Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   N596_RS01385 Genome accession   NC_022584
Coordinates   263890..264564 (+) Length   224 a.a.
NCBI ID   WP_023022847.1    Uniprot ID   -
Organism   Streptococcus ilei     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 258890..269564
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N596_RS01365 (N596_01410) phoU 259054..259707 (+) 654 WP_023026661.1 phosphate signaling complex protein PhoU -
  N596_RS01370 (N596_01415) - 259838..262381 (+) 2544 WP_042361033.1 M1 family metallopeptidase -
  N596_RS01375 (N596_01420) - 262438..262980 (-) 543 WP_042361035.1 biotin transporter BioY -
  N596_RS01380 (N596_01425) - 263186..263776 (+) 591 WP_023026663.1 hypothetical protein -
  N596_RS01385 (N596_01430) ciaR 263890..264564 (+) 675 WP_023022847.1 response regulator transcription factor Regulator
  N596_RS01390 (N596_01435) ciaH 264554..265927 (+) 1374 WP_023022849.1 cell wall metabolism sensor histidine kinase WalK Regulator
  N596_RS01395 (N596_01440) - 266293..266679 (+) 387 WP_023022851.1 VOC family protein -
  N596_RS01400 (N596_01445) - 266874..268259 (+) 1386 WP_023026664.1 polysaccharide deacetylase family protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25338.07 Da        Isoelectric Point: 4.3373

>NTDB_id=62945 N596_RS01385 WP_023022847.1 263890..264564(+) (ciaR) [Streptococcus ilei]
MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGDEGLYEAESGIYDLILLDLMLPEKDGFQVLKELRDKGVSTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKVNENTLSYGNVTVNLSTNSTLVEGKEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTEFAKNLQTLRSVGYILKDAQ

Nucleotide


Download         Length: 675 bp        

>NTDB_id=62945 N596_RS01385 WP_023022847.1 263890..264564(+) (ciaR) [Streptococcus ilei]
ATGATTAAGATTTTATTAGTAGAAGACGACCTCGGTTTGTCTAATTCAGTATTTGATTTTTTAGATGACTTTGCAGATGT
CATGCAAGTCTTTGATGGAGACGAAGGTCTTTATGAGGCTGAAAGTGGCATCTATGACCTCATTTTGCTAGACCTCATGC
TCCCTGAAAAAGATGGTTTCCAAGTTCTGAAAGAATTGAGAGATAAGGGTGTCTCCACTCCAGTATTGATTATGACAGCC
AAAGAGAGTTTGGACGATAAGGGCCATGGGTTTGAGTTAGGGGCAGATGACTATCTGACCAAGCCATTCTACCTAGAAGA
ACTCAAGATGCGGATCCAAGCATTGTTGAAGCGCTCTGGTAAGGTCAATGAAAATACCCTTTCTTATGGGAATGTAACCG
TTAATCTTTCGACAAATTCTACGCTTGTTGAAGGGAAAGAAGTGGAGCTATTAGGGAAAGAATTTGATCTTTTGGTCTAT
TTCCTTCAAAATCAAAATGTTATCCTGCCCAAGACACAAATCTTTGATCGACTTTGGGGATTTGATAGCGATACGACTAT
CTCGGTTGTTGAAGTGTATGTTTCTAAGATTCGTAAGAAGTTAAAAGGAACAGAATTTGCAAAAAATCTCCAAACATTGC
GTAGCGTGGGGTACATTCTGAAAGATGCTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

90.625

100

0.906
  ciaR Streptococcus pneumoniae D39

90.625

100

0.906
  ciaR Streptococcus pneumoniae R6

90.625

100

0.906
  ciaR Streptococcus pneumoniae TIGR4

90.625

100

0.906
  ciaR Streptococcus mutans UA159

87.946

100

0.879
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.428

100

0.393
  vicR Streptococcus mutans UA159

35.622

100

0.371
  covR Streptococcus salivarius strain HSISS4

35.841

100

0.362

Multiple sequence alignment