Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   LIS81_RS13520 Genome accession   NZ_CP085399
Coordinates   2628508..2629089 (-) Length   193 a.a.
NCBI ID   WP_000991609.1    Uniprot ID   A0A853X8N5
Organism   Bacillus tropicus strain CK18     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2626227..2649909 2628508..2629089 within 0


Gene organization within MGE regions


Location: 2626227..2649909
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LIS81_RS13510 (LIS81_13515) - 2626227..2627432 (-) 1206 WP_000370618.1 glycine betaine/L-proline ABC transporter ATP-binding protein -
  LIS81_RS13515 (LIS81_13520) - 2627604..2628461 (+) 858 WP_042515006.1 glycine betaine ABC transporter substrate-binding protein -
  LIS81_RS13520 (LIS81_13525) clpP 2628508..2629089 (-) 582 WP_000991609.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  LIS81_RS13525 (LIS81_13530) - 2629111..2629797 (-) 687 WP_226639382.1 RNA polymerase subunit sigma-70 -
  LIS81_RS13530 (LIS81_13535) - 2629941..2630261 (+) 321 WP_001125388.1 2Fe-2S iron-sulfur cluster-binding protein -
  LIS81_RS13535 (LIS81_13540) rpiA 2630266..2630928 (+) 663 WP_226639383.1 ribose 5-phosphate isomerase A -
  LIS81_RS13540 (LIS81_13545) - 2631035..2631469 (+) 435 WP_226639384.1 GNAT family N-acetyltransferase -
  LIS81_RS13545 (LIS81_13550) - 2631600..2632967 (-) 1368 WP_252210448.1 lytic polysaccharide monooxygenase -
  LIS81_RS13550 (LIS81_13555) - 2633325..2634518 (-) 1194 WP_226639387.1 macrolide family glycosyltransferase -
  LIS81_RS13555 (LIS81_13560) - 2634604..2635284 (-) 681 WP_226639389.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -
  LIS81_RS13560 (LIS81_13565) - 2635431..2635934 (-) 504 WP_074562440.1 DNA topology modulation protein -
  LIS81_RS13565 (LIS81_13570) - 2635956..2636342 (-) 387 WP_061658704.1 DUF2809 domain-containing protein -
  LIS81_RS13570 (LIS81_13575) - 2636408..2637115 (-) 708 WP_226639391.1 class I SAM-dependent methyltransferase -
  LIS81_RS13575 (LIS81_13580) - 2637137..2637490 (-) 354 WP_000648514.1 MmcQ/YjbR family DNA-binding protein -
  LIS81_RS13580 (LIS81_13585) - 2637504..2637911 (-) 408 WP_226639393.1 GNAT family N-acetyltransferase -
  LIS81_RS13585 (LIS81_13590) - 2638342..2639715 (+) 1374 Protein_2613 S-layer homology domain-containing protein -
  LIS81_RS13590 (LIS81_13595) - 2639718..2639981 (+) 264 WP_226639395.1 DUF3006 domain-containing protein -
  LIS81_RS13595 (LIS81_13600) - 2639992..2640798 (-) 807 WP_226639397.1 GH25 family lysozyme -
  LIS81_RS13600 (LIS81_13605) - 2641075..2641491 (-) 417 WP_000809322.1 GNAT family N-acetyltransferase -
  LIS81_RS13605 (LIS81_13610) - 2641524..2641895 (-) 372 WP_061402936.1 hypothetical protein -
  LIS81_RS13610 (LIS81_13615) - 2641892..2642668 (-) 777 WP_226639399.1 serine hydrolase -
  LIS81_RS13615 (LIS81_13620) - 2642813..2643325 (-) 513 WP_226639401.1 GNAT family N-acetyltransferase -
  LIS81_RS13620 (LIS81_13625) - 2643360..2644370 (-) 1011 WP_226639403.1 hypothetical protein -
  LIS81_RS13625 (LIS81_13630) - 2644357..2644704 (-) 348 WP_000339349.1 PadR family transcriptional regulator -
  LIS81_RS13630 (LIS81_13635) - 2644886..2645206 (-) 321 WP_226639405.1 DUF952 domain-containing protein -
  LIS81_RS13635 (LIS81_13640) - 2645278..2647347 (-) 2070 WP_226639408.1 3'-5' exonuclease -
  LIS81_RS13640 (LIS81_13645) - 2647718..2648584 (+) 867 WP_226639410.1 CPBP family glutamic-type intramembrane protease -
  LIS81_RS13645 (LIS81_13650) - 2648605..2649348 (-) 744 WP_226639412.1 class I SAM-dependent methyltransferase -
  LIS81_RS13650 (LIS81_13655) - 2649526..2649909 (-) 384 WP_226639415.1 gamma-glutamylcyclotransferase -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21192.49 Da        Isoelectric Point: 5.3394

>NTDB_id=617725 LIS81_RS13520 WP_000991609.1 2628508..2629089(-) (clpP) [Bacillus tropicus strain CK18]
MNAIPYVVEQTKLGERSYDIYSRLLKDRIIIIGSEINDQVASSVVAQLLFLEAEDAEKDIFLYINSPGGSTTAGFAILDT
MNLIKPDVQTLCMGFAASFGALLLLSGAKGKRFALPNSEIMIHQPLGGAKGQATEIEITAKRILKLKHDINKMIAEKTGQ
PIERVAHDTERDYFMTAEEAKAYGIVDDVVTKK

Nucleotide


Download         Length: 582 bp        

>NTDB_id=617725 LIS81_RS13520 WP_000991609.1 2628508..2629089(-) (clpP) [Bacillus tropicus strain CK18]
ATGAATGCAATTCCATATGTAGTGGAACAAACGAAATTAGGAGAACGTTCCTATGATATATATTCAAGGTTATTAAAAGA
TCGTATTATTATTATCGGTTCAGAAATAAATGATCAAGTAGCGAGTAGTGTCGTAGCTCAATTATTATTTTTAGAAGCAG
AAGATGCAGAGAAAGATATATTTTTATACATTAATAGCCCCGGCGGATCAACGACAGCGGGATTTGCTATATTAGATACA
ATGAATTTAATTAAACCTGATGTGCAAACGCTATGCATGGGCTTTGCAGCATCATTTGGTGCATTGTTATTATTATCAGG
TGCAAAAGGAAAACGATTTGCACTCCCAAATAGTGAAATTATGATTCATCAGCCGCTTGGTGGTGCAAAAGGGCAGGCAA
CAGAAATTGAAATAACAGCAAAAAGGATATTGAAGTTAAAGCATGATATTAATAAAATGATTGCAGAAAAAACGGGGCAA
CCGATTGAAAGAGTAGCACATGATACAGAAAGAGATTATTTTATGACTGCAGAAGAAGCAAAGGCATATGGGATTGTAGA
TGATGTTGTTACGAAAAAATAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(14-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A853X8N5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

68.063

98.964

0.674
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

67.196

97.927

0.658
  clpP Streptococcus pyogenes JRS4

56.085

97.927

0.549
  clpP Streptococcus pyogenes MGAS315

56.085

97.927

0.549
  clpP Streptococcus pneumoniae R6

55.208

99.482

0.549
  clpP Streptococcus pneumoniae TIGR4

55.208

99.482

0.549
  clpP Streptococcus pneumoniae Rx1

55.208

99.482

0.549
  clpP Streptococcus thermophilus LMG 18311

55.208

99.482

0.549
  clpP Streptococcus thermophilus LMD-9

55.208

99.482

0.549
  clpP Streptococcus pneumoniae D39

55.208

99.482

0.549
  clpP Streptococcus mutans UA159

53.968

97.927

0.528
  clpP Lactococcus lactis subsp. cremoris KW2

51.852

97.927

0.508
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

50.265

97.927

0.492