Detailed information NTG0061924

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: SIR_RS19480
• Genome accession: NC_022246
• Coordinates: 1994201..1995391 (+)
• Length: 396 a.a.
• NCBI ID: WP_020999302.1
• Uniprot ID: -
• Organism: Streptococcus intermedius B196
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1989201..2000391

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SIR_RS19455 (SIR_1899)	comE	1991004..1991753 (-)	750	WP_003075488.1	competence system response regulator transcription factor ComE	Regulator
SIR_RS19460 (SIR_1900)	comD/comD1	1991753..1993078 (-)	1326	WP_003075490.1	GHKL domain-containing protein	Regulator
SIR_RS19790 (SIR_1901)	-	1993095..1993241 (-)	147	WP_003075491.1	bacteriocin	-
SIR_RS19475 (SIR_1903)	rlmH	1993518..1993997 (-)	480	WP_003075603.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
SIR_RS19480 (SIR_1904)	htrA	1994201..1995391 (+)	1191	WP_020999302.1	S1C family serine protease	Regulator
SIR_RS19485 (SIR_1905)	spo0J	1995446..1996213 (+)	768	WP_021003376.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 396 a.a.
• Molecular weight: 41833.94 Da
• Isoelectric Point: 10.1393

>NTDB_id=61924 SIR_RS19480 WP_020999302.1 1994201..1995391(+) (htrA) [Streptococcus intermedius B196]
MKNSSNFTKKFLWLFMVLAIGFIGGLLGNVTSSKLNKNNTTTTKVNHVTTSYKNTNSTTQAVNKVKDAVVSVITYANNKS
QNSIFGNDDFNSNNNNSQRVASEGSGVIYKKDSKYAYLVTNTHVINGASKVDIRLADGNKVPGEIVGSDTYSDISVVRIS
ASKVKSVAEFGDSSKLTVGETAIAIGSPLGSNYANTVTQGIISSLNRNVSLKSEDGQTISTQAIQTDTAINPGNSGGPLV
NIQGQVIGITSSKIASNRGTSVEGLGFAIPSNDVTNIISQLESNGAVTRPALGIQMIDISNLSSSDLSRLKLPAKVTAGV
VVRSAQSGMPAAGKLQKYDVITKIDGKDISSANDLQSALYKHSIGDDIKITFYRNGKETTTTIKLTKSTKDLNSNN

Nucleotide

• Length: 1191 bp

>NTDB_id=61924 SIR_RS19480 WP_020999302.1 1994201..1995391(+) (htrA) [Streptococcus intermedius B196]
ATGAAAAACTCTTCAAATTTCACAAAAAAATTCTTATGGCTTTTCATGGTCTTAGCTATAGGTTTTATTGGTGGTTTATT
AGGAAATGTAACTTCTTCAAAATTAAATAAAAACAACACAACTACCACTAAGGTTAACCATGTTACTACATCTTATAAAA
ATACCAATTCTACAACACAGGCGGTCAATAAAGTAAAGGATGCTGTTGTTTCTGTTATTACCTATGCTAATAATAAATCT
CAAAATAGCATTTTTGGAAATGATGACTTTAATAGTAACAATAATAACTCACAAAGAGTAGCAAGCGAAGGTTCAGGGGT
TATTTATAAAAAAGACAGTAAGTATGCCTATCTTGTAACTAATACTCATGTTATTAATGGTGCTAGTAAAGTGGATATTC
GTTTAGCGGATGGTAACAAAGTTCCAGGAGAAATCGTAGGCTCAGATACTTACTCAGATATTTCTGTCGTCCGTATTAGT
GCAAGCAAAGTCAAGTCAGTTGCTGAATTTGGTGATTCTAGTAAATTAACTGTTGGAGAAACTGCTATTGCTATTGGTAG
CCCACTTGGATCAAATTATGCAAATACTGTTACTCAAGGAATTATTTCTAGCTTAAATCGTAATGTGTCTTTAAAATCTG
AAGATGGTCAAACTATCTCTACTCAGGCTATTCAAACAGATACAGCGATTAATCCTGGGAATTCTGGTGGTCCACTTGTA
AATATCCAAGGGCAAGTTATTGGTATTACTTCAAGTAAAATTGCTAGTAATCGTGGAACATCTGTAGAGGGATTAGGTTT
TGCTATTCCATCTAATGATGTCACCAACATCATCAGCCAATTGGAATCAAATGGAGCAGTTACGCGACCAGCTTTAGGAA
TTCAAATGATTGATATTAGTAATCTATCTAGTTCTGATTTATCACGTTTGAAACTTCCAGCAAAAGTGACTGCAGGAGTT
GTTGTTCGTTCAGCTCAGTCTGGAATGCCTGCAGCAGGAAAACTTCAAAAATATGATGTTATTACAAAGATAGATGGAAA
AGACATTTCCTCAGCAAATGATTTACAATCTGCTTTATACAAACATTCAATTGGTGATGATATAAAAATTACATTTTATC
GTAATGGAAAAGAAACAACCACCACCATTAAACTTACAAAATCTACAAAAGATTTAAATTCAAATAATTGA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (290-385)

• Trypsin-like peptidase domain (Trypsin_2) (104-249)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	74.442	100	0.758
htrA	Streptococcus mitis NCTC 12261	71.537	100	0.717
htrA	Streptococcus pneumoniae D39	71.285	100	0.715
htrA	Streptococcus pneumoniae TIGR4	71.285	100	0.715
htrA	Streptococcus pneumoniae R6	71.285	100	0.715
htrA	Streptococcus pneumoniae Rx1	71.285	100	0.715
htrA	Streptococcus mutans UA159	57.033	98.737	0.563