NTDB

Overview

Name	comYB	Type	Machinery gene
Locus tag	CSB63_RS08985	Genome accession	NZ_CP089060
Coordinates	1693716..1694816 (-)	Length	366 a.a.
NCBI ID	WP_134973504.1	Uniprot ID	-
Organism	Streptococcus thermophilus strain CH8
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1688716..1699816

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSB63_RS08945 (CSB63_1883)	-	1689328..1689525 (-)	198	WP_014727723.1	helix-turn-helix transcriptional regulator	-
CSB63_RS08950 (CSB63_1884)	-	1689774..1690967 (-)	1194	WP_014608740.1	acetate kinase	-
CSB63_RS08955 (CSB63_1885)	comYH	1691023..1691979 (-)	957	WP_011681684.1	class I SAM-dependent methyltransferase	Machinery gene
CSB63_RS08960 (CSB63_1886)	comGG	1692024..1692341 (-)	318	WP_011681685.1	competence type IV pilus minor pilin ComGG	-
CSB63_RS08965 (CSB63_1887)	comYF	1692319..1692756 (-)	438	WP_011681686.1	competence type IV pilus minor pilin ComGF	Machinery gene
CSB63_RS08970	comGE	1692740..1693033 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
CSB63_RS08975 (CSB63_1889)	comYD	1693005..1693433 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
CSB63_RS08980 (CSB63_1890)	comYC	1693393..1693719 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
CSB63_RS08985 (CSB63_1891)	comYB	1693716..1694816 (-)	1101	WP_134973504.1	competence type IV pilus assembly protein ComGB	Machinery gene
CSB63_RS08990 (CSB63_1892)	-	1694698..1695390 (-)	693	Protein_1709	ATPase, T2SS/T4P/T4SS family	-
CSB63_RS08995 (CSB63_1893)	-	1695448..1696800 (-)	1353	WP_134973005.1	IS66-like element short variant transposase	-
CSB63_RS09000 (CSB63_1894)	-	1696754..1696960 (-)	207	WP_134973004.1	transposase	-
CSB63_RS09005 (CSB63_1895)	tnpB	1697011..1697361 (-)	351	WP_014295152.1	IS66 family insertion sequence element accessory protein TnpB	-
CSB63_RS09010 (CSB63_1896)	-	1697342..1697527 (-)	186	WP_134973003.1	hypothetical protein	-
CSB63_RS09015 (CSB63_1897)	-	1697609..1697875 (-)	267	Protein_1714	hypothetical protein	-
CSB63_RS09020 (CSB63_1898)	-	1697956..1698318 (-)	363	WP_014622006.1	DUF1033 family protein	-

Sequence

Protein

Download Length: 366 a.a. Molecular weight: 41804.94 Da Isoelectric Point: 10.0168

                                >NTDB_id=634896 CSB63_RS08985 WP_134973504.1 1693716..1694816(-) (comYB) [Streptococcus thermophilus strain CH8]

MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKETSLSLM

KESLIRGDRLYQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN

YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRIAKIPFIGQTVRLYTTAYYAREWG

NLLGQGVDLLDLVALMQEQKSKLFCELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW

QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide

Download Length: 1101 bp

                                >NTDB_id=634896 CSB63_RS08985 WP_134973504.1 1693716..1694816(-) (comYB) [Streptococcus thermophilus strain CH8]

TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC

ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTCATCCAGCTCTTCAAACAACTTTTAA

AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAACATCCTTGTCTCTTATG

AAAGAGAGTTTAATACGCGGTGATAGGTTGTATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT

TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC

GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT

TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT

TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT

ATAGGCGAATAGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA

AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCTGTGAGCT

GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCAGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG

AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG

CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT

AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comYB	Streptococcus mutans UA140	54.386	93.443	0.508
comYB	Streptococcus mutans UA159	54.386	93.443	0.508
comYB	Streptococcus gordonii str. Challis substr. CH1	51.17	93.443	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	50.453	90.437	0.456
comGB/cglB	Streptococcus mitis SK321	49.697	90.164	0.448
comGB/cglB	Streptococcus pneumoniae Rx1	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae D39	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae R6	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae TIGR4	49.394	90.164	0.445
comGB	Lactococcus lactis subsp. cremoris KW2	45.758	90.164	0.413

Detailed information NTG0634896