• Function: degradation of ComX; require for competence development (at the early growth phase); repress competence development (at the mid-logarithmic growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1462186..1472776

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPB_RS07310 (SPB_1508)	-	1462321..1463085 (-)	765	WP_003103139.1	ABC transporter ATP-binding protein	-
SPB_RS07315 (SPB_1509)	-	1463086..1464039 (-)	954	WP_003103523.1	branched-chain amino acid ABC transporter permease	-
SPB_RS07320 (SPB_1510)	-	1464042..1464911 (-)	870	WP_003104378.1	branched-chain amino acid ABC transporter permease	-
SPB_RS07325 (SPB_1511)	-	1464950..1466125 (-)	1176	WP_003105666.1	ABC transporter substrate-binding protein	-
SPB_RS07330 (SPB_1512)	-	1466272..1466547 (-)	276	WP_003102688.1	YlbG family protein	-
SPB_RS07335 (SPB_1513)	-	1466550..1466993 (-)	444	WP_003105053.1	YlbF family regulator	-
SPB_RS07340 (SPB_1514)	clpP	1467186..1467776 (-)	591	WP_003104338.1	ATP-dependent Clp protease proteolytic subunit	Regulator
SPB_RS07345 (SPB_1515)	upp	1468171..1468800 (-)	630	WP_003104995.1	uracil phosphoribosyltransferase	-
SPB_RS07350 (SPB_1516)	-	1468968..1470605 (-)	1638	WP_003105776.1	polysaccharide biosynthesis protein	-
SPB_RS07355 (SPB_1517)	-	1470693..1472144 (+)	1452	WP_003104981.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21684.98 Da
• Isoelectric Point: 5.3086

>NTDB_id=64554 SPB_RS07340 WP_003104338.1 1467186..1467776(-) (clpP) [Streptococcus parauberis NCFD 2020]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGTKGKRFMLPNAEYLIHQPMGGAGNGTQQSDMAIVAEQLLKTRKRLEKILADNSGK
TIKVIHRDAERDYWMDAKETLAYGFIDEIMENNSLK

Nucleotide

• Length: 591 bp

>NTDB_id=64554 SPB_RS07340 WP_003104338.1 1467186..1467776(-) (clpP) [Streptococcus parauberis NCFD 2020]
ATGATTCCTGTTGTTATTGAACAAACAAGTCGTGGTGAACGATCTTATGATATTTACTCACGTTTATTAAAAGATCGTAT
TATTATGTTAACTGGTCCTGTTGAGGATAACATGGCTAATTCTATCATTGCTCAATTGTTATTCTTAGATGCACAAGATA
ATACTAAAGATATTTACCTTTATGTTAATACACCTGGTGGTTCTGTATCTGCTGGTTTAGCAATCGTTGATACAATGAAC
TTCATTAAATCTGATGTCCAAACAATTGTTATGGGGATGGCAGCTTCAATGGGTACAATTATTGCATCATCTGGAACCAA
GGGTAAACGGTTCATGTTACCAAATGCTGAGTATCTAATTCACCAACCAATGGGCGGTGCTGGAAATGGTACACAGCAGT
CGGATATGGCAATCGTTGCGGAGCAATTATTAAAAACTCGTAAACGCTTAGAAAAAATTCTTGCTGATAACAGTGGAAAA
ACAATTAAAGTAATCCATAGAGATGCTGAAAGAGATTATTGGATGGATGCTAAAGAAACTTTAGCTTATGGGTTCATCGA
TGAAATCATGGAAAACAATAGCTTGAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A0E2U9G5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus mutans UA159	93.367	100	0.934
clpP	Streptococcus pyogenes JRS4	91.327	100	0.913
clpP	Streptococcus pyogenes MGAS315	91.327	100	0.913
clpP	Lactococcus lactis subsp. cremoris KW2	90.816	100	0.908
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	90.306	100	0.903
clpP	Streptococcus thermophilus LMD-9	88.776	100	0.888
clpP	Streptococcus thermophilus LMG 18311	88.776	100	0.888
clpP	Streptococcus pneumoniae Rx1	86.667	99.49	0.862
clpP	Streptococcus pneumoniae D39	86.667	99.49	0.862
clpP	Streptococcus pneumoniae R6	86.667	99.49	0.862
clpP	Streptococcus pneumoniae TIGR4	86.667	99.49	0.862
clpP	Bacillus subtilis subsp. subtilis str. 168	56.842	96.939	0.551
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	55.44	98.469	0.546