Detailed information NTG0640725

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: LXE94_RS18030
• Genome accession: NZ_CP090125
• Coordinates: 3371987..3372580 (+)
• Length: 197 a.a.
• NCBI ID: WP_003228214.1
• Uniprot ID: A0A199WEF2
• Organism: Bacillus subtilis strain Bs96
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3366987..3377580

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LXE94_RS18000 (LXE94_17955)	-	3368059..3368643 (+)	585	WP_003228226.1	TetR family transcriptional regulator	-
LXE94_RS18005 (LXE94_17960)	psmA	3368725..3369060 (+)	336	WP_014480966.1	SMR family transporter	-
LXE94_RS18010 (LXE94_17965)	psmB	3369060..3369380 (+)	321	WP_014480967.1	QacE family quaternary ammonium compound efflux SMR transporter	-
LXE94_RS18015 (LXE94_17970)	yvdQ	3369416..3369924 (-)	509	Protein_3488	DUF3231 family protein	-
LXE94_RS21595	-	3370072..3370206 (-)	135	Protein_3489	poly-gamma-glutamate hydrolase family protein	-
LXE94_RS18020 (LXE94_17975)	cotR	3370396..3371358 (+)	963	WP_042975291.1	sporulation hydrolase CotR	-
LXE94_RS18030 (LXE94_17985)	clpP	3371987..3372580 (+)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
LXE94_RS18035 (LXE94_17990)	pgmB	3372643..3373317 (-)	675	WP_257986226.1	beta-phosphoglucomutase	-
LXE94_RS18040 (LXE94_17995)	malL	3373314..3374999 (-)	1686	WP_080529825.1	oligo-1,6-glucosidase	-
LXE94_RS18045 (LXE94_18000)	mdxK	3374992..3377265 (-)	2274	WP_257986709.1	maltose phosphorylase	-

Sequence

Protein

• Length: 197 a.a.
• Molecular weight: 21682.00 Da
• Isoelectric Point: 4.9416

>NTDB_id=640725 LXE94_RS18030 WP_003228214.1 3371987..3372580(+) (clpP) [Bacillus subtilis strain Bs96]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

• Length: 594 bp

>NTDB_id=640725 LXE94_RS18030 WP_003228214.1 3371987..3372580(+) (clpP) [Bacillus subtilis strain Bs96]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGCATGGCTGCGTCAATGGGCGCGTTCCTGCTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCACTTGGCGGTGCGCAAGGTCAGGCGA
CAGAAATTGAAATTGCCGCGAAACGCATTCTCTTGCTTCGCGACAAACTAAACAAAGTCCTTGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A199WEF2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538