Detailed information NTG0062522

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: N288_RS20080
• Genome accession: NC_022524
• Coordinates: 3971231..3971836 (+)
• Length: 201 a.a.
• NCBI ID: WP_009793069.1
• Uniprot ID: U5LHW0
• Organism: Bacillus infantis NRRL B-14911
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3966231..3976836

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
N288_RS20055 (N288_21610)	-	3967249..3968271 (-)	1023	WP_009793074.1	sugar-binding transcriptional regulator	-
N288_RS20060 (N288_21615)	-	3968424..3968678 (-)	255	WP_224949684.1	glutaredoxin family protein	-
N288_RS20065 (N288_21620)	rpoN	3968696..3970027 (-)	1332	WP_009793072.1	RNA polymerase factor sigma-54	-
N288_RS20075 (N288_21635)	-	3970390..3970896 (-)	507	WP_022544379.1	DUF6241 domain-containing protein	-
N288_RS20080 (N288_21640)	clpP	3971231..3971836 (+)	606	WP_009793069.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
N288_RS20085 (N288_21645)	-	3971952..3972209 (-)	258	WP_009793068.1	HPr family phosphocarrier protein	-
N288_RS20090 (N288_21650)	whiA	3972240..3973190 (-)	951	WP_009793067.1	DNA-binding protein WhiA	-
N288_RS20095 (N288_21655)	yvcK	3973232..3974215 (-)	984	WP_009793066.1	uridine diphosphate-N-acetylglucosamine-binding protein YvcK	-
N288_RS20100 (N288_21660)	rapZ	3974212..3975105 (-)	894	WP_009793065.1	RNase adapter RapZ	-
N288_RS20105 (N288_21665)	-	3975135..3975593 (-)	459	WP_009793064.1	8-oxo-dGTP diphosphatase	-

Sequence

Protein

• Length: 201 a.a.
• Molecular weight: 22276.68 Da
• Isoelectric Point: 4.9325

>NTDB_id=62522 N288_RS20080 WP_009793069.1 3971231..3971836(+) (clpP) [Bacillus infantis NRRL B-14911]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVSNSIVAQLLFLEAENPEKDITLYINSPGGSITAGMAIYDT
MQYIRPKVSTVCIGMAASMGAFLLAAGEKGKRFALPNSEVMIHQPLGGAQGQATEIEIAAKRILFLREKLNQILSERTGQ
PLEVIAKDTDRDNFMTAERALEYGLIDQIISRNVLEEKKDK

Nucleotide

• Length: 606 bp

>NTDB_id=62522 N288_RS20080 WP_009793069.1 3971231..3971836(+) (clpP) [Bacillus infantis NRRL B-14911]
ATGAATTTAATCCCTACAGTTATTGAACAGACAAACAGGGGCGAGCGCGCATACGATATTTATTCACGCCTTCTGAAAGA
CCGCATCATCATGCTTGGTAGTGCGATCGATGATAATGTGTCAAACTCCATTGTAGCTCAGCTGCTATTCCTGGAAGCAG
AAAACCCTGAAAAGGATATCACTTTGTACATCAACAGCCCTGGCGGCAGCATCACTGCCGGTATGGCGATTTATGATACG
ATGCAGTACATCCGTCCGAAGGTTTCCACAGTCTGCATCGGGATGGCCGCTTCCATGGGTGCATTCCTTCTGGCAGCAGG
CGAGAAAGGCAAGCGTTTTGCCCTTCCAAACAGTGAAGTCATGATCCATCAGCCGCTGGGCGGAGCTCAGGGCCAGGCAA
CAGAAATCGAAATTGCCGCAAAGCGCATTCTTTTCCTTCGCGAAAAGCTCAACCAAATTCTTTCAGAACGCACAGGCCAG
CCGCTTGAAGTGATCGCTAAGGATACTGACCGCGACAACTTCATGACAGCTGAGAGAGCATTGGAATACGGCCTGATCGA
CCAGATCATCAGCCGCAATGTCCTGGAAGAAAAGAAAGACAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: U5LHW0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	85.93	99.005	0.851
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	67.539	95.025	0.642
clpP	Lactococcus lactis subsp. cremoris KW2	57.143	97.512	0.557
clpP	Streptococcus thermophilus LMG 18311	57.143	97.512	0.557
clpP	Streptococcus thermophilus LMD-9	57.143	97.512	0.557
clpP	Streptococcus pneumoniae D39	55.897	97.015	0.542
clpP	Streptococcus pneumoniae Rx1	55.897	97.015	0.542
clpP	Streptococcus pneumoniae R6	55.897	97.015	0.542
clpP	Streptococcus pneumoniae TIGR4	55.897	97.015	0.542
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.102	97.512	0.537
clpP	Streptococcus mutans UA159	54.822	98.01	0.537
clpP	Streptococcus pyogenes JRS4	54.592	97.512	0.532
clpP	Streptococcus pyogenes MGAS315	54.592	97.512	0.532