Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   LUY92_RS02180 Genome accession   NZ_CP089473
Coordinates   401486..402172 (+) Length   228 a.a.
NCBI ID   WP_001802022.1    Uniprot ID   A0A7U7EYP5
Organism   Staphylococcus aureus strain 0.1239_III_ST239     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 396486..407172
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUY92_RS02145 yqeH 397013..398113 (+) 1101 WP_001280137.1 ribosome biogenesis GTPase YqeH -
  LUY92_RS02150 aroE 398127..398933 (+) 807 WP_000666757.1 shikimate dehydrogenase -
  LUY92_RS02155 yhbY 398937..399227 (+) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  LUY92_RS02160 nadD 399230..399799 (+) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  LUY92_RS02165 yqeK 399789..400373 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  LUY92_RS02170 rsfS 400374..400727 (+) 354 WP_001088020.1 ribosome silencing factor -
  LUY92_RS02175 - 400730..401446 (+) 717 WP_000084830.1 class I SAM-dependent methyltransferase -
  LUY92_RS02180 comEA 401486..402172 (+) 687 WP_001802022.1 ComEA family DNA-binding protein Machinery gene
  LUY92_RS02185 - 402264..402725 (+) 462 WP_000439693.1 ComE operon protein 2 -
  LUY92_RS02190 comEC 402730..404931 (+) 2202 WP_001557362.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  LUY92_RS02195 holA 404988..405962 (+) 975 WP_001282563.1 DNA polymerase III subunit delta -
  LUY92_RS02200 rpsT 406007..406258 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25900.65 Da        Isoelectric Point: 9.6751

>NTDB_id=637025 LUY92_RS02180 WP_001802022.1 401486..402172(+) (comEA) [Staphylococcus aureus strain 0.1239_III_ST239]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=637025 LUY92_RS02180 WP_001802022.1 401486..402172(+) (comEA) [Staphylococcus aureus strain 0.1239_III_ST239]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAGTGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAATAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCGAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EYP5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus N315

100

100

1
  comEA Staphylococcus aureus MW2

97.368

100

0.974