Detailed information
Bioinformatically predicted
Overview
| Name | clpP | Type | Regulator |
| Locus tag | LXA49_RS03735 | Genome accession | NZ_CP089949 |
| Coordinates | 727118..727708 (+) | Length | 196 a.a. |
| NCBI ID | WP_000613477.1 | Uniprot ID | A0A064BX72 |
| Organism | Streptococcus pneumoniae strain SN75752 | ||
| Function | degradation of ComX; degradation of ComW (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 725759..736769 | 727118..727708 | within | 0 |
Gene organization within MGE regions
Location: 725759..736769
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LXA49_RS03725 (LXA49_03720) | - | 725759..726226 (+) | 468 | WP_000136976.1 | cytidine/deoxycytidylate deaminase family protein | - |
| LXA49_RS03730 (LXA49_03725) | upp | 726315..726944 (+) | 630 | WP_000515974.1 | uracil phosphoribosyltransferase | - |
| LXA49_RS03735 (LXA49_03730) | clpP | 727118..727708 (+) | 591 | WP_000613477.1 | ATP-dependent Clp protease proteolytic subunit ClpP | Regulator |
| LXA49_RS03740 (LXA49_03735) | - | 727787..728035 (+) | 249 | WP_000462126.1 | YlbG family protein | - |
| LXA49_RS03745 (LXA49_03740) | - | 728136..729296 (+) | 1161 | WP_000726146.1 | ABC transporter substrate-binding protein | - |
| LXA49_RS03750 (LXA49_03745) | - | 729564..730433 (+) | 870 | WP_000941421.1 | branched-chain amino acid ABC transporter permease | - |
| LXA49_RS03755 (LXA49_03750) | - | 730437..731393 (+) | 957 | WP_000662293.1 | branched-chain amino acid ABC transporter permease | - |
| LXA49_RS03760 (LXA49_03755) | - | 731393..732157 (+) | 765 | WP_001186003.1 | ABC transporter ATP-binding protein | - |
| LXA49_RS03765 (LXA49_03760) | - | 732157..732867 (+) | 711 | WP_000062220.1 | ABC transporter ATP-binding protein | - |
| LXA49_RS03770 (LXA49_03765) | - | 733281..733937 (+) | 657 | WP_000268654.1 | CBS domain-containing protein | - |
| LXA49_RS03775 (LXA49_03770) | prfB | 734045..735140 (+) | 1096 | WP_099975370.1 | peptide chain release factor 2 | - |
| LXA49_RS03780 (LXA49_03775) | ftsE | 735158..735850 (+) | 693 | WP_000022268.1 | cell division ATP-binding protein FtsE | - |
| LXA49_RS03785 (LXA49_03780) | ftsX | 735843..736769 (+) | 927 | WP_000625536.1 | permease-like cell division protein FtsX | - |
Sequence
Protein
Download Length: 196 a.a. Molecular weight: 21358.36 Da Isoelectric Point: 4.4910
>NTDB_id=639401 LXA49_RS03735 WP_000613477.1 727118..727708(+) (clpP) [Streptococcus pneumoniae strain SN75752]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
Nucleotide
Download Length: 591 bp
>NTDB_id=639401 LXA49_RS03735 WP_000613477.1 727118..727708(+) (clpP) [Streptococcus pneumoniae strain SN75752]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACAGGTCCGGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGATA
GTACGAAAGATATTTACCTTTATGTCAATACACCAGGTGGTTCTGTTTCAGCTGGTTTGGCAATCGTAGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACCATTGTTATGGGAATGGCTGCATCTATGGGGACTGTCATCGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATACATGATTCACCAACCAATGGGCGGTACAGGTGGTGGTACCCAACAAA
CTGATATGGCTATCGCTGCAGAACACTTGCTCAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATGGAAAAAGTCCATGCAGATGCAGAACGTGATAACTGGATGAGCGCCCAGGAAACACTTGAATATGGCTTTATTGA
TGAAATTATGGCCAACAATTCATTGAACTAA
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACAGGTCCGGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGATA
GTACGAAAGATATTTACCTTTATGTCAATACACCAGGTGGTTCTGTTTCAGCTGGTTTGGCAATCGTAGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACCATTGTTATGGGAATGGCTGCATCTATGGGGACTGTCATCGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATACATGATTCACCAACCAATGGGCGGTACAGGTGGTGGTACCCAACAAA
CTGATATGGCTATCGCTGCAGAACACTTGCTCAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATGGAAAAAGTCCATGCAGATGCAGAACGTGATAACTGGATGAGCGCCCAGGAAACACTTGAATATGGCTTTATTGA
TGAAATTATGGCCAACAATTCATTGAACTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpP | Streptococcus pneumoniae Rx1 |
100 |
100 |
1 |
| clpP | Streptococcus pneumoniae D39 |
100 |
100 |
1 |
| clpP | Streptococcus pneumoniae R6 |
100 |
100 |
1 |
| clpP | Streptococcus pneumoniae TIGR4 |
100 |
100 |
1 |
| clpP | Streptococcus thermophilus LMG 18311 |
92.821 |
99.49 |
0.923 |
| clpP | Streptococcus thermophilus LMD-9 |
92.821 |
99.49 |
0.923 |
| clpP | Streptococcus pyogenes JRS4 |
90.769 |
99.49 |
0.903 |
| clpP | Streptococcus pyogenes MGAS315 |
90.769 |
99.49 |
0.903 |
| clpP | Streptococcus mutans UA159 |
85.714 |
100 |
0.857 |
| clpP | Lactococcus lactis subsp. lactis strain DGCC12653 |
85.128 |
99.49 |
0.847 |
| clpP | Lactococcus lactis subsp. cremoris KW2 |
84.615 |
99.49 |
0.842 |
| clpP | Bacillus subtilis subsp. subtilis str. 168 |
58.854 |
97.959 |
0.577 |
| clpP | Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 |
58.031 |
98.469 |
0.571 |