Detailed information NTG0638443

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: LU294_RS13220
• Genome accession: NZ_CP089743
• Coordinates: 2543088..2543669 (+)
• Length: 193 a.a.
• NCBI ID: WP_000991625.1
• Uniprot ID: A0A2A8KY00
• Organism: Bacillus paranthracis strain SHOU-BC01
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2538088..2548669

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LU294_RS13195 (LU294_13195)	-	2539209..2540576 (+)	1368	WP_000795733.1	lytic polysaccharide monooxygenase	-
LU294_RS13200 (LU294_13200)	-	2540707..2541141 (-)	435	WP_000555715.1	GNAT family N-acetyltransferase	-
LU294_RS13205 (LU294_13205)	rpiA	2541249..2541911 (-)	663	WP_073541730.1	ribose 5-phosphate isomerase A	-
LU294_RS13210 (LU294_13210)	-	2541916..2542236 (-)	321	WP_001125380.1	2Fe-2S iron-sulfur cluster-binding protein	-
LU294_RS13215 (LU294_13215)	-	2542380..2543066 (+)	687	WP_000337494.1	RNA polymerase subunit sigma-70	-
LU294_RS13220 (LU294_13220)	clpP	2543088..2543669 (+)	582	WP_000991625.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
LU294_RS13225 (LU294_13225)	-	2543715..2544572 (-)	858	WP_001227647.1	glycine betaine ABC transporter substrate-binding protein	-
LU294_RS13230 (LU294_13230)	-	2544743..2545948 (+)	1206	WP_000370624.1	quaternary amine ABC transporter ATP-binding protein	-
LU294_RS13235 (LU294_13235)	-	2545941..2546777 (+)	837	WP_001084764.1	ABC transporter permease	-
LU294_RS13240 (LU294_13240)	-	2547074..2547244 (+)	171	WP_232685456.1	septum formation initiator	-
LU294_RS13245 (LU294_13245)	-	2547347..2547832 (+)	486	WP_002163623.1	HIT family protein	-
LU294_RS13250 (LU294_13250)	-	2547816..2548652 (+)	837	WP_000557569.1	PP2C family serine/threonine-protein phosphatase	-

Sequence

Protein

• Length: 193 a.a.
• Molecular weight: 21178.42 Da
• Isoelectric Point: 5.0776

>NTDB_id=638443 LU294_RS13220 WP_000991625.1 2543088..2543669(+) (clpP) [Bacillus paranthracis strain SHOU-BC01]
MNAIPYVVEQTKLGERSYDIYSRLLKDRIVIIGSEINDQVASSVVAQLLFLEAEDAEKDIFLYINSPGGSTTAGFAILDT
MNLIKPDVQTLCMGFAASFGALLLLSGAKGKRFALPNSEIMIHQPLGGAQGQATEIEITAKRILKLKHDINKMIAEKTGQ
PIERVAHDTERDYFMTAEEAKAYGIVDDVVTKK

Nucleotide

• Length: 582 bp

>NTDB_id=638443 LU294_RS13220 WP_000991625.1 2543088..2543669(+) (clpP) [Bacillus paranthracis strain SHOU-BC01]
ATGAATGCAATTCCATATGTTGTAGAGCAAACGAAATTAGGAGAACGTTCCTATGATATATACTCAAGGTTATTAAAAGA
CCGTATTGTTATTATCGGTTCAGAAATAAATGATCAAGTAGCGAGTAGTGTCGTAGCTCAATTATTATTTTTAGAAGCAG
AAGATGCAGAGAAAGATATATTTTTATACATTAATAGCCCAGGCGGATCAACGACAGCAGGTTTTGCCATATTGGATACG
ATGAATTTAATCAAACCAGACGTGCAAACGCTATGCATGGGCTTTGCAGCATCATTTGGTGCATTGCTATTATTATCAGG
TGCAAAAGGAAAACGGTTTGCACTCCCAAATAGTGAAATTATGATTCATCAGCCGCTTGGTGGTGCACAAGGGCAAGCAA
CGGAAATTGAAATCACAGCAAAAAGAATTTTAAAGTTAAAACATGATATTAATAAAATGATTGCAGAAAAAACAGGGCAA
CCGATTGAAAGAGTAGCACATGATACAGAAAGAGATTATTTTATGACTGCAGAAGAAGCGAAGGCATATGGGATTGTAGA
TGATGTTGTTACGAAAAAATAG

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (14-192)

3D structure

• AlphaFold DB: A0A2A8KY00

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	68.063	98.964	0.674
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	66.667	97.927	0.653
clpP	Streptococcus thermophilus LMD-9	54.688	99.482	0.544
clpP	Streptococcus pneumoniae Rx1	54.688	99.482	0.544
clpP	Streptococcus thermophilus LMG 18311	54.688	99.482	0.544
clpP	Streptococcus pneumoniae D39	54.688	99.482	0.544
clpP	Streptococcus pneumoniae R6	54.688	99.482	0.544
clpP	Streptococcus pneumoniae TIGR4	54.688	99.482	0.544
clpP	Streptococcus pyogenes MGAS315	55.556	97.927	0.544
clpP	Streptococcus pyogenes JRS4	55.556	97.927	0.544
clpP	Streptococcus mutans UA159	53.439	97.927	0.523
clpP	Lactococcus lactis subsp. cremoris KW2	51.852	97.927	0.508
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	49.735	97.927	0.487