Detailed information NTG0622431

Bioinformatically predicted

Overview

• Name: covR
• Type: Regulator
• Locus tag: LL046_RS07555
• Genome accession: NZ_CP086088
• Coordinates: 1539620..1540312 (-)
• Length: 230 a.a.
• NCBI ID: WP_012898209.1
• Uniprot ID: A0AAW7IPJ0
• Organism: Lactococcus lactis subsp. lactis strain EIP13A
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1534620..1545312

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LL046_RS07540 (LL046_07520)	-	1536239..1536580 (-)	342	WP_010906046.1	P-II family nitrogen regulator	-
LL046_RS07545 (LL046_07525)	-	1536712..1537953 (-)	1242	WP_012898207.1	ammonium transporter	-
LL046_RS07550 (LL046_07530)	covS	1538136..1539611 (-)	1476	WP_240819078.1	HAMP domain-containing histidine kinase	Regulator
LL046_RS07555 (LL046_07535)	covR	1539620..1540312 (-)	693	WP_012898209.1	response regulator transcription factor	Regulator
LL046_RS07560 (LL046_07540)	-	1540468..1540998 (-)	531	WP_012898210.1	DUF177 domain-containing protein	-
LL046_RS07565 (LL046_07545)	-	1541129..1541374 (-)	246	WP_003130760.1	type B 50S ribosomal protein L31	-
LL046_RS07570 (LL046_07550)	-	1541530..1541994 (-)	465	WP_240819076.1	hypothetical protein	-
LL046_RS07575 (LL046_07555)	-	1542076..1542438 (-)	363	WP_211752483.1	TIGR02328 family protein	-
LL046_RS07580 (LL046_07560)	-	1542922..1543419 (-)	498	WP_235585826.1	CHAP domain-containing protein	-
LL046_RS07585 (LL046_07565)	-	1543513..1544349 (-)	837	WP_017864800.1	metallophosphoesterase	-

Sequence

Protein

• Length: 230 a.a.
• Molecular weight: 26670.33 Da
• Isoelectric Point: 5.1273

>NTDB_id=622431 LL046_RS07555 WP_012898209.1 1539620..1540312(-) (covR) [Lactococcus lactis subsp. lactis strain EIP13A]
MTSKKILIIEDEKNLARFVSLELEHEGYATEIKDNGRSGLEEASSKDYDLILLDLMLPELDGFEVARRLRKEKDTPIIMM
TARDSTMDRVAGLDIGADDYITKPFAIEELLARVRAFFRREEHGHAVERAENTSFRDLVIDKTNRTVHRGKKVIDLTRRE
YDLLLTLMQNVGDVVTREHLVSQVWGYEEGTETNVVDVYIRYLRNKIDVEGQDSYIQTVRGLGYVMRERK

Nucleotide

• Length: 693 bp

>NTDB_id=622431 LL046_RS07555 WP_012898209.1 1539620..1540312(-) (covR) [Lactococcus lactis subsp. lactis strain EIP13A]
ATGACTTCAAAGAAAATTTTGATTATTGAGGATGAAAAGAATTTAGCGCGATTCGTCTCATTAGAATTAGAACATGAAGG
CTATGCGACTGAGATTAAAGATAATGGTCGTTCTGGTCTTGAAGAAGCAAGTTCAAAAGATTATGATTTAATCTTGCTTG
ATTTGATGCTTCCTGAACTTGACGGTTTTGAGGTAGCTCGTCGTTTACGAAAAGAAAAAGATACACCAATCATTATGATG
ACGGCACGTGATTCAACGATGGACCGTGTTGCTGGTCTTGATATTGGGGCTGATGATTATATCACTAAACCTTTTGCGAT
TGAGGAACTTTTGGCGCGTGTTCGTGCTTTCTTCCGTCGTGAAGAGCATGGTCATGCCGTTGAACGTGCTGAAAATACTT
CTTTCCGTGATCTTGTGATTGACAAAACGAATCGCACCGTTCATCGTGGTAAAAAAGTAATTGATTTAACACGTCGTGAG
TATGACCTCCTTTTGACATTGATGCAAAATGTTGGCGATGTTGTGACTCGTGAACATTTAGTTTCACAAGTTTGGGGATA
TGAAGAAGGAACAGAAACAAATGTTGTGGATGTTTATATTCGTTATCTTAGAAATAAAATTGATGTTGAAGGTCAAGATA
GCTATATTCAAACTGTTCGTGGCTTAGGTTATGTAATGCGTGAACGCAAATAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (153-226)

• Response regulator receiver domain (Response_reg) (6-115)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covR	Lactococcus lactis subsp. lactis strain DGCC12653	99.565	100	0.996
covR	Streptococcus salivarius strain HSISS4	68.421	99.13	0.678
vicR	Streptococcus mutans UA159	45.887	100	0.461
micA	Streptococcus pneumoniae Cp1015	43.478	100	0.435
ciaR	Streptococcus mutans UA159	37.611	98.261	0.37
ciaR	Streptococcus pneumoniae Rx1	36.726	98.261	0.361
ciaR	Streptococcus pneumoniae D39	36.726	98.261	0.361
ciaR	Streptococcus pneumoniae R6	36.726	98.261	0.361
ciaR	Streptococcus pneumoniae TIGR4	36.726	98.261	0.361