Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   YBT1518_RS28345 Genome accession   NC_022873
Coordinates   5600956..5601537 (+) Length   193 a.a.
NCBI ID   WP_001049162.1    Uniprot ID   A0A9W5QPC2
Organism   Bacillus thuringiensis YBT-1518     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 5566279..5601537 5600956..5601537 within 0


Gene organization within MGE regions


Location: 5566279..5601537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  YBT1518_RS28130 (YBT1518_28605) - 5566279..5566524 (-) 246 WP_000869730.1 glutaredoxin family protein -
  YBT1518_RS28135 (YBT1518_28610) rpoN 5566534..5567841 (-) 1308 WP_000647953.1 RNA polymerase factor sigma-54 -
  YBT1518_RS28140 (YBT1518_28615) - 5568143..5568340 (-) 198 WP_000505575.1 hypothetical protein -
  YBT1518_RS28145 (YBT1518_28620) - 5568360..5569388 (-) 1029 WP_023523426.1 ABC transporter permease -
  YBT1518_RS28150 (YBT1518_28625) - 5569585..5570469 (-) 885 WP_023523427.1 ABC transporter ATP-binding protein -
  YBT1518_RS28155 (YBT1518_28630) - 5570786..5573104 (+) 2319 WP_023523428.1 sensor histidine kinase -
  YBT1518_RS28160 (YBT1518_28635) - 5573108..5573749 (+) 642 WP_023523429.1 response regulator transcription factor -
  YBT1518_RS28165 (YBT1518_28640) - 5574148..5574972 (+) 825 WP_023523430.1 helix-turn-helix domain-containing protein -
  YBT1518_RS28170 (YBT1518_28645) - 5574989..5575282 (-) 294 WP_023523431.1 YolD-like family protein -
  YBT1518_RS38830 (YBT1518_28650) - 5575649..5577034 (-) 1386 WP_023523432.1 beta-propeller fold lactonase family protein -
  YBT1518_RS37210 - 5577282..5577452 (+) 171 WP_157762869.1 hypothetical protein -
  YBT1518_RS39005 - 5577482..5577712 (+) 231 WP_370451655.1 hypothetical protein -
  YBT1518_RS28185 (YBT1518_28655) - 5579399..5580460 (-) 1062 WP_023523433.1 N-acetylmuramoyl-L-alanine amidase -
  YBT1518_RS28190 (YBT1518_28660) - 5580457..5580696 (-) 240 WP_023523434.1 hypothetical protein -
  YBT1518_RS28195 (YBT1518_28665) - 5580696..5580932 (-) 237 WP_000398737.1 hemolysin XhlA family protein -
  YBT1518_RS28200 (YBT1518_28670) ltrA 5581034..5582308 (-) 1275 WP_023520826.1 group II intron reverse transcriptase/maturase -
  YBT1518_RS28205 - 5582898..5583301 (-) 404 Protein_5643 CHRD domain-containing protein -
  YBT1518_RS28215 (YBT1518_28685) - 5584618..5585007 (-) 390 WP_023523437.1 hypothetical protein -
  YBT1518_RS35915 (YBT1518_28690) - 5585025..5585147 (-) 123 WP_006921851.1 DUF3983 domain-containing protein -
  YBT1518_RS28220 (YBT1518_28695) - 5585316..5585510 (-) 195 WP_023523438.1 hypothetical protein -
  YBT1518_RS28225 (YBT1518_28700) - 5585965..5586510 (-) 546 WP_023523439.1 ERCC4 domain-containing protein -
  YBT1518_RS28230 (YBT1518_28705) - 5586501..5586935 (-) 435 WP_023523440.1 hypothetical protein -
  YBT1518_RS28235 (YBT1518_28710) - 5586923..5587147 (-) 225 WP_023523441.1 primase-like DNA-binding domain-containing protein -
  YBT1518_RS28240 (YBT1518_28715) - 5587418..5589772 (-) 2355 WP_023523442.1 phage/plasmid primase, P4 family -
  YBT1518_RS28245 (YBT1518_28720) - 5589845..5590321 (-) 477 WP_023523443.1 DUF669 domain-containing protein -
  YBT1518_RS28250 (YBT1518_28725) - 5590342..5591013 (-) 672 WP_043924723.1 AAA family ATPase -
  YBT1518_RS28255 (YBT1518_28730) - 5591019..5591210 (-) 192 WP_023521063.1 hypothetical protein -
  YBT1518_RS37215 - 5591207..5591392 (-) 186 WP_157447755.1 hypothetical protein -
  YBT1518_RS28265 (YBT1518_28735) - 5591681..5592028 (-) 348 WP_023523445.1 hypothetical protein -
  YBT1518_RS28270 (YBT1518_28740) - 5592327..5593520 (+) 1194 WP_023521170.1 IS110 family transposase -
  YBT1518_RS28275 - 5593600..5593779 (-) 180 WP_043924724.1 hypothetical protein -
  YBT1518_RS28280 (YBT1518_28745) - 5593838..5594071 (-) 234 WP_023523446.1 DUF771 domain-containing protein -
  YBT1518_RS28285 (YBT1518_28750) - 5594106..5594336 (-) 231 WP_023523447.1 helix-turn-helix transcriptional regulator -
  YBT1518_RS28290 (YBT1518_28755) - 5594501..5594893 (+) 393 WP_023523448.1 helix-turn-helix transcriptional regulator -
  YBT1518_RS28295 (YBT1518_28760) - 5594904..5595371 (+) 468 WP_043924725.1 hypothetical protein -
  YBT1518_RS28300 - 5595402..5596537 (+) 1136 Protein_5662 tyrosine-type recombinase/integrase -
  YBT1518_RS28310 (YBT1518_28775) - 5596952..5597158 (+) 207 WP_000216166.1 DUF1657 domain-containing protein -
  YBT1518_RS28315 (YBT1518_28780) - 5597252..5597737 (+) 486 WP_001228545.1 YhcN/YlaJ family sporulation lipoprotein -
  YBT1518_RS28320 (YBT1518_28785) spoVAC 5597767..5598243 (+) 477 WP_000095399.1 stage V sporulation protein AC -
  YBT1518_RS28325 (YBT1518_28790) spoVAD 5598244..5599260 (+) 1017 WP_000938970.1 stage V sporulation protein AD -
  YBT1518_RS28330 (YBT1518_28795) spoVAE 5599257..5599607 (+) 351 WP_000575919.1 stage V sporulation protein AE -
  YBT1518_RS28335 (YBT1518_28800) - 5599619..5599825 (+) 207 WP_000215897.1 DUF1657 domain-containing protein -
  YBT1518_RS28340 (YBT1518_28805) - 5599846..5600715 (+) 870 WP_000018924.1 DUF421 domain-containing protein -
  YBT1518_RS28345 (YBT1518_28810) clpP 5600956..5601537 (+) 582 WP_001049162.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21419.67 Da        Isoelectric Point: 5.0423

>NTDB_id=63643 YBT1518_RS28345 WP_001049162.1 5600956..5601537(+) (clpP) [Bacillus thuringiensis YBT-1518]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLESQDPEKDIHIYINSPGGSITAGMAIYDT
MQFIKPQVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILFLREKLNQILADRTGQ
PLEVLQRDTDRDNFMTAEKALEYGLIDKIFTNR

Nucleotide


Download         Length: 582 bp        

>NTDB_id=63643 YBT1518_RS28345 WP_001049162.1 5600956..5601537(+) (clpP) [Bacillus thuringiensis YBT-1518]
ATGAATTTAATTCCTACAGTAATTGAACAAACAAATCGTGGAGAACGCGCTTACGATATTTACTCTCGACTATTAAAAGA
CCGCATCATTATGCTTGGTAGTGCAATTGATGACAACGTAGCTAACTCAATCGTTTCCCAGCTTTTATTCTTGGAATCTC
AAGATCCAGAAAAAGATATTCACATCTACATCAACAGCCCTGGTGGTTCTATCACAGCGGGTATGGCAATCTATGATACA
ATGCAGTTTATTAAACCACAAGTATCAACAATCTGTATCGGTATGGCTGCATCTATGGGTGCATTCTTACTTGCAGCAGG
TGAAAAAGGAAAACGTTACGCACTTCCAAACAGTGAAGTAATGATTCACCAACCACTTGGTGGAGCACAAGGTCAAGCGA
CTGAAATCGAAATCGCTGCAAAACGTATCCTATTCTTACGTGAAAAACTAAACCAAATTCTTGCTGACCGCACTGGTCAA
CCACTTGAAGTACTACAACGCGACACAGACCGCGACAACTTCATGACAGCGGAAAAAGCTTTAGAATACGGTTTAATCGA
TAAGATCTTTACAAATCGTTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

90.104

99.482

0.896
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

67.021

97.409

0.653
  clpP Streptococcus thermophilus LMG 18311

60.417

99.482

0.601
  clpP Streptococcus thermophilus LMD-9

60.417

99.482

0.601
  clpP Lactococcus lactis subsp. cremoris KW2

58.854

99.482

0.585
  clpP Streptococcus pneumoniae D39

57.292

99.482

0.57
  clpP Streptococcus pneumoniae Rx1

57.292

99.482

0.57
  clpP Streptococcus pneumoniae R6

57.292

99.482

0.57
  clpP Streptococcus pneumoniae TIGR4

57.292

99.482

0.57
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

56.771

99.482

0.565
  clpP Streptococcus pyogenes JRS4

55.729

99.482

0.554
  clpP Streptococcus pyogenes MGAS315

55.729

99.482

0.554
  clpP Streptococcus mutans UA159

55.44

100

0.554

Multiple sequence alignment