Detailed information NTG0631055

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: LP473_RS08595
• Genome accession: NZ_CP087699
• Coordinates: 1763835..1764452 (-)
• Length: 205 a.a.
• NCBI ID: WP_252174699.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain IBB417
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1758835..1769452

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LP473_RS08570 (LP473_08575)	atpF	1758876..1759382 (-)	507	WP_004255258.1	F0F1 ATP synthase subunit B	-
LP473_RS08575 (LP473_08580)	atpB	1759397..1760110 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
LP473_RS08580 (LP473_08585)	-	1760155..1760370 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
LP473_RS08585 (LP473_08590)	-	1760554..1761330 (-)	777	WP_252174698.1	alpha/beta hydrolase family protein	-
LP473_RS08590 (LP473_08595)	-	1761615..1763824 (-)	2210	Protein_1674	DNA internalization-related competence protein ComEC/Rec2	-
LP473_RS08595 (LP473_08600)	comEA	1763835..1764452 (-)	618	WP_252174699.1	ComEA family DNA-binding protein	Machinery gene
LP473_RS08600 (LP473_08605)	-	1764512..1765873 (-)	1362	WP_252174700.1	ABC transporter permease	-
LP473_RS08605 (LP473_08610)	-	1765870..1766802 (-)	933	WP_004255238.1	ABC transporter ATP-binding protein	-
LP473_RS08610 (LP473_08615)	-	1766907..1767305 (-)	399	WP_004255236.1	hypothetical protein	-
LP473_RS08615 (LP473_08620)	-	1767409..1767972 (-)	564	WP_004255233.1	GNAT family N-acetyltransferase	-
LP473_RS08620 (LP473_08625)	-	1768145..1769323 (-)	1179	WP_021214596.1	SLC13 family permease	-

Sequence

Protein

• Length: 205 a.a.
• Molecular weight: 22416.41 Da
• Isoelectric Point: 5.4439

>NTDB_id=631055 LP473_RS08595 WP_252174699.1 1763835..1764452(-) (comEA) [Lactococcus lactis subsp. lactis strain IBB417]
MDKILEKVKEYWKMIVLVVCGLIAGGIFYVLTNGQKPTTNLSVENLSSVSRQSSVSKFSEPNEKSVSKIMVDLKGAVTKP
NVYQISSDERLVDLIKEAGGFTDQADQKSINLSAKLKDEEVIYVPKIGENSSTENTDSSANSVTSQVSKTTEKININQAD
LTELQKLTGVGQKKAQDIIDFRTKNGDFKSLEDLGKVSGFGDKTL

Nucleotide

• Length: 618 bp

>NTDB_id=631055 LP473_RS08595 WP_252174699.1 1763835..1764452(-) (comEA) [Lactococcus lactis subsp. lactis strain IBB417]
ATGGATAAGATTTTAGAAAAAGTAAAAGAATATTGGAAAATGATTGTTTTAGTTGTTTGTGGGCTCATTGCTGGTGGGAT
TTTTTACGTTTTAACCAACGGTCAAAAGCCAACTACAAATCTGTCAGTAGAAAATTTAAGTTCTGTCAGCAGGCAAAGCT
CTGTCAGTAAATTTAGTGAACCTAATGAAAAATCTGTCAGTAAAATTATGGTTGATTTAAAAGGTGCGGTAACAAAGCCT
AATGTCTATCAAATTTCGTCAGATGAACGTCTAGTTGATTTAATTAAAGAAGCTGGTGGTTTTACTGACCAAGCTGACCA
GAAATCAATTAATCTGTCAGCAAAATTAAAAGATGAAGAAGTAATTTATGTCCCAAAAATTGGTGAAAATTCAAGCACAG
AAAATACTGACAGCTCTGCTAATTCGGTCACTAGTCAAGTCTCAAAAACCACTGAAAAAATAAATATCAATCAAGCAGAT
TTGACTGAACTACAAAAATTAACAGGTGTTGGTCAGAAAAAAGCTCAAGACATCATCGATTTTCGGACGAAAAATGGTGA
TTTCAAATCACTTGAAGACTTGGGAAAAGTTTCTGGTTTTGGAGATAAAACACTATAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (151-205)

• SLBB domain (SLBB) (70-125)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Lactococcus lactis subsp. cremoris KW2	76.442	100	0.776
comEA/celA/cilE	Streptococcus mitis SK321	43.602	100	0.449
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	42.254	100	0.439
comEA/celA/cilE	Streptococcus mitis NCTC 12261	40.376	100	0.42
comEA/celA/cilE	Streptococcus pneumoniae Rx1	40.187	100	0.42
comEA/celA/cilE	Streptococcus pneumoniae D39	40.187	100	0.42
comEA/celA/cilE	Streptococcus pneumoniae R6	40.187	100	0.42
comEA	Latilactobacillus sakei subsp. sakei 23K	36.53	100	0.39
comEA	Staphylococcus aureus MW2	36.364	100	0.371