Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   LUS72_RS25475 Genome accession   NZ_CP089518
Coordinates   4860432..4861013 (+) Length   193 a.a.
NCBI ID   WP_001049163.1    Uniprot ID   A0A366GQ86
Organism   Bacillus cereus strain PT1     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 4855432..4866013
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUS72_RS25435 - 4855855..4856208 (-) 354 WP_264448407.1 YxeA family protein -
  LUS72_RS25440 - 4856414..4856620 (+) 207 WP_000216167.1 DUF1657 domain-containing protein -
  LUS72_RS25445 - 4856728..4857216 (+) 489 WP_097832339.1 YhcN/YlaJ family sporulation lipoprotein -
  LUS72_RS25450 spoVAC 4857245..4857721 (+) 477 WP_002034730.1 stage V sporulation protein AC -
  LUS72_RS25455 spoVAD 4857722..4858738 (+) 1017 WP_097832341.1 stage V sporulation protein AD -
  LUS72_RS25460 spoVAE 4858735..4859085 (+) 351 WP_000575919.1 stage V sporulation protein AE -
  LUS72_RS25465 - 4859097..4859303 (+) 207 WP_016125685.1 DUF1657 domain-containing protein -
  LUS72_RS25470 - 4859323..4860192 (+) 870 WP_097832342.1 DUF421 domain-containing protein -
  LUS72_RS25475 clpP 4860432..4861013 (+) 582 WP_001049163.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  LUS72_RS25480 - 4861555..4861803 (-) 249 WP_000250255.1 HPr family phosphocarrier protein -
  LUS72_RS25485 whiA 4861827..4862777 (-) 951 WP_000006563.1 DNA-binding protein WhiA -
  LUS72_RS25490 - 4862866..4863819 (-) 954 WP_097832343.1 gluconeogenesis factor YvcK family protein -
  LUS72_RS25495 rapZ 4863823..4864704 (-) 882 WP_000138460.1 RNase adapter RapZ -
  LUS72_RS25500 - 4864725..4865183 (-) 459 WP_001190080.1 NUDIX hydrolase -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21447.68 Da        Isoelectric Point: 5.0423

>NTDB_id=637902 LUS72_RS25475 WP_001049163.1 4860432..4861013(+) (clpP) [Bacillus cereus strain PT1]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLESQDPEKDIHIYINSPGGSITAGMAIYDT
MQFIKPQVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILFLREKLNQILADRTGQ
PLEVLQRDTDRDNFMTAERALEYGLIDKIFTNR

Nucleotide


Download         Length: 582 bp        

>NTDB_id=637902 LUS72_RS25475 WP_001049163.1 4860432..4861013(+) (clpP) [Bacillus cereus strain PT1]
ATGAATTTAATTCCTACAGTAATTGAACAAACAAATCGTGGAGAACGCGCTTACGATATTTACTCTCGACTATTAAAAGA
CCGCATCATTATGCTTGGTAGCGCAATTGATGACAACGTAGCAAACTCAATCGTTTCCCAGCTTTTATTCTTGGAATCTC
AAGATCCAGAAAAAGATATTCACATCTACATCAACAGCCCTGGTGGTTCTATCACAGCAGGTATGGCAATTTACGATACA
ATGCAGTTTATTAAACCACAAGTATCAACAATCTGTATCGGTATGGCTGCATCTATGGGTGCATTCTTACTTGCAGCAGG
TGAAAAAGGAAAACGTTATGCACTTCCAAACAGTGAAGTAATGATTCACCAACCACTTGGTGGTGCACAAGGTCAAGCGA
CTGAAATCGAAATCGCTGCAAAACGCATCCTATTCTTACGTGAAAAATTAAACCAAATTCTTGCTGACCGTACAGGTCAA
CCACTTGAAGTTCTACAACGCGACACAGACCGCGACAACTTCATGACAGCAGAAAGAGCTCTAGAATACGGCTTAATCGA
TAAGATCTTTACAAATCGTTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A366GQ86

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

90.104

99.482

0.896
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

67.021

97.409

0.653
  clpP Streptococcus thermophilus LMG 18311

60.417

99.482

0.601
  clpP Streptococcus thermophilus LMD-9

60.417

99.482

0.601
  clpP Lactococcus lactis subsp. cremoris KW2

58.854

99.482

0.585
  clpP Streptococcus pneumoniae D39

57.292

99.482

0.57
  clpP Streptococcus pneumoniae Rx1

57.292

99.482

0.57
  clpP Streptococcus pneumoniae R6

57.292

99.482

0.57
  clpP Streptococcus pneumoniae TIGR4

57.292

99.482

0.57
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

56.771

99.482

0.565
  clpP Streptococcus pyogenes JRS4

55.729

99.482

0.554
  clpP Streptococcus pyogenes MGAS315

55.729

99.482

0.554
  clpP Streptococcus mutans UA159

55.44

100

0.554