Detailed information NTG0640119

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: LV497_RS04275
• Genome accession: NZ_CP090007
• Coordinates: 988729..989829 (-)
• Length: 366 a.a.
• NCBI ID: WP_156024868.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain SALI-10
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 983729..994829

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LV497_RS04235 (LV497_04235)	-	984338..984535 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
LV497_RS04240 (LV497_04240)	-	984786..985979 (-)	1194	WP_002885831.1	acetate kinase	-
LV497_RS04245 (LV497_04245)	comYH	986036..986992 (-)	957	WP_022496101.1	class I SAM-dependent methyltransferase	Machinery gene
LV497_RS04250 (LV497_04250)	comGG	987037..987354 (-)	318	WP_021144683.1	competence type IV pilus minor pilin ComGG	-
LV497_RS04255 (LV497_04255)	comYF	987332..987769 (-)	438	WP_022496100.1	competence type IV pilus minor pilin ComGF	Machinery gene
LV497_RS04260 (LV497_04260)	comGE	987756..987986 (-)	231	WP_002887015.1	competence type IV pilus minor pilin ComGE	-
LV497_RS04265 (LV497_04265)	comYD	988018..988446 (-)	429	WP_014632541.1	competence type IV pilus minor pilin ComGD	Machinery gene
LV497_RS04270 (LV497_04270)	comYC	988406..988720 (-)	315	WP_037611125.1	competence type IV pilus major pilin ComGC	Machinery gene
LV497_RS04275 (LV497_04275)	comYB	988729..989829 (-)	1101	WP_156024868.1	competence type IV pilus assembly protein ComGB	Machinery gene
LV497_RS04280 (LV497_04280)	comYA	989711..990652 (-)	942	WP_022496097.1	competence type IV pilus ATPase ComGA	Machinery gene
LV497_RS04285 (LV497_04285)	-	990732..991094 (-)	363	WP_245085384.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41666.79 Da
• Isoelectric Point: 10.1478

>NTDB_id=640119 LV497_RS04275 WP_156024868.1 988729..989829(-) (comYB) [Streptococcus salivarius strain SALI-10]
MPVKISKAIRQPTGTSSWKAWLNKDISLKGISKGKKLKINQQLKVIQLFKQLLKAGFTLTEIVAFLERSHLLKESSLSLM
KASLMRGDRLDQMFASVGFSDNIVTQIALADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKENWAVQLVQIFPQLFFVTLCGLLVLSLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGIDLLDLVALMKEQKSKLFRELGADLEEALMLGQSFPDRIATHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QAFFNRLNKATTFVQPLIFVIVAVVIVMIYAAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=640119 LV497_RS04275 WP_156024868.1 988729..989829(-) (comYB) [Streptococcus salivarius strain SALI-10]
TTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAACTGGAACCAGCAGTTGGAAGGCTTGGTTAAACAAGGATATCTC
ACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAATCAGCAACTCAAGGTTATCCAGCTTTTCAAACAACTTTTAA
AGGCAGGGTTTACCTTGACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGTTGAAAGAATCGTCCTTGTCTCTTATG
AAAGCGAGCTTAATGCGAGGCGACAGGTTGGACCAGATGTTTGCGTCAGTAGGTTTTTCGGACAATATTGTTACTCAGAT
TGCCCTTGCTGATAAGCACGGTAATCTTCTAGGGAGTTTAACCAAGATTGAAACCTACATGCTTCGTATGACCAAGGTTC
GTAAGAAACTCATGGAGGTAGCGACCTATCCTATTCTACTTCTGGGTTTCCTGATTCTGATTATGTTGGGGCTCAAAAAT
TATCTTCTGCCTCAACTGTTAGAGGGGGATGGTAAGGAGAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTCTT
TTTTGTGACTTTGTGCGGACTTCTTGTATTAAGCTTAATTCTCTATCTATGGGTGAAACGCCAGTCAGCCCTTGTCTTTT
ATCGACGAATGGCAAAAATCCCTTTTATAGGCCAAACTGTCAGGCTATATACGACTGCCTATTATGCTAGAGAATGGGGA
AATCTCTTAGGGCAAGGTATTGACTTGCTAGACTTAGTTGCTCTAATGAAAGAGCAAAAGTCCAAGCTTTTTCGTGAGCT
GGGGGCTGATTTAGAGGAAGCCTTGATGCTAGGACAGAGTTTTCCTGACCGAATTGCTACTCACCCATTTTTCACTAAGG
AGCTATCCTTAATTATTGCTTATGGAGAGGCCAATGCTAGGTTGGGCTATGAGTTAGAAGTCTATGCTGAAGAGGTTTGG
CAGGCTTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCTGTCGTGATTGT
AATGATCTATGCAGCTATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	55.394	93.716	0.519
comYB	Streptococcus mutans UA159	55.394	93.716	0.519
comYB	Streptococcus gordonii str. Challis substr. CH1	51.312	93.716	0.481
comGB/cglB	Streptococcus mitis NCTC 12261	50.737	92.623	0.47
comGB/cglB	Streptococcus mitis SK321	50	92.35	0.462
comGB/cglB	Streptococcus pneumoniae Rx1	49.704	92.35	0.459
comGB/cglB	Streptococcus pneumoniae D39	49.704	92.35	0.459
comGB/cglB	Streptococcus pneumoniae R6	49.704	92.35	0.459
comGB/cglB	Streptococcus pneumoniae TIGR4	49.704	92.35	0.459
comGB	Lactococcus lactis subsp. cremoris KW2	44.985	89.891	0.404