Detailed information NTG0064537

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: SPB_RS02845
• Genome accession: NZ_AEUT02000001
• Coordinates: 573384..574223 (-)
• Length: 279 a.a.
• NCBI ID: WP_003105308.1
• Uniprot ID: F1Z061
• Organism: Streptococcus parauberis NCFD 2020
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 568384..579223

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPB_RS02830 (SPB_0580)	-	568973..570031 (-)	1059	WP_003103421.1	PTS transporter subunit IIC	-
SPB_RS02835 (SPB_0581)	-	570223..571107 (+)	885	WP_003102535.1	LysR family transcriptional regulator	-
SPB_RS02840 (SPB_0582)	topA	571143..573278 (-)	2136	WP_003105989.1	type I DNA topoisomerase	-
SPB_RS02845 (SPB_0583)	dprA	573384..574223 (-)	840	WP_003105308.1	DNA-processing protein DprA	Machinery gene
SPB_RS02850 (SPB_0584)	-	574284..574829 (-)	546	WP_003103370.1	sugar O-acetyltransferase	-
SPB_RS02855 (SPB_0585)	-	574901..575674 (-)	774	WP_003105815.1	ribonuclease HII	-
SPB_RS02860 (SPB_0586)	ylqF	575658..576512 (-)	855	WP_003105571.1	ribosome biogenesis GTPase YlqF	-
SPB_RS02865 (SPB_0587)	-	576686..577102 (-)	417	WP_003104767.1	MarR family winged helix-turn-helix transcriptional regulator	-
SPB_RS02870 (SPB_0588)	-	577124..578011 (-)	888	WP_003104209.1	lipoate--protein ligase	-

Sequence

Protein

• Length: 279 a.a.
• Molecular weight: 31114.17 Da
• Isoelectric Point: 9.3283

>NTDB_id=64537 SPB_RS02845 WP_003105308.1 573384..574223(-) (dprA) [Streptococcus parauberis NCFD 2020]
MNNFELYKLKKAGLENHRILKIIAYQEKYDKKLSLRNMALISECKQPIIFIENYKSLDIGAIKNEFNLFPSISIFDKNYP
ISLKSIYNPPVLLFYQGDISLLNQPILGVVGSRQATKKGIHAVDKIIEELNSKFVIVSGLARGIDTAAHFAAIKNGGKTI
AVIGSGMTKFYPKENHRLQKYIANNHLLISEYGPAEEPLAYHFPQRNRIIAGLSLGIIVCEARVRSGSLITCKYALDEGR
DIFAIPGTIVNNNSEGCHQLIKEGAKCVTNGLDILSEYQ

Nucleotide

• Length: 840 bp

>NTDB_id=64537 SPB_RS02845 WP_003105308.1 573384..574223(-) (dprA) [Streptococcus parauberis NCFD 2020]
ATGAATAATTTCGAACTATACAAATTGAAAAAAGCTGGACTAGAAAATCATCGCATTTTAAAAATTATCGCCTATCAGGA
AAAATATGACAAAAAACTTTCCTTACGTAATATGGCACTCATATCTGAATGCAAGCAACCAATCATTTTTATTGAGAATT
ATAAATCTTTAGACATTGGTGCAATAAAAAATGAATTCAATCTTTTTCCTTCCATTTCAATTTTTGATAAAAACTACCCA
ATTTCTTTAAAATCAATCTATAATCCACCAGTTCTTTTATTTTATCAAGGGGATATTAGCTTATTAAATCAGCCTATTTT
AGGTGTAGTGGGCTCGCGTCAGGCAACAAAAAAAGGTATTCATGCCGTTGATAAAATTATCGAAGAGTTAAATAGTAAGT
TTGTTATTGTAAGTGGATTAGCCAGAGGGATTGATACGGCTGCCCACTTTGCAGCTATCAAAAATGGAGGGAAAACAATT
GCTGTAATTGGTTCAGGGATGACTAAATTTTATCCAAAAGAAAATCATCGACTGCAAAAGTATATTGCGAATAACCATCT
ATTGATTAGTGAATATGGACCAGCAGAAGAACCTTTAGCTTATCATTTTCCTCAACGGAATCGGATAATTGCAGGGCTAT
CATTAGGAATCATAGTCTGTGAAGCCAGAGTCCGTTCTGGAAGTCTAATTACTTGTAAGTATGCACTGGATGAAGGAAGA
GATATTTTTGCAATACCAGGAACGATTGTCAATAATAATTCAGAGGGATGTCACCAGCTTATCAAAGAGGGTGCAAAATG
CGTCACAAATGGCTTAGACATCCTTTCCGAATACCAATAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (72-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-59)

3D structure

• AlphaFold DB: F1Z061

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	64.029	99.642	0.638
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	57.348	100	0.573
dprA/cilB/dalA	Streptococcus pneumoniae D39	57.348	100	0.573
dprA/cilB/dalA	Streptococcus pneumoniae R6	57.348	100	0.573
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	57.348	100	0.573
dprA/cilB/dalA	Streptococcus mitis SK321	57.348	100	0.573
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	56.631	100	0.566
dprA	Lactococcus lactis subsp. cremoris KW2	54.317	99.642	0.541
dprA	Legionella pneumophila strain ERS1305867	40.345	100	0.419
dprA	Glaesserella parasuis strain SC1401	40.84	93.907	0.384
dprA	Bacillus subtilis subsp. subtilis str. 168	40.927	92.832	0.38