Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   N596_RS01390 Genome accession   NC_022584
Coordinates   264554..265927 (+) Length   457 a.a.
NCBI ID   WP_023022849.1    Uniprot ID   -
Organism   Streptococcus ilei     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 259554..270927
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N596_RS01370 (N596_01415) - 259838..262381 (+) 2544 WP_042361033.1 M1 family metallopeptidase -
  N596_RS01375 (N596_01420) - 262438..262980 (-) 543 WP_042361035.1 biotin transporter BioY -
  N596_RS01380 (N596_01425) - 263186..263776 (+) 591 WP_023026663.1 hypothetical protein -
  N596_RS01385 (N596_01430) ciaR 263890..264564 (+) 675 WP_023022847.1 response regulator transcription factor Regulator
  N596_RS01390 (N596_01435) ciaH 264554..265927 (+) 1374 WP_023022849.1 cell wall metabolism sensor histidine kinase WalK Regulator
  N596_RS01395 (N596_01440) - 266293..266679 (+) 387 WP_023022851.1 VOC family protein -
  N596_RS01400 (N596_01445) - 266874..268259 (+) 1386 WP_023026664.1 polysaccharide deacetylase family protein -
  N596_RS01405 (N596_01450) - 268572..269657 (-) 1086 WP_023026665.1 DEAD/DEAH box helicase -
  N596_RS01410 (N596_01455) - 269659..270636 (-) 978 WP_023026666.1 Gfo/Idh/MocA family protein -

Sequence

Protein


Download         Length: 457 a.a.        Molecular weight: 52509.81 Da        Isoelectric Point: 6.5330

>NTDB_id=62946 N596_RS01390 WP_023022849.1 264554..265927(+) (ciaH) [Streptococcus ilei]
MLNKIKKTVNADDFSYFIRYFGLFTLIFSTMTLIIIQVMRSSLYTTVDENLKILSKDRYSIISLANRTGNGMGRDEPDDD
RPEDNEPDPEDGPRPSVTSNSTAILLNDNFENVTTDNGFLDLKTVTFSRSYLNKIKQIQITNHYKQKESYRAYLVDIDPD
DYIDGVKYAVIMTNISQLEQTSEKHESQIALVMICFWGISLFASIFLAKMSVKPLLESMNRQKAFVENASHELRTPLAVL
QNRLETLFRKPEATIMESSENIASSLDEVRNMRLLTTNLLNLARRDDGIKPEFCEIPPSFFDQTFANYEIIAEENDKIFE
YENHVERSLVSDKVLLKQLMTILYDNALKYTEEEGKIRFVAQFKDRYLYLRVEDNGPGIADEDKKRIFDRFYRVDKARTR
QKGGFGLGLSLAKQIVEAFNGTITVRDNKPKGAIFEVKLATKSDSKKKSTSKSTKNK

Nucleotide


Download         Length: 1374 bp        

>NTDB_id=62946 N596_RS01390 WP_023022849.1 264554..265927(+) (ciaH) [Streptococcus ilei]
ATGCTCAATAAAATTAAAAAAACTGTCAATGCGGATGACTTTTCTTATTTCATCCGCTATTTCGGACTCTTTACCTTGAT
TTTCTCAACCATGACCTTGATTATTATTCAAGTAATGCGGTCAAGTCTGTATACAACGGTTGATGAAAATTTAAAGATAC
TGAGTAAAGATCGTTATTCCATCATTAGCTTGGCCAATCGTACCGGAAATGGGATGGGAAGAGACGAACCAGATGATGAC
CGACCAGAAGATAATGAACCTGATCCCGAGGATGGCCCTAGACCATCGGTCACTTCCAATAGTACAGCCATCCTCTTGAA
TGATAATTTTGAAAATGTGACGACGGACAATGGTTTTCTGGATTTAAAAACAGTGACCTTTAGTCGCAGCTATTTAAACA
AGATCAAGCAGATTCAAATCACCAACCATTATAAGCAAAAAGAAAGCTACCGGGCTTATTTGGTGGATATTGACCCCGAT
GATTATATCGATGGGGTGAAATATGCCGTGATCATGACCAATATCAGCCAGTTGGAGCAGACCAGTGAAAAACACGAGAG
CCAAATCGCCTTGGTCATGATTTGCTTCTGGGGCATTTCCCTCTTTGCAAGTATCTTCCTGGCTAAGATGAGTGTGAAAC
CTCTCTTAGAGAGCATGAACCGGCAGAAGGCTTTTGTCGAAAATGCTTCTCATGAATTGCGGACACCTTTAGCCGTTTTG
CAAAATCGTTTGGAAACCCTGTTCCGAAAGCCAGAGGCAACAATTATGGAATCCAGTGAGAATATCGCCTCCTCTTTGGA
TGAGGTTCGCAATATGCGCTTACTGACGACCAATCTCTTAAACTTAGCCCGTCGAGATGATGGGATTAAACCTGAGTTTT
GTGAAATCCCTCCTTCTTTTTTCGACCAAACCTTTGCCAATTATGAAATCATTGCCGAGGAAAATGATAAAATCTTCGAG
TATGAGAATCATGTCGAAAGGAGTCTGGTGTCTGACAAGGTCCTACTGAAACAGCTGATGACCATTTTGTATGACAATGC
CCTCAAATACACAGAGGAAGAAGGAAAGATACGGTTTGTCGCCCAATTCAAGGATCGCTATCTCTATCTTCGGGTAGAGG
ATAATGGACCAGGGATTGCAGACGAAGATAAAAAGCGGATATTTGATCGATTCTACCGAGTGGATAAGGCGCGTACGCGT
CAAAAGGGTGGTTTTGGTTTAGGACTGTCCTTAGCCAAGCAAATCGTAGAAGCCTTTAATGGCACCATTACTGTTCGAGA
TAACAAGCCGAAAGGTGCTATTTTCGAGGTCAAACTAGCAACCAAGTCAGATAGTAAAAAGAAATCAACTTCTAAATCAA
CGAAAAACAAGTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(223-288)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(332-439)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

60.356

98.249

0.593
  ciaH Streptococcus pneumoniae D39

60.356

98.249

0.593
  ciaH Streptococcus pneumoniae R6

60.356

98.249

0.593
  ciaH Streptococcus pneumoniae TIGR4

60.356

98.249

0.593
  ciaH Streptococcus mutans UA159

50.342

96.061

0.484

Multiple sequence alignment