Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   HIFGL_RS00210 Genome accession   NC_022356
Coordinates   44170..45513 (+) Length   447 a.a.
NCBI ID   WP_021034382.1    Uniprot ID   -
Organism   Haemophilus influenzae KR494     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 39170..50513
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HIFGL_RS00185 (HifGL_000036) - 39229..41829 (-) 2601 WP_021034377.1 penicillin-binding protein 1A -
  HIFGL_RS00190 (HifGL_000037) comA 41928..42725 (+) 798 WP_021034378.1 pilus assembly protein PilM Machinery gene
  HIFGL_RS00195 (HifGL_000038) comB 42726..43232 (+) 507 WP_021034379.1 hypothetical protein Machinery gene
  HIFGL_RS00200 (HifGL_000039) comC 43229..43750 (+) 522 WP_021034380.1 hypothetical protein Machinery gene
  HIFGL_RS00205 (HifGL_000040) comD 43747..44160 (+) 414 WP_021034381.1 pilus assembly protein PilP Machinery gene
  HIFGL_RS00210 (HifGL_000041) comE 44170..45513 (+) 1344 WP_021034382.1 type IV pilus secretin PilQ Machinery gene
  HIFGL_RS00215 tnpA 45510..45963 (+) 454 Protein_42 IS200/IS605 family transposase -
  HIFGL_RS00220 (HifGL_000043) - 46211..46897 (+) 687 WP_021034384.1 ComF family protein -
  HIFGL_RS00225 (HifGL_000044) nfuA 46973..47569 (+) 597 WP_021034385.1 Fe-S biogenesis protein NfuA -
  HIFGL_RS00230 (HifGL_000045) nudC 47637..48431 (+) 795 WP_021034386.1 NAD(+) diphosphatase -
  HIFGL_RS00235 (HifGL_000046) - 48467..49057 (+) 591 WP_021034387.1 YjaG family protein -
  HIFGL_RS00240 (HifGL_000047) - 49196..49468 (+) 273 WP_005630954.1 HU family DNA-binding protein -

Sequence

Protein


Download         Length: 447 a.a.        Molecular weight: 49516.68 Da        Isoelectric Point: 6.7046

>NTDB_id=62152 HIFGL_RS00210 WP_021034382.1 44170..45513(+) (comE) [Haemophilus influenzae KR494]
MKKYFLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQQDVNLVIDEALESNISLRLDNIDMPRLLQ
IIAKSKKLTLNKDEGIYYLNGGQSGKWQVAGNLTTNEPHLESHTVKLHFAKASELMKSLTTGSGSLLSSAGSITFDDRSN
LLVIQDEPHSVQNIKKLISEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLAGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVSYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKKLQ

Nucleotide


Download         Length: 1344 bp        

>NTDB_id=62152 HIFGL_RS00210 WP_021034382.1 44170..45513(+) (comE) [Haemophilus influenzae KR494]
ATGAAGAAATATTTTTTAAAGTGCGGTTATTTTTTAGTCTGTTTTTGTTTACCCTTAATTGTTTTTGCTAATCCCAAAAC
TGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCTCAAACATTAGAGCAGTTGGCTTTTCAACAAGATG
TGAATTTAGTGATAGATGAAGCATTAGAAAGTAATATTTCATTGAGATTAGATAATATTGATATGCCACGTTTACTACAA
ATAATCGCTAAAAGTAAGAAGCTTACTTTGAATAAAGATGAGGGTATTTACTATCTGAATGGAGGGCAATCAGGCAAATG
GCAAGTTGCAGGAAATCTTACTACAAATGAACCGCACTTAGAGAGCCATACAGTAAAACTCCATTTTGCTAAAGCCTCTG
AATTAATGAAGTCCTTAACGACAGGAAGTGGCTCTTTGCTTTCATCAGCTGGGAGCATTACCTTTGATGATCGTAGTAAT
TTGCTCGTGATTCAAGATGAACCTCATTCTGTGCAAAATATCAAAAAACTAATTTCTGAAATGGATAAACCTATTGAGCA
GATTGCTATTGAAGCGCGTATTGTGACGATAACAGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACGGAAAATGCAAGACGAGTTGCGGGCAGTCTTGCAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACAACACCTGCTGGCTCGATAGCATTACAAGTCGCCAAAATTAATGGGCGATTGCTCGATTTAGAATT
GAGTGCGTTAGAGCGTGAAAATAATGTAGAAATTATCGCAAGCCCTCGCTTACTAACCACAAATAAGAAAAGTGCAAGCA
TTAAACAGGGGACAGAAATTCCTTATATTGTGAGCAATACTCGTAACGATACGCAATCTGTGGAATTTCGCGAGGCGGTG
CTTGGTTTGGAAGTCACACCACATATTTCTAAAGATAACAATATTTTACTTGATTTATTAGTGAGCCAAAACTCACCAGG
TTCTCGTGTTTCTTATGGACAAAATGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTGTTTCACGACACAATTACGAAAAGCGAAGATAAGGTGCCATTGCTTGGCGATATA
CCCGTTATTAAACGATTATTCAGCAAAGAAAGCGAACGACATCAAAAACGTGAGCTCGTGATTTTCGTGACGCCGCATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAGCAAAAAAGTGCGGGGAAAAAGTTACAATGA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)

Bacterial type II and III secretion system protein (Secretin)

(269-429)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

95.955

99.553

0.955
  comE Haemophilus influenzae 86-028NP

95.73

99.553

0.953
  comE Glaesserella parasuis strain SC1401

52.941

95.078

0.503
  pilQ Vibrio campbellii strain DS40M4

42.959

93.736

0.403
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.233

92.17

0.389
  pilQ Vibrio cholerae strain A1552

42.233

92.17

0.389

Multiple sequence alignment