Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   STRSA0001_RS01275 Genome accession   NZ_ACLO01000018
Coordinates   80499..82595 (-) Length   698 a.a.
NCBI ID   WP_002883724.1    Uniprot ID   -
Organism   Streptococcus salivarius SK126     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 75499..87595
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STRSA0001_RS01255 (STRSA0001_1785) - 76299..77201 (-) 903 WP_002883785.1 MetQ/NlpA family ABC transporter substrate-binding protein -
  STRSA0001_RS01260 (STRSA0001_1786) - 77361..78209 (-) 849 WP_002883793.1 amino acid ABC transporter substrate-binding protein -
  STRSA0001_RS01265 (STRSA0001_1787) - 78596..79990 (+) 1395 WP_227826957.1 DUF4153 domain-containing protein -
  STRSA0001_RS01270 (STRSA0001_1788) - 80042..80374 (-) 333 WP_002883800.1 DUF805 domain-containing protein -
  STRSA0001_RS01275 (STRSA0001_1789) comA 80499..82595 (-) 2097 WP_002883724.1 peptide cleavage/export ABC transporter Regulator
  - comS 82608..82682 (-) 75 - - Regulator
  STRSA0001_RS01280 (STRSA0001_1790) comR 82770..83669 (-) 900 WP_002883753.1 helix-turn-helix transcriptional regulator Regulator
  STRSA0001_RS01285 (STRSA0001_1791) - 83849..84499 (-) 651 WP_002883719.1 phosphatase PAP2 family protein -
  STRSA0001_RS01290 (STRSA0001_1792) - 84502..85059 (-) 558 WP_002883726.1 ECF transporter S component -
  STRSA0001_RS01295 (STRSA0001_1794) - 85349..85858 (-) 510 WP_002883735.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  STRSA0001_RS01300 (STRSA0001_1795) trkA 86149..87498 (+) 1350 WP_002883814.1 Trk system potassium transporter TrkA -

Sequence

Protein


Download         Length: 698 a.a.        Molecular weight: 78424.37 Da        Isoelectric Point: 8.9682

>NTDB_id=64494 STRSA0001_RS01275 WP_002883724.1 80499..82595(-) (comA) [Streptococcus salivarius SK126]
MSKYPYISQVDQRDCGVAALAMILKHYGSSYSLAYLRELAQTSREGTSALGLVEAAKQLGLETQAIRADLDLFKQESLSY
PFIAHVVKEGGLQHYYTVFGQIKGKLVIGDPDPSKKVIKMPLEEFAKEWTGVALFFVPGETYTKYKEDVPGLLSFLPILF
RRKGLIAVIVLLSFLVTLVNIIGSYYLQSIIDRLIPQEAYTLLTMISLGLCISYLAQQVFTFFKDYLLHRLGNYLSIAVI
LPYIKHVLSLPISFFSSRRTGEITSRFGDANTIIDALASTILSIFLDVTIVMTLAVALILQNQSLFVMTLTVVPLYVLII
LAFYKLFEKENYQLMEANSQVNTAVIDDLRGIETLKSLRVEERRYQEIEVKFHDYLKKSLSKAKWQLTQDGLKTGVQLVS
NVFILWYGAQLAMEGQLSAGQLITYNMLLNYFTTPLINIINLQSKIQQAKVANNRLQEVYVVDKEEKGKLKELSFKQLAL
KGVSHRFSYQQETLSKIDLTIHKGEKIALMGKSGSGKTTLAKMLSGYYTKSSGHVTLDKDAIGHAELRQMVTYVPQQTYV
FTGTILENLLLGFEGEVDEKELLKVCQQVDILEDIQKMPLGFQTQVSEDGGLSGGQKQRLAIARALLSKQPILIFDEATS
GLDSDTESRVMANLAKIKRTMIFIAHRNSVRQHVSRVVTMVSGQIESDSPNFNPFQFI

Nucleotide


Download         Length: 2097 bp        

>NTDB_id=64494 STRSA0001_RS01275 WP_002883724.1 80499..82595(-) (comA) [Streptococcus salivarius SK126]
ATGTCAAAATATCCATATATTTCACAGGTTGATCAGCGTGATTGTGGTGTAGCTGCCTTAGCCATGATTCTTAAACACTA
TGGTTCATCTTATAGTTTAGCTTATTTGCGGGAGTTGGCTCAGACTTCTCGTGAAGGCACTTCTGCGCTTGGTTTGGTTG
AAGCGGCCAAGCAGTTGGGCCTTGAAACTCAGGCTATTCGTGCGGATTTAGACTTGTTTAAACAAGAAAGCCTATCTTAT
CCTTTTATTGCACATGTGGTTAAAGAAGGTGGATTGCAACATTATTATACGGTGTTTGGTCAAATCAAGGGGAAGCTTGT
TATTGGTGATCCAGATCCTAGCAAGAAGGTCATTAAAATGCCCTTAGAGGAGTTTGCCAAAGAGTGGACGGGAGTTGCTC
TCTTTTTTGTTCCAGGAGAAACCTACACTAAATACAAAGAAGATGTGCCTGGGCTTCTTTCATTTTTACCAATTTTGTTT
CGTCGTAAGGGATTGATTGCAGTCATTGTCTTACTGAGTTTTCTAGTGACCCTTGTTAATATTATTGGTTCTTATTATTT
GCAATCTATTATTGACCGCTTGATTCCTCAGGAGGCCTACACTCTTCTGACAATGATTTCGCTAGGCCTATGTATCTCTT
ATCTAGCTCAACAAGTATTTACTTTTTTCAAAGATTATCTTCTACATCGATTGGGGAATTACTTGTCCATTGCTGTCATT
CTTCCTTATATTAAGCATGTCCTTTCCCTACCGATTAGTTTCTTTAGTTCACGTCGTACTGGTGAAATCACATCACGTTT
TGGAGATGCCAACACTATTATCGATGCTCTAGCTTCAACGATTTTATCAATTTTCCTAGATGTGACCATTGTGATGACTC
TAGCTGTGGCCCTTATTTTACAAAATCAGTCACTTTTTGTGATGACACTCACGGTAGTTCCTCTTTATGTGTTAATCATT
TTGGCATTCTATAAGCTTTTTGAAAAGGAAAATTATCAATTGATGGAGGCAAATAGTCAGGTCAATACCGCTGTTATTGA
TGATTTGCGAGGCATTGAAACCTTAAAATCCTTGAGAGTTGAAGAGAGACGGTATCAGGAAATTGAGGTGAAATTCCATG
ACTATTTGAAGAAGTCTTTGTCTAAGGCTAAGTGGCAATTAACGCAGGATGGTTTAAAGACGGGGGTTCAGTTAGTTTCC
AATGTCTTTATCCTCTGGTATGGGGCACAATTGGCCATGGAAGGACAGCTATCTGCAGGTCAGTTGATTACCTATAATAT
GTTGCTGAATTATTTTACAACTCCTTTAATTAATATTATCAATCTCCAATCAAAAATTCAGCAAGCCAAAGTAGCCAATA
ATCGTCTTCAAGAAGTTTATGTTGTGGACAAGGAAGAAAAAGGAAAACTTAAAGAGTTATCCTTTAAACAACTTGCTCTT
AAGGGTGTCAGTCACCGTTTTAGTTATCAGCAAGAGACGCTTAGTAAGATTGATTTAACGATTCATAAGGGTGAGAAAAT
TGCCCTCATGGGTAAAAGTGGATCTGGGAAAACGACCTTAGCGAAAATGTTGTCGGGTTATTACACAAAATCTAGTGGTC
ATGTAACCCTAGATAAAGATGCTATTGGCCATGCGGAGCTGCGTCAAATGGTGACTTACGTTCCCCAGCAGACCTATGTG
TTTACTGGAACCATTTTAGAAAATCTGCTGTTAGGATTTGAAGGAGAAGTTGACGAGAAAGAGCTTCTTAAGGTTTGCCA
ACAAGTTGATATCTTAGAGGATATTCAAAAAATGCCACTAGGTTTTCAGACCCAAGTATCTGAGGATGGTGGTCTATCTG
GTGGTCAAAAACAACGCTTGGCGATAGCGAGGGCCCTCTTGTCGAAGCAGCCTATCTTGATTTTTGACGAAGCTACCAGT
GGTCTCGATAGTGATACTGAAAGCAGGGTTATGGCTAATCTTGCTAAGATTAAACGAACAATGATTTTTATTGCTCACCG
CAATAGTGTCCGTCAACATGTCAGTCGTGTGGTGACCATGGTGAGTGGCCAGATTGAGTCGGACAGTCCTAATTTCAATC
CATTCCAGTTTATTTAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(3-139)

ABC transporter transmembrane region (ABC_membrane)

(167-436)

ABC transporter (ABC_tran)

(494-640)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

53.69

98.997

0.532
  comA Streptococcus gordonii str. Challis substr. CH1

53.017

99.713

0.529
  comA Streptococcus mitis NCTC 12261

53.256

98.997

0.527
  comA Streptococcus pneumoniae Rx1

53.111

98.997

0.526
  comA Streptococcus pneumoniae D39

53.111

98.997

0.526
  comA Streptococcus pneumoniae R6

53.111

98.997

0.526
  comA Streptococcus pneumoniae TIGR4

52.967

98.997

0.524
  comA/nlmT Streptococcus mutans UA159

50

98.854

0.494

Multiple sequence alignment