Detailed information NTG0621401

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: LK450_RS04600
• Genome accession: NZ_CP085939
• Coordinates: 945884..946474 (-)
• Length: 196 a.a.
• NCBI ID: WP_003025635.1
• Uniprot ID: A0A0P0N744
• Organism: Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569
• Function: degradation of ComX; require for competence development (at the early growth phase); repress competence development (at the mid-logarithmic growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 940884..951474

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LK450_RS04575 (LK450_04575)	-	941303..942067 (-)	765	WP_003032371.1	ABC transporter ATP-binding protein	-
LK450_RS04580 (LK450_04580)	-	942067..943017 (-)	951	WP_003032380.1	branched-chain amino acid ABC transporter permease	-
LK450_RS04585 (LK450_04585)	-	943021..943890 (-)	870	WP_018543650.1	branched-chain amino acid ABC transporter permease	-
LK450_RS04590 (LK450_04590)	-	944278..945441 (-)	1164	WP_003032423.1	ABC transporter substrate-binding protein	-
LK450_RS04595 (LK450_04595)	-	945524..945793 (-)	270	WP_003032401.1	YlbG family protein	-
LK450_RS04600 (LK450_04600)	clpP	945884..946474 (-)	591	WP_003025635.1	ATP-dependent Clp protease proteolytic subunit	Regulator
LK450_RS04605 (LK450_04605)	upp	946587..947216 (-)	630	WP_003025639.1	uracil phosphoribosyltransferase	-
LK450_RS04610 (LK450_04610)	mgtA	947314..949968 (-)	2655	WP_003032364.1	magnesium-translocating P-type ATPase	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21568.64 Da
• Isoelectric Point: 4.8097

>NTDB_id=621401 LK450_RS04600 WP_003025635.1 945884..946474(-) (clpP) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYINTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGAKGKRFMLPNAEYLIHQPMGGTGSGTQQTDMAIAAEHLLKTRNNLEKILADNSGK
TIKQVHKDAERDYWMSAQETLDYGFIDEIMANNNLN

Nucleotide

• Length: 591 bp

>NTDB_id=621401 LK450_RS04600 WP_003025635.1 945884..946474(-) (clpP) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCCTACGATATTTACTCACGCTTATTAAAAGATCGCAT
TATTATGCTGACGGGTCCTGTTGAGGACAATATGGCTAATTCCATTATTGCGCAATTACTTTTTCTTGATGCGCAGGATA
ATACCAAAGATATTTATCTTTACATCAATACGCCAGGCGGTTCCGTATCAGCTGGTCTAGCGATTGTTGATACCATGAAC
TTCATCAAATCAGATGTCCAAACAATTGTCATGGGGATGGCTGCTTCCATGGGAACCATTATTGCTTCAAGTGGTGCTAA
AGGCAAGCGCTTCATGTTGCCGAATGCAGAATACCTGATTCACCAACCAATGGGCGGAACTGGTAGCGGTACGCAACAAA
CCGATATGGCGATTGCGGCTGAGCATTTGCTGAAAACCCGGAATAACTTGGAGAAAATCCTTGCGGATAATTCAGGGAAA
ACCATTAAGCAAGTTCATAAAGATGCTGAACGTGACTACTGGATGAGTGCTCAAGAAACGCTAGATTATGGTTTCATTGA
TGAAATCATGGCAAATAACAACTTGAACTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A0P0N744

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus mutans UA159	92.821	99.49	0.923
clpP	Streptococcus thermophilus LMD-9	92.308	99.49	0.918
clpP	Streptococcus thermophilus LMG 18311	92.308	99.49	0.918
clpP	Streptococcus pyogenes JRS4	91.795	99.49	0.913
clpP	Streptococcus pyogenes MGAS315	91.795	99.49	0.913
clpP	Streptococcus pneumoniae D39	90.816	100	0.908
clpP	Streptococcus pneumoniae Rx1	90.816	100	0.908
clpP	Streptococcus pneumoniae R6	90.816	100	0.908
clpP	Streptococcus pneumoniae TIGR4	90.816	100	0.908
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	86.667	99.49	0.862
clpP	Lactococcus lactis subsp. cremoris KW2	86.154	99.49	0.857
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.995	98.469	0.561
clpP	Bacillus subtilis subsp. subtilis str. 168	56.25	97.959	0.551