Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   HIFGL_RS00190 Genome accession   NC_022356
Coordinates   41928..42725 (+) Length   265 a.a.
NCBI ID   WP_021034378.1    Uniprot ID   -
Organism   Haemophilus influenzae KR494     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 36928..47725
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HIFGL_RS00170 (HifGL_000033) recR 37094..37696 (-) 603 WP_021034375.1 recombination mediator RecR -
  HIFGL_RS00175 (HifGL_000034) - 37829..38158 (-) 330 WP_005629464.1 YbaB/EbfC family nucleoid-associated protein -
  HIFGL_RS00180 (HifGL_000035) - 38310..39155 (-) 846 WP_021034376.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  HIFGL_RS00185 (HifGL_000036) - 39229..41829 (-) 2601 WP_021034377.1 penicillin-binding protein 1A -
  HIFGL_RS00190 (HifGL_000037) comA 41928..42725 (+) 798 WP_021034378.1 pilus assembly protein PilM Machinery gene
  HIFGL_RS00195 (HifGL_000038) comB 42726..43232 (+) 507 WP_021034379.1 hypothetical protein Machinery gene
  HIFGL_RS00200 (HifGL_000039) comC 43229..43750 (+) 522 WP_021034380.1 hypothetical protein Machinery gene
  HIFGL_RS00205 (HifGL_000040) comD 43747..44160 (+) 414 WP_021034381.1 pilus assembly protein PilP Machinery gene
  HIFGL_RS00210 (HifGL_000041) comE 44170..45513 (+) 1344 WP_021034382.1 type IV pilus secretin PilQ Machinery gene
  HIFGL_RS00215 tnpA 45510..45963 (+) 454 Protein_42 IS200/IS605 family transposase -
  HIFGL_RS00220 (HifGL_000043) - 46211..46897 (+) 687 WP_021034384.1 ComF family protein -
  HIFGL_RS00225 (HifGL_000044) nfuA 46973..47569 (+) 597 WP_021034385.1 Fe-S biogenesis protein NfuA -

Sequence

Protein


Download         Length: 265 a.a.        Molecular weight: 31398.71 Da        Isoelectric Point: 5.9448

>NTDB_id=62148 HIFGL_RS00190 WP_021034378.1 41928..42725(+) (comA) [Haemophilus influenzae KR494]
MQFSLKNYLTLQIGIHRKQGYFDFVWFDDLEQPQSYQIFVNDRDFKNRFLQQLKTQYQGKTFPLQFVASIPAHLTWSKVL
MLPQVLNAQECHQQCKFVLEKELPISLDELWFDYRSTSLKQGFRLDVTAIRKSTAQTYLQDFQPFKINVLDVASNAILRA
FQYLLNAQVRSENTLFLFQEDDYCLAICERSQQSQILQSHENLTALYEQFTERFEGQLEQVFVYQIPSSHTPLPEHWQRV
ETELPFIALGNALWQKDLYQQKVGN

Nucleotide


Download         Length: 798 bp        

>NTDB_id=62148 HIFGL_RS00190 WP_021034378.1 41928..42725(+) (comA) [Haemophilus influenzae KR494]
ATGCAATTCTCCCTGAAAAATTACCTCACTTTACAAATCGGCATTCATCGTAAGCAGGGTTATTTTGATTTTGTGTGGTT
TGATGATCTTGAACAGCCACAAAGTTATCAAATTTTTGTTAATGATCGTGATTTTAAAAATCGTTTTTTACAACAGCTAA
AAACACAATATCAAGGGAAAACCTTTCCTTTACAGTTTGTGGCAAGCATTCCCGCTCACTTAACTTGGTCGAAAGTATTA
ATGTTGCCACAAGTGTTAAATGCGCAAGAATGTCATCAACAATGTAAATTTGTGCTTGAAAAAGAGCTGCCTATTTCTTT
AGATGAATTATGGTTTGATTATCGTTCTACCTCGTTAAAGCAAGGTTTTCGATTAGACGTTACTGCAATTCGTAAAAGTA
CTGCTCAAACTTATTTGCAAGATTTTCAGCCATTTAAAATTAATGTATTGGATGTTGCGTCAAATGCTATTTTGCGTGCA
TTTCAGTATTTGTTGAATGCACAAGTGCGGTCAGAAAATACCTTATTTTTATTTCAAGAAGATGACTATTGTTTGGCGAT
TTGTGAAAGATCGCAGCAATCGCAAATTTTACAATCTCACGAAAATTTGACCGCACTTTATGAACAATTTACCGAACGTT
TTGAAGGGCAACTTGAACAAGTTTTTGTTTATCAAATTCCCTCAAGTCATACGCCATTACCAGAACACTGGCAGCGAGTA
GAAACAGAACTCCCTTTTATTGCACTGGGCAACGCGCTATGGCAAAAAGATTTATATCAACAAAAAGTAGGTAACTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Haemophilus influenzae 86-028NP

97.358

100

0.974
  comA Haemophilus influenzae Rd KW20

93.962

100

0.94

Multiple sequence alignment